Horizon Therapeutics Services LLC Posted September 25, 2026

Executive Director, U.S. Brand Lead - Neurology (Rare Disease)

Deerfield, United States Full time
Marketing Neuroscience Executive/VP
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Horizon Therapeutics Services LLC is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Career Category

Marketing

Job Description

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission, to serve patients living with serious illnesses, drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

What you will do

Let's do this. Let's change the world. In this role, the Executive Director, U.S. Brand Lead - Neurology (Rare Disease) owns the U.S. commercial strategy, execution, forecast, budget, and performance for the UPLIZNA Neurology indications: generalized myasthenia gravis (gMG) and neuromyelitis optica spectrum disorder (NMOSD). The role also owns the U.S. BKEMV business and leads the BKEMV marketing team. The role was created in recognition of the increasing scope and complexity of UPLIZNA's growth drivers and the need for dedicated senior leadership for the Neurology indications. Reporting to the General Manager, Neurology & IgG4-RD, the Executive Director is a member of the Neurology & IgG4-RD Leadership Team and is accountable to the General Manager for business results.

The Executive Director owns strategy and execution for the Neurology indications, and the Neurology and BKEMV budgets. The role partners closely with the IgG4-RD brand team and other cross-indication partners to maintain a consistent UPLIZNA brand experience while addressing the needs of each indication.

Key Responsibilities include:

U.S. Business Strategy and Performance

Own the U.S. commercial strategy and annual and long-range plans for UPLIZNA in gMG and NMOSD, and BKEMV, consistent with the cross-indication strategy and direction set by the General Manager.

Own the Neurology forecast and its commercial assumptions, with inputs and support from Forecasting, Data & Analytics, and Finance.

Own the Neurology and BKEMV budgets and allocate resources against approved priorities; recommend changes in investment to the General Manager as business needs evolve.

Deliver revenue and profitability objectives by identifying growth opportunities, addressing barriers, and making timely changes to strategy, execution, targeting, channel mix, and investment.

Integrated Brand Execution

Lead development and execution of integrated brand plans across health care professional, patient and caregiver, digital and omnichannel, peer-to-peer, congress, field, access, and patient services channels.

Work closely with the Portfolio Strategy, Omnichannel and Thought Leader Liaison teams to drive integrated execution

Establish priorities, governance, decision rights, milestones, and accountability across the cross-functional brand team.

Collaborate with Sales Leadership and Training on field strategy, training, tools, messaging, and customer engagement resources; maintain a regular feedback loop between field and brand teams.

Oversee agency and vendor partners, including strategic direction, quality, resource use, and delivery of priority work.

Insights Forecasting and Optimization

Set objectives and performance measures and lead regular reviews of patient, customer, market, access, competitive, channel, and execution trends.

Partner with Brand Analytics & Insights, Market Research, Sales, TLLs, and Finance to translate data into business decisions and executive-level performance updates.

Lead scenario planning and mitigation across competitive, access, reimbursement, operational, supply, and policy considerations.

Portfolio, Access and Customer Leadership

Partner with the General Manager, IgG4-RD brand team, and cross-indication Portfolio Strategy team on UPLIZNA positioning, core messaging, customer experience, shared capabilities, and portfolio investment choices.

Partner with Market Access, Value & Access, Patient Services, and field teams to address barriers across diagnosis, referral, access, treatment initiation, and continuity of therapy.

Collaborate with Thought Leader Liaison team to ensure strategy is executed appropriately across this field-based team

Provide commercial input into evidence-generation priorities based on customer, patient, access, and competitive needs, in partnership with Medical and Value & Access and in accordance with applicable governance requirements.

Represent the U.S. Neurology business in governance forums and appropriate external engagements, and provide input to global strategy, lifecycle planning, and future growth opportunities.

BKEMV Leadership

Own U.S. BKEMV strategy, budget, performance, and cross-functional alignment within the broader Amgen biosimilars strategy.

Lead the BKEMV marketing team in navigating customer and channel dynamics, access and contracting considerations, competitive response, and value communication.

Use shared capabilities where they add value while preserving the distinct strategies, customers, and operating requirements of UPLIZNA and BKEMV.

Enterprise and People Leadership

Serve as a member of the Neurology & IgG4-RD Leadership Team and contribute to business strategy, talent, culture, and organizational effectiveness.

Lead the cross-functional brand team across Marketing, Sales, Medical, Market Access, Patient Services, Value & Access, Digital, Data & Analytics, Finance, Corporate Affairs, Regulatory, Legal, Compliance, Operations, and Global Commercial. Functional leaders retain accountability for decisions within their functions.

Build, develop, and retain an effective marketing team; set expectations, coach talent, and create development and succession opportunities.

