Global HEOR Evidence Synthesis Manager
About this opportunity
Career Category
Operations
Job Description
Department: Global Health Economics & Outcomes Research (HEOR)
Job Family: Evidence Synthesis
Job Type: Full-Time
Location: Hyderabad, India
Reports To: Global HEOR Evidence Synthesis Team Lead
Position Summary
The Global HEOR Evidence Synthesis Manager plays a critical role in supporting Amgen’s global market access and health economics strategy through contributing statistical capabilities and methodological leadership for evidence synthesis methodologies (meta-analyses & ITCs). The Evidence Synthesis Manager will conduct different evidence pooling analyses ranging from meta-analyses, network meta-analyses to population-adjusted indirect treatment comparisons (MAICs and STCs) and health-economic analyses facilitating HTA and payer decision-making.
Educational Qualifications
A Bachelor’s, Master's or Doctoral-level degree in applied statistics, biostatistics, mathematics, operations research, engineering, health economics, pharmacy, and related quantitative fields
Required experience/ knowledge
Years of relevant experience in evidence synthesis and statistical analyses in the pharmaceutical, biotech or consulting setting: +6 years for Master’s degree and +8 years for Bachelor’s degree.
Hands-on experience in research design and statistical methods, including estimating survival, pooled treatment effects and other methods to estimate treatment effect
Experience in conducting health economic analyses such as cost-effectiveness/cost-utility (e.g., markov, partitioned survival model), cost minimization, budget impact, and other techniques, as appropriate
Proficiency with modeling and statistical tools such as Excel, WinBugs, OpenBugs, JAGS, R or Python.
Familiarity with AI/ML techniques and Bayesian statistics is a plus.
Key Responsibilities
Design and conduct advanced evidence synthesis and statistical analyses such as Pairwise Meta-Analysis, Surrogate outcome assessment, Survival analysis, External Control Arm (ECA) analysis, Indirect treatment comparison (ITCs), Network Meta-Analysis, Match adjusted indirect treatment analysis (MAIC), Simulated treatment comparison (STC) and Meta-regression
Design and develop health economic models for products at all stages of development and launch, using cost-effectiveness/cost-utility (e.g., markov, partitioned survival model), cost minimization, budget impact, and other techniques, as appropriate.
Ensure quality standards are adhered to in all analyses and new methodologies and techniques are adequately assessed and implemented.
Plan and conduct statistical analyses of clinical trials, RWE and other relevant data sources and develop supporting technical documentation for statistical analyses and economic models.
Monitor and integrate evolving HTA guidelines, payer requirements, and methodological advancements.
Create QC checklists and establish robust QC processes across projects
To proactively mentor and develop members of the team
Skills & Competencies
Excellent English oral and written communication, with ability to tailor content to different stakeholders.
Strong quantitative and analytical skills with attention to detail.
Strong project management and time-management abilities.
Innovative use of artificial intelligence to boost efficiency.
Organizational Behaviors
Effective cross-functional collaboration and interpersonal skills.
Proactive, independent, and detail-oriented approach to problem-solving.
Comfortable working in a global team across time zones and cultures.
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Job details
How this role compares
Computed from every other active Clinical Development role in our database, not just this employer's listings.
We currently track 324 comparable Manager Clinical Development roles across 67 biopharma companies.
Salary context
84 of 324 peers report a salary range (USD, annualized)
Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.
Where these roles are based
Top locations among the 324 comparable roles
+ 21 more countries
Seniority mix
324 of 324 peers have a known seniority level
Therapeutic area mix
32 of 324 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden
Similar opportunities
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How we calculate "similar"
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Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.
0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.