Regeneron Pharmaceuticals, Inc (USA) Posted August 1, 2026

Principal Project Engineer

Renss, United States Full time
Notify me about similar jobs

Regeneron Pharmaceuticals, Inc (USA) is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Build our future together:

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Senior Project Engineer to join our growing Project Engineering team. In this role, you will design, specify, and commission new and renovated process and clean utility equipment. You will lead deviation investigations and provide engineering support across manufacturing processes. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & where:

Location: Troy, New York, United States

Work model: Onsite Monday-Friday 8:00am-4:30pm

Travel: up to 10%, domestic and international

Discover your role:

Design and specify cGMP process equipment, piping, and controls, including engineering documentation

Manage mid-to-large projects for process equipment and clean utilities, including start-up, commissioning, and site acceptance

Lead design review and installation of equipment

Prepare piping and instrumentation diagrams and develop Process Flow Diagrams

Support QA/Validation with design documents and protocol execution

Investigate process equipment, utility, and control system anomalies, implementing corrective and preventive actions

Supervise mechanical, electrical, and automation contractors

This role requires:

Bachelor's degree in Chemical Engineering, Biochemical Engineering, or another relevant Engineering discipline, and the following amount of project/process engineering experience for each level :

Senior Project Engineer - 5+ Years

Principal Project Engineer - 8+ Years

Level will be determined based on qualifications relevant to the role

Direct experience with biopharmaceutical process equipment is preferred

Solid understanding of process control systems and automation.

Thorough knowledge of engineering documentation for cGMP process equipment and sanitary equipment design requirements

Experience planning and tracking project activities and schedules

Strong interpersonal and cross-cultural communication skills, with the ability to lead without direct authority

Gowning and Physical Requirements:

Full cleanroom attire (Examples may include: including laundered undergarments, gown, facemask, hairnet, safety glasses, safety shoes and booties, latex gloves and the use of sanitizing agents during gowning process including IPA)

Ability to remove jewelry, make-up and nail adornments when wearing cleanroom attire

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all  qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate.  The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits.  Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/ . For other locations, additional information will be provided during the recruitment process.  If you have any questions, please speak with your recruiter.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)

$88,300.00 - $168,500.00

Job details

Seniority
Principal
Function
Manufacturing & CMC
Therapeutic area
Not listed
Location
Renss, United States
Employment type
Full time

How this role compares

Computed from every other active Manufacturing & CMC role in our database, not just this employer's listings.

We currently track 684 comparable Principal Manufacturing & CMC roles across 89 biopharma companies.

684Comparable roles tracked
621Currently active
89Companies hiring similar roles
34Countries represented

Salary context

265 of 684 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $88,300/yr – $168,500/yr
Lowest disclosed · Senior Technician Calibration - Maintenance · Mylan Technologies, Inc. $37,000/yr – $80,000/yr
Peer group range $58,500 – $288,000 (median $154,900)

Where these roles are based

Top locations among the 684 comparable roles

United States452
India38
Ireland33
Netherlands23
Germany15
Switzerland14

+ 28 more countries

Seniority mix

684 of 684 peers have a known seniority level

Senior431
Principal138
Director115

Therapeutic area mix

9 of 684 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Vaccines & Infectious Disease4
Oncology3
Respiratory1
Dermatology & Aesthetics1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
Merck Rahway, New Jersey, United States of America Principal
Same function Same seniority Same country
60%similar
AbbVie North Chicago, IL Principal
Same function Same seniority Same country
60%similar
AbbVie North Chicago, IL Principal
Same function Same seniority Same country
60%similar
AbbVie Pleasanton, CA Principal
Same function Same seniority Same country
60%similar
Sanofi US Services Inc. Waltham, United States Principal
Same function Same seniority Same country
60%similar
Regeneron Pharmaceuticals, Inc (USA) Tarrytown, United States Principal
Same function Same seniority Same country

Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

Or follow a whole field: get every new Manufacturing & CMC job in the United States, and choose locations and companies.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Principal Scientist/Engineer, Drug/Device Combination Products - Device Characterization
Merck · Rahway, New Jersey, United States of America · Principal
Function Therapeutic area Seniority Country
60%
Principal Scientist I, Biologics Drug Product Development
AbbVie · North Chicago, IL · Principal
Function Therapeutic area Seniority Country
60%
Principal Scientist, Biologics Drug Product Development (DPDT)
Regeneron Pharmaceuticals, Inc (USA) · Tarrytown, United States · Principal
Function Therapeutic area Seniority Country
60%
Senior Principal Microbiologist
Lilly · Concord, North Carolina, United States of America · Principal
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.