(Sr.) Manager In Vivo Pharmacology (Suzhou, JS, CN, 215123)

苏州，中国   |   全职   |   Job ID: 11912

About the role:

As Manager or Senior Manager, In Vivo Pharmacology, you will lead oncology studies that help BioNTech assess treatment approaches and make informed decisions about candidate development. Your expertise in complex tumor models will help connect study findings to our work developing new approaches to address cancer.Reporting to the Head of In Vivo Pharmacology, you will guide a research team and partner with colleagues across Drug Discovery. You'll shape study plans, interpret results and support rigorous, timely research, with a strong focus on animal welfare and data quality.

Your contribution:

Lead and develop the in vivo pharmacology team, setting priorities and allocating resources to deliver study milestones

Establish, characterize and qualify complex tumor models, selecting models that fit each research question

Design and oversee oncology efficacy and combination studies with clear hypotheses, controls, endpoints and robust study methods

Coordinate pharmacodynamic and mechanism-of-action studies, integrating tumor response, biomarkers and pharmacokinetic and pharmacodynamic dataInterpret findings, communicate model limitations and recommend next steps to support candidate selection and project decisions

Ensure high standards for animal welfare, study records and data quality; oversee external research partners and study delivery

A good match:

Bachelor's degree or higher in pharmacology, oncology, veterinary medicine, immunology, biology or a related discipline; an advanced degree is preferred

Hands-on experience developing, characterizing and applying complex tumor models, such as orthotopic, metastatic, patient-derived xenograft, syngeneic or humanized mouse models

Experience independently designing, executing, troubleshooting and interpreting oncology efficacy studies, including statistical planning and pharmacodynamic endpoints

People-management experience leading in vivo pharmacology or related research teams, including staff development, resource planning and oversight of concurrent studies or external research organizations

Strong understanding of tumor biology and the tumor microenvironment, with experience integrating efficacy, tolerability, biomarker and pharmacokinetic and pharmacodynamic data

Knowledge of animal welfare, ethics review, humane endpoints and the 3Rs, plus strong planning and communication skills and the ability to discuss scientific work in EnglishAt Senior Manager level, broader leadership across multiple projects and experience developing team capabilities are expected.

BioNTech 重视每一位团队成员的福祉，为多元化的员工提供全面的福利保障。我们提供具有市场竞争力的薪酬方案，具体将根据职位、工作地点及候选人资历与经验综合确定。注：各项福利的实际适用范围、享有条件及具体内容可能因所在地而异，最终以公司内部政策及当地法律法规为准。

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重要提示：

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提交申请即视为您知悉，招聘流程中将依相关法律法规进行背景调查。如您进入候选名单，BioNTech 将通过合作服务机构“HireRight”开展背景调查工作，招聘专员将及时与您沟通具体安排。

我们诚挚期待您的加入。