Executive Director, Pharmacology and Toxicology (Suzhou, JS, CN, 215123)

苏州，中国   |   全职   |   Job ID: 11909

About the role:

As Senior/Executive Director, Pharmacology and Toxicology, you will lead preclinical work that helps advance promising drug candidates toward clinical development and supports BioNTech’s mission to develop innovative medicines. You’ll guide an integrated team across in vivo pharmacology, toxicology, and drug metabolism and pharmacokinetics.

Working with colleagues across discovery, translational medicine, clinical, and regulatory functions, you’ll connect evidence from efficacy, exposure, and safety studies to strengthen candidate selection and development readiness.

Your contribution:

Lead and develop a 10–15-person team across in vivo pharmacology, toxicology, and drug metabolism and pharmacokinetics

Direct efficacy, pharmacokinetic and pharmacodynamic, biodistribution, and mechanism-of-action studies to guide candidate selection

Design and interpret toxicology and drug metabolism and pharmacokinetics studies in rodents and non-human primates to assess safety and development potential

Integrate efficacy, biomarker, exposure, and safety data to inform progression decisions, dose selection, and clinical readiness

Shape regulatory-aligned, submission-ready nonclinical packages and partner across functions and with external organizations to deliver them

Build robust study workflows and decision standards, while mentoring your team and representing the function in governance and scientific discussions

A good match:

An advanced degree in pharmacology, toxicology, pharmaceutical sciences, veterinary medicine, immunology, oncology biology, or a related discipline; postdoctoral training or toxicology board certification is preferred

A track record advancing multiple drug candidates from discovery through studies that support regulatory submissions and clinical trials

Experience leading multidisciplinary teams across in vivo pharmacology, toxicology, and drug metabolism and pharmacokinetics

Strong skills in designing and interpreting efficacy, pharmacokinetic and pharmacodynamic, toxicology, safety pharmacology, and drug metabolism studies in rodents and non-human primates

Knowledge of disease-relevant models, exposure-response analysis, translational biomarkers, repeat-dose toxicology, toxicokinetics, immunogenicity, and global nonclinical requirements

The ability to guide external research partners, raise scientific and regulatory standards, and bring teams together around clear preclinical decisions

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我们诚挚期待您的加入。