BioNTech Posted October 1, 2026

(Senior) System Engineer Digital Solutions R&D (Mainz, RP, DE, 55116)

Mainz, Germany Type not listed
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About this opportunity

Mainz, Germany   |   full time   |   Job ID: 11788

About the Role:

BioNTech currently runs a variety of digitalization projects including SAP ERP, MES and LIMS systems. As part of our growth activities our digital solutions will continuously be extended by the implementation and connection of systems for the scientific research and development at BioNTech and we want to increase our efforts to bring more digital solutions in to support our R&D processes. Thus, a global R&D digital ecosystem including various capabilities is currently rolled out to our labs.

As a (Senior) System Engineer, you will drive the development, deployment, and maintenance of software solutions supporting R&D lab digitalization, taking technical ownership throughout the system lifecycle. You will lead solution design, implementation, and operational setup, ensuring alignment with business needs and governance standards. Integrating these systems will be a primary focus of the role, alongside other responsibilities. With deep expertise in R&D lab systems, you will collaborate with cross-functional teams and stakeholders to deliver efficient, standardized processes and maintain system functionality.

Your Contribution:

Utilize your market expertise in commonly used lab software applications, such as LIMS, ELN, automation & device software, data evaluation software

Develop technical solutions tailored to the respective business needs while ensuring alignment with the respective governance

Take ownership of technical aspects during solution implementation and actively contribute to project execution

Drive the successful delivery of assigned projects with a focus on quality and efficiency

Drive the integration strategy of BioNTech and the R&D digital ecosystem by acting as Single point of contact for integration-related questions, from ideation over implementation to operation

Manage the operation and lifecycle management of the assigned complex applications

Establish and oversee technical change management processes for applications within scope

Configure software solutions to meet user requirements and enhance functionality

Maintain stakeholder satisfaction by ensuring the software landscape meets expectations throughout all lifecycle phases

A Good Match:

Degree in Biology, Computer Science, Engineering, Pharmacy, or a related field, combined with several years of relevant professional experience in a similar role.

Strong technical aptitude with the ability to identify and implement optimal solutions for complex challenges

First-hand technical hands-on experience with System integration and related technologies (such as REST, SOAP, GraphQL), ideally using an Integration Layer such as Mulesoft is required

Proven expertise in integrating systems within laboratory environments is a plus

Proficiency in scripting languages such as Python, JavaScript, or PowerShell is required; basic knowledge of modern programming languages such as Java or C# is considered a plus.

Excellent communication skills, with the ability to collaborate effectively across diverse teams; fluency in English is required, German language skills are an advantage

Hands-on experience working in agile environments and methodologies

Your Benefits:

It's our priority to support you:

Your flexibility: flexible hours | vacation account

Your growth: Digital Learning | Performance & talent development | leadership development | Apprenticeships | LinkedIn Learning

Your value: Your voice at the table | Culture on an equal footing | Opportunities to shape & impact | Support for your full potential

Your health and lifestyle: Company bike

Your mobility: Job ticket | Deutschlandticket

Your life phases: Employer-funded pension | Childcare

Apply now - We look forward to your application!

Apply to our Mainz, Germany   location by sending us your documents via our online form. For any questions, contact our talent acquisition team on: + 49 (0) 6131-9084-1291 (Monday-Friday from 1 PM to 3 PM CET).

Job ID 11788 (please always specify if you have any questions)

By submitting your application, you acknowledge that a background check will be conducted as part of the recruitment process in accordance with applicable laws and regulations. If you are considered for the position, BioNTech will conduct the background check through our service provider ‘HireRight’. You will be informed accordingly by your BioNTech-Recruiter.

Note for applications within Europe: Please note that if you wish to claim travel expenses incurred in connection with an in-person interview, we are obliged to carry out a sanctions list check*. This is carried out by our partner, HireRight. Travel expenses will only be reimbursed if this sanctions list check does not yield any matches. Reimbursement can be made provided that the check is successfully completed.

* Your first name, surname and date of birth will be processed for the sanctions list check. The legal basis for carrying out the sanctions list check for positions at BioNTech in Europe is BioNTech’s legitimate interest. Please note that BioNTech will not carry out the sanctions list check if no travel expenses are to be reimbursed. If you do not give BioNTech your consent to the sanctions list check, your travel expenses cannot be reimbursed. This will not affect your application.

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Job details

Seniority
Senior
Function
Information Technology
Therapeutic area
Not listed
Location
Mainz, Germany
Employment type
Not listed

How this role compares

Computed from every other active Information Technology role in our database, not just this employer's listings.

We currently track 608 comparable Senior Information Technology roles across 60 biopharma companies.

608Comparable roles tracked
567Currently active
60Companies hiring similar roles
33Countries represented

Salary context

101 of 608 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Highest disclosed · Senior Staff Engineer - DevSecOps · Exelixis Inc $219,000/yr – $311,000/yr
Peer group range $98,050 – $265,000 (median $183,250)

Where these roles are based

Top locations among the 608 comparable roles

India239
United States216
Spain31
Poland21
United Kingdom12
Philippines11

+ 27 more countries

Seniority mix

608 of 608 peers have a known seniority level

Senior407
Principal106
Associate Director95

Therapeutic area mix

4 of 608 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology3
Vaccines & Infectious Disease1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
BioNTech Mainz, Germany Senior
Same function Same seniority Same country
60%similar
BioNTech Mainz, Germany Senior
Same function Same seniority Same country
60%similar
BioNTech Mainz, Germany Senior
Same function Same seniority Same country
60%similar
Merck KGaA Weiterstadt, Hessen, Germany Senior
Same function Same seniority Same country
50%similar
BioNTech Mainz, Germany Associate Director
Same function Adjacent seniority Same country
50%similar
Roche Penzberg, Bavaria, Germany Principal
Same function Adjacent seniority Same country

Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

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How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
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BioNTech · Mainz, Germany · Senior
Function Therapeutic area Seniority Country
60%
(Senior) Software Engineer (all genders, full-/part-time)
Merck KGaA · Weiterstadt, Hessen, Germany · Senior
Function Therapeutic area Seniority Country
45%
Senior Software Developer/Scrum Master C#
Roche · Sant Cugat del Vallès, Barcelona, Spain · Senior
Function Therapeutic area Seniority Country
45%
Senior IT Technology Specialist
Regeneron Pharmaceuticals, Inc (USA) · Renss, United States · Senior
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.