Jazz Pharmaceuticals, Inc. Posted November 3, 2026

Senior Director, Global Medical Director, GI Tumors

Philadelphia, United States Full time
Medical Affairs Medical Director jobs Oncology Senior Director
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Jazz Pharmaceuticals, Inc. is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

If you are a current Jazz employee please apply via the Internal Career site

Jazz Pharmaceuticals  is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases, often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit  www.jazzpharmaceuticals.com  for more information.

Job Description

The Senior Global Medical Director, Gastrointestinal Cancers is a key member of the Global Commercialization Organization Medical Affairs (GCOMA) Oncology team and reports to the VP, GCO Medical Affairs, Oncology. This is a strategic role with execution responsibilities, accountable for ensuring the needs and priorities of the US (as lead region) and EUR/INT regions are represented and addressed through engagement with key partners across Jazz. Working closely with regional Medical Affairs colleagues, the Senior Global Medical Director ensures a deep understanding of customer, patient, and healthcare system needs are represented consistently across global cross-functional discussions and decision-making forums.

The role serves as a critical interface between regional Medical Affairs teams and global R&D, Global Product Development and Commercialization functions, partnering closely with US and EUR/INT colleagues to ensure regional insights and priorities are understood, communicated, and appropriately considered within the Clinical Development Team (CDT), Late Development Team (LDT), Medical Functional Matrix Team (mFMT), and governance forums including the Product Governance Committee (PGC) and Development Project Review Committee (DPRC).

Success in this role requires strong partnership with regional teams, particularly in the US, to maintain close alignment with regional medical strategies and ensure that evidence generation activities and development plans address the needs of physicians, patients, and healthcare systems across regions.

 

Essential Functions/Responsibilities:

Lead the GI Cancer Global Medical functional matrix team

Partner closely with US and EUR/INT Medical Affairs teams to understand regional customer, patient, healthcare provider, and healthcare system needs and priorities

Represent and advocate for medical perspectives within global cross-functional teams and governance forums, including CDT, LDT, PGC, and DPRC

Contribute Medical Affairs expertise to inform early development activities, including Target Product Profile (TPP) development, clinical trial design and lifecycle planning based on regional insights and aligned future therapeutic landscape scenarios

Ensure regional needs and insights are appropriately considered in clinical development discussions, evidence-generation activities, and lifecycle planning

Maintain and apply a deep understanding of the competitive landscape to inform evidence generation strategy and internal development decisions

Lead the development, maintenance, and execution of the Integrated Evidence Generation Plan (IEGP) for Solid Tumor Oncology Product, in BTC and Gastroesophageal Cancer and other GI malignancies as assigned

Partner effectively across Medical Affairs, Clinical Development, Regulatory Affairs, Market Access, HEOR, RWE, Commercial, and other cross-functional teams to support evidence generation and scientific exchange

Lead and support evidence-generation activities, including investigator-sponsored studies, real-world evidence initiatives, health outcomes research, and Phase IV interventional studies, where appropriate

Lead the development of the breast cancer medical narrative by identifying and advancing key analytic needs and informing the interpretation of pivotal trial data

Provide Medical Affairs leadership and input into the Payor Value and Evidence Plan (GVEP)

Lead development and execution of publication strategy and evidence dissemination plan in alignment with regional evidence needs and scientific priorities

Support scientific communications, congress planning, advisory boards, and external engagement activities as required

Act as a subject matter expert for internal cross-functional stakeholders

Required Knowledge, Skills, and Abilities

A minimum of 10 years of Medical Affairs, Clinical Development, or related pharmaceutical or biotechnology industry experience is required, preferably in oncology

Experience in GI cancers and/or HER2-targeted therapies are strongly preferred

Demonstrated experience developing and executing evidence-generation strategies, publication plans, and external scientific engagement activities

Strong understanding of clinical research, evidence generation, and oncology drug development

Proven ability to influence without authority and operate effectively within complex matrix organizations

Strong strategic thinking coupled with excellent operational execution skills

Excellent written, verbal, presentation, and stakeholder management skills

Ability to build productive partnerships across regions and functions and effectively represent diverse stakeholder perspectives

Demonstrated ability to manage multiple priorities and deliver high-quality outcomes in a fast-paced environment

Experience in the lifecycle management of oncology indications strongly desired

Evidence of success in matrix organizations and track record of high performing behaviors, including independent critical thinking, initiative, and execution under time pressure with competing priorities

Self-awareness and emotional intelligence as demonstrated by prior experience navigating complex matrix environments successfully

Required/Preferred Education and Licenses

Advanced scientific or healthcare degree required (PharmD, PhD, MD, MBBS, Nurse Practitioner, PA, or equivalent)

Experience in the delivery of oncology care preferred

#LI-Remote

Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law.

FOR US BASED CANDIDATES ONLY

Jazz Pharmaceuticals, Inc. is committed to fair and equitable compensation practices and we strive to provide employees with total compensation packages that are market competitive.  For this role, the full and complete base pay range is:

$268,000.00 - $402,000.00

Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidate's expertise and contributions, within the established pay framework and our Total Compensation philosophy. Internal equity considerations will also influence individual base pay decisions. This range will be reviewed on a regular basis.

At Jazz, your base pay is only one part of your total compensation package. The successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Company's Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazz’s Long Term Equity Incentive Plan.

The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, 401k retirement savings plan, and flexible paid vacation.  For more information on our Benefits offerings please click here: https://careers.jazzpharma.com/benefits.html

Job details

Seniority
Senior Director
Function
Medical Affairs
Therapeutic area
Oncology
Location
Philadelphia, United States
Employment type
Full time

How this role compares

Computed from every other active Medical Affairs role in our database, not just this employer's listings.

We currently track 317 comparable Senior Director Medical Affairs roles across 54 biopharma companies.

317Comparable roles tracked
301Currently active
54Companies hiring similar roles
28Countries represented

Salary context

128 of 317 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $268,000/yr – $402,000/yr
Lowest disclosed · Associate Medical Director · Johnson & Johnson $137,000/yr – $235,750/yr
Peer group range $186,375 – $454,000 (median $268,425)

Where these roles are based

Top locations among the 317 comparable roles

United States223
United Kingdom25
China9
Canada7
Germany6
France6

+ 22 more countries

Seniority mix

317 of 317 peers have a known seniority level

Director255
Senior Director35
Executive/VP27

Therapeutic area mix

144 of 317 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology66
Neuroscience19
Immunology18
Cardiovascular / CVRM9
Dermatology & Aesthetics9
Rare Disease7
Gastroenterology6
Respiratory6
Vaccines & Infectious Disease2
Ophthalmology2

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

100%similar
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Same function Same therapeutic area Same seniority Same country
100%similar
E.R. Squibb & Sons,L.L.C. Princeton, United States Senior Director
Same function Same therapeutic area Same seniority Same country
100%similar
Jazz Pharmaceuticals, Inc. Pa, United States Senior Director
Same function Same therapeutic area Same seniority Same country
100%similar
Jazz Pharmaceuticals, Inc. Philadelphia, United States Senior Director
Same function Same therapeutic area Same seniority Same country
100%similar
Jazz Pharmaceuticals, Inc. Pa, United States Senior Director
Same function Same therapeutic area Same seniority Same country
90%similar
AbbVie Director
Same function Same therapeutic area Adjacent seniority Same country

Open in 3 locations

Mettawa, United StatesSan Francisco, United StatesFlorham Park, United States

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How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

100%
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Function Therapeutic area Seniority Country
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Function Therapeutic area Seniority Country
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Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.