Ensure strategies, materials, and activities comply with applicable legal, regulatory, ethical, and Amgen requirements.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The candidate we seek is an experienced leader with the following qualifications. They will also embody the Amgen leadership attributes which are:

Inspire: Create a connected, inclusive, and inspiring work environment that empowers talent to thrive

Accelerate: Enable speed that matches the urgency of patient needs by encouraging progress over perfection

Integrate: Connect the dots to amplify the collective power of Amgen to drive results for patients, staff, and shareholders

Adapt: Lead through change by adapting to an ever-changing environment and defining a clear course of action to deliver results

Basic Qualifications:

Doctorate degree and 6 years of marketing and/or commercial experience; OR

Master's degree and 10 years of marketing and/or commercial experience; OR

Bachelor's degree and 12 years of marketing and/or commercial experience; AND

6 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation of resources

Preferred Qualifications:

Progressive leadership experience in U.S. biopharmaceutical marketing, including accountability for an inline or recently launched brand in a competitive specialty market

Rare disease and/or neurology experience; experience in gMG, NMOSD, neuroimmunology, infusion-based therapies, or high-value biologics

Success accelerating post-launch growth and translating performance insights into business results

Commercial experience across health care professional and patient marketing, omnichannel engagement, field execution, market access, patient services, forecasting, analytics, and financial management

Experience owning brand budgets and forecasts, setting performance measures, prioritizing investments, and communicating business performance to senior leadership

Understanding of the U.S. payer, reimbursement, specialty distribution, buy-and-bill, and site-of-care environment relevant to rare disease therapies.

Track-record of building high-performing teams and creating strong team culture

Biosimilar commercialization experience or the ability to lead across distinct business models and markets

Experience influencing senior stakeholders in a matrixed organization.

Experience navigating medical, legal, regulatory, and compliance review processes

Advanced degree, such as an MBA

Approximately 25% travel, including overnight and occasional weekend commitments. Routine travel to Deerfield is not included in this estimate. Expected presence in Deerfield at least one week per month and additionally as needed for key meetings, team engagements, and conferences

Candidates may live anywhere in the U.S. with access to a major airport

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is $262,534 to $355,194. Actual salary will vary based on several factors including, but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

Stock-based long-term incentives

Award-winning time-off plans and bi-annual company-wide shutdowns

Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.

Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship for this role is not guaranteed.

. Salary Range

262,534.40USD -355,193.60 USD

Job details

Seniority
Executive/VP
Function
Marketing
Therapeutic area
Neuroscience
Location
Deerfield, United States
Employment type
Full time

How this role compares

Computed from every other active Marketing role in our database, not just this employer's listings.

We currently track 54 comparable Executive/VP Marketing roles across 27 biopharma companies.

54Comparable roles tracked
51Currently active
27Companies hiring similar roles
5Countries represented

Salary context

29 of 54 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Highest disclosed · Sr Director/Director, Neurology Patient Marketing (Remote, US) · Servier $251/hr – $307/hr (≈ $522,080–$638,560/yr)
Peer group range $201,550 – $580,320 (median $285,000)

Where these roles are based

Top locations among the 54 comparable roles

United States49
United Kingdom2
Canada1
Japan1
Portugal1

Seniority mix

54 of 54 peers have a known seniority level

Senior Director39
Executive/VP15

Therapeutic area mix

13 of 54 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology7
Neuroscience5
Rare Disease1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

100%similar
Karuna Therapeutics, Inc. Princeton, United States Executive/VP
Same function Same therapeutic area Same seniority Same country
100%similar
E.R. Squibb & Sons,L.L.C. Princeton, United States Executive/VP
Same function Same therapeutic area Same seniority Same country
100%similar
E.R. Squibb & Sons,L.L.C. Princeton, United States Executive/VP
Same function Same therapeutic area Same seniority Same country
90%similar
AstraZeneca Boston, Massachusetts, United States of America Senior Director
Same function Same therapeutic area Adjacent seniority Same country
90%similar
Servier Remote, United States Senior Director
Same function Same therapeutic area Adjacent seniority Same country
60%similar
Amgen USA Inc. Thousand Oaks, United States Executive/VP
Same function Same seniority Same country

Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

100%
Executive Director, Neuroscience Global Commercial Strategy
Karuna Therapeutics, Inc. · Princeton, United States · Executive/VP
Function Therapeutic area Seniority Country
90%
Senior Director, Head of Rare Neurology Thought Leader Liaisons
AstraZeneca · Boston, Massachusetts, United States of America · Senior Director
Function Therapeutic area Adjacent seniority Country
60%
Cell Therapy Strategy and Commercial Executive Director
AstraZeneca · Gaithersburg, Maryland, United States of America · Executive/VP
Function Therapeutic area Seniority Country
60%
Executive Director, Oncology Business Unit, Strategy
AstraZeneca · Gaithersburg, Maryland, United States of America · Executive/VP
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.