Principal Research Scientist I – Analytical Development – PDST – Late-Stage Process Analytics
About this opportunity
Company Description
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube.
Job Description
The Principal Scientist I will be an integral part of the Process Analytics team in the Operations – Product Development Science and Technology – Biologics division. The role involves leading analytical activities within a high-throughput testing group supporting biologics products with a focus on advancing AbbVie’s late-stage clinical programs. This position calls for an individual with a strong technical analytical background, demonstrated leadership and organizational skills and the ability to effectively communicate and work cross-functionally.
Responsibilities:
Lead analytical activities within a high-throughput testing group supporting biologics process development for late-stage programs.
Serve as the subject matter expert for separation-based methods, including HPLC and capillary electrophoresis.
Evaluate and select effective fit for purpose analytical technologies and methods to meet process development needs.
Provide expertise and support for method development, execution, and troubleshooting. Provide direct technical guidance and oversight to scientists executing sample testing with hands on lab support when needed.
Partner with process development SMEs for interpretation and understanding of analytical data.
Oversee sample testing schedule and prioritization; drive timely delivery of high-quality testing results.
Support implementation of automation and high-throughput experimentation workflows.
Drive continuous improvement initiatives to enhance lab efficiency and capability.
Mentor, train and supervise junior scientists.
Qualifications
PhD in chemistry, biology, biochemistry, chemical engineering, or related technical discipline with 6+ years of relevant professional experience working in analytical development or process analytics; MS degree with minimum of 10+ years of relevant experience.
Proven experience leading analytical development activities for biologics development, including mAbs, multi-specifics, antibody-drug conjugates, and fusion proteins.
Hands on method development experience in protein and impurity analysis techniques such as HPLC, capillary electrophoresis, and other relevant methods for biologics required. Experience with mass spectrometry and ELISA is a plus.
Previous experience with automation is a plus.
Highly organized with ability to multitask and drive efficient workflows.
Ability to think critically and demonstrate troubleshooting and problem-solving skills.
Strong people leadership skills and demonstrated ability to foster an engaging, inclusive and collaborative team environment. Direct people management experience required.
Excellent communication and interpersonal skills. Ability to work effectively across functions, anticipating and addressing overall program development needs.
An independent, self-motivated, proactive individual who thrives in a fast-paced team environment.
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our long-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html
Job details
How this role compares
Computed from every other active Manufacturing & CMC role in our database, not just this employer's listings.
We currently track 683 comparable Principal Manufacturing & CMC roles across 89 biopharma companies.
Salary context
264 of 683 peers report a salary range (USD, annualized)
Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.
Where these roles are based
Top locations among the 683 comparable roles
+ 28 more countries
Seniority mix
683 of 683 peers have a known seniority level
Therapeutic area mix
9 of 683 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden
Similar opportunities
The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.
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How we calculate "similar"
No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.
Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.
0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.