Amgen Inc. Posted September 1, 2026

Sr Manager Business Performance & Digital Enablement - Remote

Remote, United States Full time
Medical Affairs Manager
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About this opportunity

Career Category

Medical Affairs

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission, to serve patients living with serious illnesses, drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Sr Manager Business Performance & Digital Enablement

Live

What you will do

Let’s do this. Let’s change the world. The AUEG (Access & Use Evidence Generation) Business Performance Sr. Mgr. is responsible for translating Global AUEG Portfolio Strategy, Governance, and Process framework into execution ready and scalable digital operating models with advancements in technology including AI. This role serves as the integrator and liaison between AUEG Capability and internal Digital Technology & Innovation (DTI), Artificial Intelligence & Data (AI& D) teams and external partners. The Sr. Manager leads the build and delivery of the cross functional, matrixed AUEG technology platform (AUGment) aimed at enabling disciplined prioritization, governance, execution, and management of global, regional and local AUEG activities in collaboration with DTI, AI&D and functional partners in Medical, R&D, and Global Markets & Policy.

This role leads delivery of the enhancement road map of the evolution of AUEG capability that will enable timely prioritization and execution of AUEG activities and demonstrates the realized AUEG impact. As the business owner for the AUGment platform and a strategic business partner to DTI, Medical Data & Analytics (MD&A), and AI& D, the Senior Manager translates business priorities into scalable capabilities enabled through business processes and technology to impact realization.

Working across a highly matrixed environment, this role partners cross-functionally to strengthen organizational performance to accelerate adoption of technology-enabled capabilities and deliver measurable business outcomes. Success in this role requires strong business acumen, information technology understanding and ability to influence across organizational boundaries to deliver meaningful results.

Key Responsibilities

Business Strategy & Capability Development

Translate AUEG Capability strategy and long-term roadmap into scalable, operating models, business processes for enterprise execution, with clean CORE and FAIR data technology-enabled solutions.

Manage and execute on governance, performance measures, and operating standards that support consistent execution and informed decision-making via technology solutions.

Partner with AUEG leadership to continuously evolve AUEG capabilities and improve performance.

Drive continuous improvement through people, processes, technology, and data.

AUGment Business Ownership & Digital Enablement

Partner with DTI, AI&D Product Managers and Solution Architects to translate strategic priorities into technology-enabled business capabilities.

Serve as the business owner for AUGment and other integrated business enablement technologies.

Oversee delivery of the AUGment enhancement roadmap aligned with AUEG priorities.

Lead business requirements, process design, user acceptance testing, deployment, and organizational adoption.

Identify and lead opportunities to leverage AI, automation, and emerging technologies to continuously evolve business capabilities and improve business performance.

Oversee business-owned collaboration and knowledge management solutions that support the AUEG capability.

Data Strategy & Business Insights

Define the AUEG data strategy, roadmap and business reporting framework.

Strengthen data quality, governance, and stewardship of business information.

Establish and continuously evolve meaningful business impact metrics, KPIs, and executive dashboards.

Deliver actionable portfolio insights that support strategic and operational decisions.

Advance AI-ready data foundations and analytical capabilities that enable evolving capabilities.

Strategic Partnerships, Adoption & People Leadership

Serve as the primary business partner to DTI and MD&A.

Build trusted partnerships across Medical, Technology, Data & Analytics, R&D, Global Markets & Policy, Commercialization, Finance, Procurement, and external vendor partners.

Translate evolving needs into prioritized capabilities, roadmap enhancements, and technology investments.

Lead stakeholder engagement, communication, training, and adoption of technology-enabled business capabilities.

Identify business risks, develop & implement mitigation strategies.

Lead a high-performing matrixed team responsible for operational support, reporting, platform administration, and business services for the AUEG organization.

Coach and develop team members while establishing scalable operating practices, performance expectations, and continuous improvement initiatives that enable reliable, high-quality business services.

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The strategic professional we seek is a motivated professional with these qualifications.

Basic Qualifications:

Doctorate degree and 2 years of business performance and digital enablement experience OR

Master’s degree and 6 years of business performance and digital enablement experience OR

Bachelor’s degree and 8 years of business performance and digital enablement experience OR

Associate’s degree and 10 years of business performance and digital enablement experience OR

High school diploma / GED and 12 years of business performance and digital enablement experience

In addition to meeting at least one of the above requirements, you must have a minimum of 2 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources.  Your managerial experience may run concurrently with the required technical experience referenced above

Preferred Qualifications

Advanced degree in Business, Life Sciences, Computer Science, Engineering, or a related discipline.

8+ years of experience leading business operations, business capability enablement, digital enablement, business performance, technology implementation, or business transformation within the pharmaceutical, biotechnology, or healthcare industry.

Experience serving as a business owner or platform owner for enterprise technology platforms that enable scalable business capabilities.

Demonstrated success evolving technology-enabled capabilities through process optimization, technology enablement, and operational excellence.

Experience integrating business, technology, data, and AI capabilities to deliver measurable business outcomes.

Strong understanding of Medical Affairs, Evidence Generation, drug development, commercialization, and the healthcare ecosystem.

Experience leading cross-functional initiatives in highly matrixed organizations.

Experience managing business operations, budgets, vendors, or external partners.

Knowledge of GxP, SOPs, regulatory requirements, and validated business processes.

Experience driving organizational adoption and continuous improvement of technology-enabled business capabilities.

Thrive

What you can expect from us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

Stock-based long-term incentives

Award-winning time-off plans and bi-annual company-wide shutdowns

Flexible work models, including remote and hybrid work arrangements, where possible

Apply now for a career that defies imagination

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

. Salary Range

158,255.55USD -214,110.45 USD

Job details

Seniority
Manager
Function
Medical Affairs
Therapeutic area
Not listed
Location
Remote, United States
Employment type
Full time

How this role compares

Computed from every other active Medical Affairs role in our database, not just this employer's listings.

We currently track 282 comparable Manager Medical Affairs roles across 82 biopharma companies.

282Comparable roles tracked
254Currently active
82Companies hiring similar roles
38Countries represented

Salary context

63 of 282 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Lowest disclosed · Clinical Research Associate · Pfizer $68,600/yr – $114,300/yr
Peer group range $91,450 – $231,700 (median $198,000)

Where these roles are based

Top locations among the 282 comparable roles

United States85
Japan29
China23
China's Mainland22
Germany16
India16

+ 32 more countries

Seniority mix

282 of 282 peers have a known seniority level

Manager148
Associate Director71
Associate63

Therapeutic area mix

86 of 282 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology37
Respiratory8
Neuroscience8
Immunology8
Dermatology & Aesthetics7
Cardiovascular / CVRM6
Gastroenterology5
Vaccines & Infectious Disease4
Rare Disease2
Ophthalmology1

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How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

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Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.