Genzyme Corporation Posted September 3, 2026

Senior Program Manager (SPM) - Mastocytosis

Cambridge, United States Full time
Medical Affairs Manager
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About this opportunity

Job title: Senior Program Manager - Mastocytosis

Location: Cambridge, MA

About the Job

The Senior Program Manager (SPM) will drive business-related initiatives within the Mastocytosis Therapeutic Area (TA), serving as a key operational partner to the Medical Program Lead (MPL) and the Mastocytosis Global Medical Team (GMT).

Working collaboratively with internal stakeholders and external Alliance partners (where applicable), the SPM will ensure seamless execution of lifecycle management (LCM) initiatives, launch deliverables, and strategic programs aligned with product development stages.

Operating within a dynamic matrix environment, the SPM will coordinate cross-functional resources and activities to deliver on priorities outlined in the Global Medical Plans, ensuring strategic alignment and operational excellence across all TA-specific initiatives.

Join the engine of Sanofi's mission, where deep immuno-science meets bold, AI-powered research. In R&D, you'll drive breakthroughs that could turn the impossible into possible for millions.

About Sanofi:

We're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that   treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives.

Main Responsibilities:

 

Strategic Partnership & Leadership • Lead program management initiatives for Mastocytosis in strategic partnership with the Medical Program Lead (MPL) • Collaborate with Global Medical Director to operationalize Global Medical Team strategies and deliverables • Drive integrated evidence generation planning through cross-functional partnerships with Global Medical Directors, Brand teams, and functional leads

Study Lifecycle & Portfolio Management • Oversee comprehensive study lifecycle management, including process optimization, timeline coordination, and budget oversight for:

Company-Sponsored Studies (CSS): Manage approval process and serve as central Medical liaison for Clinical Sciences and Operations (CSO) communications and partnerships

Investigator-Sponsored Studies (ISS) & Real-World Evidence (RWE): Partner with key stakeholders to capture operational details, study milestones, and budget requirements aligned with Medical plans

Compliance & Reporting: Ensure adherence to study compliance requirements

Operational Excellence & Process Management • Optimize cross-functional communication and decision-making through meeting facilitation and stakeholder engagement • Streamline operational workflows to ensure compliance with internal SOPs and external regulatory guidelines • Utilize harmonized Program Management Tools to manage portfolio-level activities across the Program Management organization

Stakeholder & Alliance Partner Engagement • Build and maintain strategic partnerships with internal teams and external collaborators • Serve as primary advocate for alliance partner relationships (where applicable), ensuring alignment with collaboration objectives and deliverables • Provide specialized program management support for Therapeutic Area-specific initiatives and strategic priorities

About You

Basic Qualifications:

The ideal candidate brings a strong foundation in the biotech/pharmaceutical industry, combined with proven expertise in Project/Program Management. A scientific background and Medical Affairs experience are highly preferred.

Education

Bachelor of Science (BS) required

Advanced degree in a scientific discipline strongly preferred

Experience

Minimum 5 years of project/program management experience within biotech/pharma, clinical, or scientific environments

Demonstrated ability to translate strategic objectives into actionable tactical plans

Proven track record of managing complex, cross-functional programs from initiation through completion with minimal supervision

Medical Affairs experience preferred

 

Core Competencies

🔹 Program Management Excellence

Deep understanding of project/program management methodologies, frameworks, and best practices

Skilled in end-to-end project ownership, including scope, timelines, risk management, and budget oversight

Proficient in developing and maintaining reporting dashboards with key performance metrics using harmonized organizational tools

🔹 Leadership & Collaboration

Demonstrated ability to lead and influence cross-functional teams within a matrix environment

Strong management skills with the ability to engage effectively at all organizational levels

Proven ability to foster a culture of teamwork, accountability, and collaboration

🔹 Communication & Organization

Exceptional interpersonal and communication skills, both written and verbal

Highly organized with the ability to manage competing priorities and tight deadlines with professionalism and composure

Comfortable operating in a fast-paced, dynamic environment with shifting priorities

Technical Skills

Advanced proficiency in Microsoft Office Suite (Word, Excel, PowerPoint, Outlook)

Working knowledge of project/program management software (e.g., SharePoint Apps, MS Project, or equivalent tools)

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.

• Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.

• Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.

• Help improve the lives of millions of people globally by making drug development quicker and more effective.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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Pursue progress , discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

Sanofi US endeavours to make our career center accessible to any and all users. If you are experiencing difficulty and need assistance applying online, please call 1-866-SANOFI2 (1-866-726-6342) or click here

US and Puerto Rico Residents Only

Sanofi Inc. and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

North America Applicants Only

The salary range for this position is:

$122,250.00 - $176,583.33

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can  be found here.

Job details

Seniority
Manager
Function
Medical Affairs
Therapeutic area
Not listed
Location
Cambridge, United States
Employment type
Full time

How this role compares

Computed from every other active Medical Affairs role in our database, not just this employer's listings.

We currently track 288 comparable Manager Medical Affairs roles across 83 biopharma companies.

288Comparable roles tracked
257Currently active
83Companies hiring similar roles
38Countries represented

Salary context

62 of 288 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $122,250/yr – $176,583/yr
Lowest disclosed · Clinical Research Associate · Pfizer $68,600/yr – $114,300/yr
Highest disclosed · Clinical Development Medical, Associate Director · Pfizer $189,200/yr – $315,400/yr
Peer group range $91,450 – $252,300 (median $198,750)

Where these roles are based

Top locations among the 288 comparable roles

United States82
Japan30
China27
China's Mainland21
India18
Germany16

+ 32 more countries

Seniority mix

288 of 288 peers have a known seniority level

Manager146
Associate Director73
Associate69

Therapeutic area mix

83 of 288 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology35
Respiratory9
Immunology7
Cardiovascular / CVRM7
Dermatology & Aesthetics7
Neuroscience6
Vaccines & Infectious Disease5
Gastroenterology4
Rare Disease2
Ophthalmology1

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Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

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Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.