Vertex US Distribution Posted October 23, 2026

Senior Medical Science Liaison, Cystic Fibrosis (Great Lakes West - Iowa, Minnesota, Nebraska and Illinois)

Field Based, United States Full time
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Vertex US Distribution is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Job Description

Position Summary:

The Medical Science Liaison (MSL), with support and guidance from peers and management, will serve as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with Health Care Providers/Professionals (HCPs) to ensure the appropriate dissemination of clinical and scientific information regarding Vertex’s compounds in a timely, ethical and stakeholder-focused manner. The MSL will contribute to shaping the medical plan by providing external stakeholders' insights and contribute to the design and execution of the Medical Affairs strategy and plan. The MSL will engage HCPs in response to scientific educational and research needs with available Vertex resources and provide the latest emerging data in response to specific inquiries, as appropriate.

Key Duties/Responsibilities:

• Through scientific exchange, develops trusting relationships with a predefined list of medical and scientific Thought Leaders and other HCPs

• Applies principles of the Scientific Engagement Model (SEM) to enhance the quality of interactions as assessed by field coaching observations

• Incorporates the medical plan (i.e. listening priorities) into interactions and captures feedback in the CRM system with appropriate oversight by management, to inform internal stakeholders and assist in shaping the medical strategy

• With guidance from management, utilizes the CRM system and analytics reports to capture interaction details in a time sensitive manner and to enhance future TL engagements and manage workload

• Exchanges scientific information effectively and compliantly with external stakeholders at a proficient level of communication for both disease state and product to external stakeholders as assessed by management coaching and field observations

• Conceptual and practical knowledge of local and regional payers within the geography and understands the relationships between those plans and patient care delivery in the region

• Assists clinical development/clinical operations by understanding IB content and presenting IB content and presenting IB material at SIV meetings, providing nominations for trial sites as requested, providing end of study data reviews with investigators as needed

• With guidance from management, represents Vertex at medical congresses by providing scientific session/abstract coverage, booth staffing coverage, routine TL interactions, contributing to the daily and end of congress summaries

• After initial guidance, independently performs and completes, in a timely manner, administrative tasks such as CRM entry, vehicle mileage reporting, expense reporting, calendar entries, trainings assignments, etc. and conducts all activities in compliance with Vertex Policy and Procedures

Required Education Level:

• Minimum requirement for advanced clinical life sciences degree (NP, PA)

• Preference for terminal degree in the biomedical or life sciences (DO, MD, PharmD, PhD)

Required Experience:

• Typically requires a minimum of 1 to 2 years of experience as a MSL, in medical affairs, pharma/biotech industry, or the equivalent combination of education and experience

• Previous training or experience in designated therapeutic area is helpful

Required Knowledge/Skills:

• Ability to complete goals within allotted timeframes, and deliver high quality results

• Ability to initiate, plan and complete projects in a constantly changing field-based environment

• Ability to identify issues and create solutions

• Ability to critically appraise and comprehend medical and scientific literature

• Ability to effectively present clinical/scientific information in a credible manner in varied settings

• Good knowledge and understanding of assigned geographic territory and healthcare regulatory environment

• Ability to use Microsoft Office programs and to work in a matrix environment

• Ability to apply knowledge of relevant disease and disease management protocols, healthcare environment and competitors to articulate the medical and scientific value of Vertex products

• Demonstrated good understanding around the compliance and regulatory frameworks that govern the pharmaceutical industry and conducts compliant interactions with internal and external stakeholders.

• Possess general working knowledge of payers and unique medical information needs to support access and appropriate use of Vertex medicines

• Working knowledge of Health Economics and Outcomes Research

• Has working knowledge of local/regional payers within geography and the relationships between those plans and patient care delivery in the region

• Fluent in English & Local Language (oral and written)

Other Requirements

Indicate required certifications, licenses or specialized trainings.

• Valid driver’s license and acceptable driving record

• Ability to travel overnight up to 70%, depending on assigned geography; including occasional weekend travel

Company Information

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious and life-threatening diseases. We discovered and developed the first medicines to treat the underlying cause of cystic fibrosis (CF), a rare, life-threatening genetic disease. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases.

Founded in 1989 in Cambridge, Mass., Vertex today has research and development sites and offices around the world. For several consecutive years, Science magazine has named Vertex one of its Top Employers in the life sciences. For additional information and the latest updates from the Company, please visit www.vrtx.com.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com.

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

$171,300 - $256,900

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Job details

Seniority
Senior
Function
Medical Affairs
Therapeutic area
Not listed
Location
Field Based, United States
Employment type
Full time

How this role compares

Computed from every other active Medical Affairs role in our database, not just this employer's listings.

We currently track 372 comparable Senior Medical Affairs roles across 64 biopharma companies.

372Comparable roles tracked
357Currently active
64Companies hiring similar roles
28Countries represented

Salary context

111 of 372 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $171,300/yr – $256,900/yr
Lowest disclosed · Principal Strategic Medical Writer · AbbVie $109,500/yr – $208,500/yr
Highest disclosed · Associate Director Medical Science Liaison - East · IQVIA $230,000/yr – $280,000/yr
Peer group range $159,000 – $255,000 (median $186,375)

Where these roles are based

Top locations among the 372 comparable roles

United States212
China50
Germany16
India15
United Kingdom9
Japan9

+ 22 more countries

Seniority mix

372 of 372 peers have a known seniority level

Senior273
Associate Director84
Principal15

Therapeutic area mix

116 of 372 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology50
Neuroscience17
Rare Disease13
Dermatology & Aesthetics12
Cardiovascular / CVRM8
Immunology6
Ophthalmology3
Respiratory3
Vaccines & Infectious Disease3
Gastroenterology1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
Bayer Residence Based, United States Senior
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60%similar
Vertex US Distribution Boston, United States Senior
Same function Same seniority Same country
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60%similar
Otsuka Pharmaceutical Development and Commercialization, Inc. Remote, United States Senior
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Jazz Pharmaceuticals, Inc. Boston, United States Senior
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60%similar
AstraZeneca Cambridge, Massachusetts, United States of America Senior
Same function Same seniority Same country

Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

Or follow a whole field: get every new Medical Science Liaison job in the United States, and choose locations and companies.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Senior Medical Science Liaison, Cardiorenal (West Texas) (Residence Based, Texas, US)
Bayer · Residence Based, United States · Senior
Function Therapeutic area Seniority Country
60%
Senior Medical Science Liaison, Rare Diseases - West
Otsuka Pharmaceutical Development and Commercialization, Inc. · Remote, United States · Senior
Function Therapeutic area Seniority Country
60%
Senior Medical Science Liaison - Great Lakes Territory
Teva Pharmaceuticals · Chicago, United States · Senior
Function Therapeutic area Seniority Country
60%
Senior Medical Science Liaison - New England
Teva Pharmaceuticals · Boston, Massachusetts, United States · Senior
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.