IQVIA Posted October 14, 2026

Global Site Activation Manager

Centurion, South Africa Full time
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IQVIA is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Site Activation Manager, Global Study Leadership

At IQVIA, our Site Activation Managers play a critical role in bringing new therapies to patients faster. As part of the Global Study Leadership team, you'll lead site activation activities across global clinical trials, working with sponsors, sites and cross-functional teams to drive study start-up success. It's an opportunity to make a global impact while advancing your career in clinical research leadership.

Why Join Global Study Leadership?

Global Study Leadership is a global, full-service team delivering clinical trials through both therapeutically aligned and customer-dedicated delivery units. You'll work across diverse therapeutic areas and partner with leading pharmaceutical and biotechnology companies, gaining exposure to a broad range of studies, countries, regulatory environments and delivery models.

With structured career development, tailored training, mentorship and opportunities to grow across Site Activation, Clinical, Project Management, and Oversight roles, you'll build expertise that accelerates your career. Supported by a collaborative culture , flexible working environment and AI-enabled technologies, you'll help drive efficient study delivery while bringing new treatments to patients worldwide.

What You'll Be Doing

You'll lead study start-up activities across global, regional, and country-level programs, ensuring studies are activated efficiently, compliantly , and on schedule. Working as part of an integrated cross-functional team, you'll partner with sponsors, sites, and stakeholders worldwide to accelerate patient enrolment and drive successful clinical trial delivery.

Key Responsibilities  

Leading site identification, feasibility, regulatory submissions, ethics approvals and site contracting

Developing and executing Site Activation Management Plans aligned to study strategy and objectives

Performing protocol amendments

Driving study start-up timelines and critical milestones

Managing regulatory strategies, approvals and essential study documentation

Negotiating contracts and regulatory documents while ensuring local and global compliance

Identifying risks, resolving issues and implementing mitigation plans

Building strong relationships with sponsors, sites, and cross-functional stakeholders

Monitoring project metrics, budgets, timelines and performance indicators

Providing project updates, reports, presentations and operational insights

Supporting proposal development, bid defence activities and customer engagement

Mentoring colleagues and contributing to continuous improvement initiatives

What We're Looking For

Bachelor's degree in Life Sciences or a related field

Experience in site activation, study start-up, protocol amendments, regulatory affairs or clinical operations

Strong knowledge of ICH-GCP, clinical trial regulations, ethics processes and regulatory requirements

Experience managing timelines, budgets, risks and cross-functional stakeholders

Strong communication , negotiation and stakeholder management skills

Ability to lead complex projects and drive outcomes in a global environment

Strong planning, organizational and problem-solving skills

Experience working across cultures and geographies

Passion for innovation and leveraging technology to improve clinical trial delivery

Build Your Future with IQVIA

If you're looking for a role that combines global exposure, strategic influence, meaningful work, and clear career progression, we'd love to hear from you. Join a team that partners with some of the most innovative organizations in healthcare, leverages cutting-edge technology to transform clinical research and is committed to improving patient outcomes worldwide while supporting your long-term career growth.

IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more at https://jobs.iqvia.com

IQVIA is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law. We appreciate your honesty and professionalism.

Job details

Seniority
Manager
Function
Clinical Development
Therapeutic area
Not listed
Location
Centurion, South Africa
Employment type
Full time

How this role compares

Computed from every other active Clinical Development role in our database, not just this employer's listings.

We currently track 418 comparable Manager Clinical Development roles across 65 biopharma companies.

418Comparable roles tracked
395Currently active
65Companies hiring similar roles
38Countries represented

Salary context

134 of 418 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Lowest disclosed · Associate, Clinical Data Systems · AbbVie $58,656/yr – $103,500/yr
Highest disclosed · Associate Director, Clinical Development · Gilead Sciences, Inc. $210,375/yr – $272,250/yr
Peer group range $81,078 – $241,313 (median $180,500)

Where these roles are based

Top locations among the 418 comparable roles

United States194
India54
United Kingdom26
China20
Japan13
Poland11

+ 32 more countries

Seniority mix

418 of 418 peers have a known seniority level

Manager255
Associate Director114
Associate49

Therapeutic area mix

35 of 418 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology19
Immunology7
Ophthalmology2
Neuroscience2
Cardiovascular / CVRM2
Respiratory2
Dermatology & Aesthetics1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
IQVIA Centurion, South Africa Manager
Same function Same seniority Same country
60%similar
IQVIA Bloemfontein, South Africa Manager
Same function Same seniority Same country
45%similar
AbbVie Irvine, CA Manager
Same function Same seniority
45%similar
Novartis Guangzhou (Guangdong Province), China Manager
Same function Same seniority
45%similar
BMS Japan Otemachi-JP, Japan Manager
Same function Same seniority
45%similar
Bristol-Myers Squibb Business Services India Private Limited Hyderabad, India Manager
Same function Same seniority

Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

Or follow a whole field: get every new Clinical Development job in South Africa, and choose locations and companies.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Clinical Project Manager - IQVIA Biotech - Oncology
IQVIA · Centurion, South Africa · Manager
Function Therapeutic area Seniority Country
45%
Global Clinical Operations- Site Partnership Manager
Novartis · Guangzhou (Guangdong Province), China · Manager
Function Therapeutic area Seniority Country
45%
Biostatistical Programming Manager
Amgen Technology Pvt Ltd. · Hyderabad, India · Manager
Function Therapeutic area Seniority Country
45%
Manager, Statistical Programming - Starszy Programista
BMS Services Sp. z o.o. · Warsaw-WeWork-PL, Poland · Manager
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.