Vertex Pharmaceuticals Inc (US) Posted September 10, 2026

Comparative Medicine Manager

5005, United States Full time
Notify me about similar jobs

Vertex Pharmaceuticals Inc (US) is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Job Description

General Summary:

The Comparative Medicine Manager, Vivarium Operations is responsible for leading, supporting, and coordinating key aspects of the San Diego Research Site Vivarium and IACUC operations/management, with a primary focus on maintaining the day-to-day operations of the San Diego vivarium.  This role serves as a critical partner to research teams by overseeing animal procurement, supporting IACUC-related processes, providing technical expertise for animal studies, and ensuring in vivo users are appropriately trained and onboarded. This person would serve as the Global Comparative Medicine liaison for San Diego.

The position also plays a central role in the development, implementation, and continuous improvement of IACUC policies, guidelines, SOPs, and training materials to promote compliance, operational excellence, and high standards of animal welfare.

Key Responsibilities:

Vivarium Operations

Support and help maintain the day-to-day operations of the San Diego vivarium to ensure efficient, compliant, and uninterrupted research support.

Management of contract personnel for San Diego vivarium.

Management of Vertex activities at contracted site for Seattle.

Work across sites for harmonization of processes as applicable.

Partner with internal stakeholders and vivarium staff to identify operational needs and implement process improvements.

Monitor operational workflows to ensure alignment with institutional, regulatory, and animal welfare standards in accordance with local guidelines.

Provide weekend support as needed.

Global Animal Procurement

Coordinate global animal procurement activities to ensure timely and reliable sourcing of animals for research programs.

Collaborate with internal research teams, vendors, and external partners to support study timelines and business needs.

Track procurement logistics and resolve issues related to supply, scheduling, or study support.

IACUC Support and Compliance

Assist with IACUC management activities, including protocol-related support, documentation, and coordination with internal stakeholders.

Contribute to the development, revision, and implementation of IACUC policies, guidelines, and SOPs.

Help ensure vivarium and in vivo activities are conducted in compliance with institutional policies and applicable regulations.

Support inspection readiness and corrective actions as needed.

Technical Support for Animal Studies

Oversee technical support for animal studies and serve as a resource to in vivo users and project teams.

Assist with study planning and execution by offering operational/technical support.

Troubleshoot technical or operational issues that may impact in vivo research activities.

Training and Onboarding

Work with Global Trainer on providing technical training to in vivo users to ensure safe, effective, and compliant conduct of animal studies.

Assist in the onboarding of new in vivo users, including orientation to vivarium procedures, expectations, and required training.

Work with Global Trainer to develop and maintain training content related to vivarium operations, animal procedures, and compliance requirements.

Promote best practices in animal care, handling, documentation, and study conduct.

Documentation and Continuous Improvement

Develop, update, and maintain training documentation, SOPs, guidance documents, and other controlled content.

Identify opportunities to improve operational efficiency, user experience, and compliance processes across vivarium activities.

Support standardization of practices across local and global vivarium-related functions where applicable.

Education and Experience

Bachelor’s degree in animal science, biology, veterinary technology, life sciences, or related field required.

A master’s degree in a relevant scientific or operational discipline is preferred.

Experience supporting vivarium operations, laboratory animal research, or in vivo study execution.

Experience with IACUC processes, animal welfare regulations, and related compliance requirements.

Experience developing SOPs, policies, training materials, and procedural documentation.

Experience training technical users and supporting onboarding in a research environment preferred.

Experience coordinating cross-functional projects and working with global stakeholders is preferred.

AALAS certification ( LATg), ILAM and/or CPIA preferred.

Preferred Attributes, Skills, and Abilities

Ability to provide hands-on and technical support for in vivo studies.

Strong organizational and project management skills with the ability to manage multiple priorities.

Excellent written and verbal communication skills.

Ability to develop clear, effective, and compliant policies, SOPs, guidelines, and training content.

Strong collaboration skills with the ability to work effectively across scientific, operational, and compliance teams.

Detail-oriented with a commitment to quality, animal welfare, and operational excellence.

Demonstrated ability to work in a fast-paced, matrixed, and collaborative research environment.

Strong problem-solving skills and a proactive approach to operational challenges.

Ability to influence and support adoption of best practices across in vivo users and stakeholders.

Global mindset with the ability to coordinate across sites, functions, and external partners.

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

$113,400 - $170,000

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:

1.    Hybrid: work remotely up to two days per week; or select

2.    On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Job details

Seniority
Manager
Function
Drug Discovery & Preclinical Research
Therapeutic area
Not listed
Location
5005, United States
Employment type
Full time

How this role compares

Computed from every other active Drug Discovery & Preclinical Research role in our database, not just this employer's listings.

We currently track 53 comparable Manager Drug Discovery & Preclinical Research roles across 27 biopharma companies.

53Comparable roles tracked
47Currently active
27Companies hiring similar roles
7Countries represented

Salary context

15 of 53 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $113,400/yr – $170,000/yr
Lowest disclosed · Associate Scientist, Pharmacology (Boston, US, 02210) · Servier $106,000/yr – $120,000/yr
Peer group range $113,000 – $231,700 (median $196,900)

Where these roles are based

Top locations among the 53 comparable roles

United States46
Canada2
Switzerland1
Spain1
Germany1
China1

+ 1 more countries

Seniority mix

53 of 53 peers have a known seniority level

Associate24
Associate Director21
Manager8

Therapeutic area mix

11 of 53 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology5
Cardiovascular / CVRM4
Neuroscience1
Immunology1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
Pfizer Cambridge, United States Manager
Same function Same seniority Same country
60%similar
Amgen Inc. Thousand Oaks, United States Manager
Same function Same seniority Same country
60%similar
Vertex Pharmaceuticals Inc (US) Boston, United States Manager
Same function Same seniority Same country
60%similar
Neurocrine Biosciences Inc. US CA San Diego, United States Manager
Same function Same seniority Same country
60%similar
AstraZeneca Cambridge, Massachusetts, United States of America Manager
Same function Same seniority Same country
50%similar
Pfizer Cambridge, United States Associate
Same function Adjacent seniority Same country

Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Comparative Medicine Operation Manager
Pfizer · Cambridge, United States · Manager
Function Therapeutic area Seniority Country
60%
Program Manager, Preclinical Programs
Neurocrine Biosciences Inc. · US CA San Diego, United States · Manager
Function Therapeutic area Seniority Country
50%
Associate Director, ADC platform in Oncology Drug Discovery
Novartis · Cambridge (USA), United States · Associate Director
Function Therapeutic area Adjacent seniority Country
50%
Scientific Associate Director
Signal Pharmaceuticals, L · San Diego, United States · Associate Director
Function Therapeutic area Adjacent seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.