AbbVie Posted September 18, 2026

Principal Data Architect II, Biotherapeutics and Genetic Medicine

Worcester, MA Full-time
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AbbVie is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at  www.abbvie.com . Follow @abbvie on  LinkedIn,   Facebook ,  Instagram ,  X  and  YouTube.

Job Description

Overview :

Biotherapeutics and Genetic Medicine (BGM) sits within AbbVie’s Discovery Research organization and supports discovery and optimization across biotherapeutic and genetic medicine modalities, including monoclonal antibodies, multispecifics, proteins, conjugates, AAV, LNPs, and siRNA.

The Principal Data Architect will shape the cloud-native data foundation that enables predictive and generative AI/ML solutions in discovery scientist workflows. This role owns the architecture, adoption, and continuous improvement of a scalable data platform that connects laboratory data across dozens of assays, supports machine learning development and deployment, and improves how scientific data is used across the organization.

The position reports to the Head of AI/ML in BGM and serves as a trusted advisor to senior leadership. This is a technical leadership role on the individual contributor track, with potential to expand into people management in the future. It requires close partnership with wet lab scientists, ML engineers, software engineers, data engineers, automation teams, and data governance partners. The role is central to building a robust, resilient, and scalable data foundation for BGM’s AI/ML strategy.

Responsibilities

Define and drive the architecture for a scalable, cloud-native data platform that supports AbbVie’s AI/ML strategy in BGM.

Design data models and integration patterns that connect datasets generated across multiple lab groups and establish certified datasets for downstream scientific, operational, and machine learning use.

Partner with wet lab scientists and automation engineers to maximize the value of data captured through lab automation workflows.

Work with data scientists and deployment engineers to ensure data pipelines support both model development and production deployment.

Advance FAIR data practices and data stewardship in alignment with BGM strategic priorities.

Champion connected data, data-as-a-product, and cloud-first architecture principles across the organization.

Partner with data infrastructure and governance experts to ensure data policies are implemented effectively.

Align BGM data infrastructure initiatives with broader AbbVie efforts such as Convergence and ARCH.

Communicate platform impact through user stories, metrics, and KPIs that show the value of the data platform to AbbVie’s therapeutic program pipeline.

Qualifications

MS with 14+ years’ or PhD with 8+ years’ in machine learning, computer science, applied mathematics, data science, computational biology, or a closely related field.

6+ years of experience in data architecture after completion of graduate studies, with a track record of designing enterprise data platforms

Graduate degree in computer science, data science, computational biology, computational chemistry, computational biophysics, or a related field.

Experience designing enterprise data platforms.

Strong technical skills in data modeling, data integration, data storage solutions, data pipelines, and AI/ML integration.

Production programming experience in SQL, Python, or Java.

Experience building cloud data infrastructure on AWS, Azure, or GCP.

Ability to work across wet lab and dry lab scientific workflows.

Experience collaborating across functions and building stakeholder alignment.

Strong communication and interpersonal skills.

Ability to apply data governance principles in day-to-day decision-making.

Experience in the pharmaceutical or biotechnology industry.

Preferred:

Experience leading cross-functional technical teams across reporting lines and multiplying their impact through best practices.

Experience working in large, cross-functional R&D environments.

Work Environment:

Hybrid role based in Worcester, MA.

On-site presence required 3 days per week.

This is an individual contributor role.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. ​

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.​

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit  https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Job details

Seniority
Principal
Function
Information Technology
Therapeutic area
Not listed
Location
Worcester, MA
Employment type
Full-time

How this role compares

Computed from every other active Information Technology role in our database, not just this employer's listings.

We currently track 577 comparable Principal Information Technology roles across 55 biopharma companies.

577Comparable roles tracked
535Currently active
55Companies hiring similar roles
32Countries represented

Salary context

106 of 577 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $141,500/yr – $268,500/yr
Highest disclosed · Director, Product Management · $260,000/yr – $305,200/yr
Peer group range $98,050 – $282,600 (median $188,775)

Where these roles are based

Top locations among the 577 comparable roles

United States221
India207
Spain27
Poland21
United Kingdom18
Philippines11

+ 26 more countries

Seniority mix

577 of 577 peers have a known seniority level

Senior406
Principal103
Director68

Therapeutic area mix

5 of 577 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology4
Vaccines & Infectious Disease1

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The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

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How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

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Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.