Senior Director, Global Obesity Commercial

ROLE SUMMARY

The Senior Director, Global Obesity Commercial Development serves as a senior strategic leader responsible for shaping Pfizer’s portfolio-level commercial development strategy for the global obesity franchise. This role leads cross-functional strategic integration, drives end-to-end commercial strategy across multiple pipeline assets and indications, and partners with senior leadership on high-impact decisions.

Operating as a senior strategic leader, this role requires a high sense of urgency, the ability to navigate significant ambiguity, and the capability to fluidly shift between asset‑level detail and portfolio‑wide strategic direction. The Senior Director must demonstrate exceptional cross‑functional leadership and communication skills, orchestrating complex integrations across clinical, commercial, and operational stakeholders. As the obesity portfolio progresses toward late‑stage development and early commercialization, this position is critical in ensuring portfolio‑level strategic coherence, enterprise‑aligned decision‑making, and executional readiness across the franchise. A successful candidate will bring deep scientific and business acumen, strong strategic judgment, and a demonstrated ability to influence senior leaders and governance bodies.

ROLE RESPONSIBILITIES

Portfolio-Level Commercial Strategy Leadership

Lead the shaping of Pfizer’s overarching commercial vision and long-range portfolio strategy.

Translate market and clinical signals into portfolio-level implications and strategic choices.

Partner with R&D, Commercial, Finance, and BD to influence investment and lifecycle strategies.

Oversee forecasting frameworks and scenario planning.

Identify and shape BD opportunities.

Launch Readiness & Cross-Functional Integration

Lead global launch readiness strategy across multiple assets and indications.

Serve as senior integrator across Commercial, R&D, GAV, PGS, BD, and regions.

Shape capabilities and operating model required to deliver strategy.

Ensure alignment across global, regional, and market stakeholders.

QUALIFICATIONS

Bachelor’s degree required; advanced degree strongly preferred.

Experience

12+ years in commercial and R&D strategy, commercial development, portfolio strategy, or consulting.

Strong scientific background

Leadership shaping end-to-end strategy across multiple assets.

Strong financial acumen and experience influencing senior leadership.

Exceptional communication and executive presence.

Obesity or cardiometabolic experience strongly preferred.

LAST DAY TO APPLY: 11/12/2026

The annual base salary for this position ranges from $214,900.00 to $358,100.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 22.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.


This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.



Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations.  These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure.  Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.  Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.  If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.  Pfizer is an E-Verify employer.  This position requires permanent work authorization in the United States.

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