Exelixis Inc Posted August 26, 2026

Associate Principal IT Product Lead - Digital Applications

Alameda, United States Full time
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Exelixis Inc is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

SUMMARY/JOB PURPOSE

The Associate Principal IT Product Lead - Digital Applications, will lead a portfolio of digital products critical to Exelixis's success and ambition to launch innovative medicines for patients. This role is pivotal in driving the strategy, development, and operational excellence of our digital application ecosystem, ensuring alignment with business objectives and a strong focus on user experience and value delivery. Operating within a product-centric model, the Associate Principal IT Product Lead will be responsible for defining product roadmaps, fostering cross-functional collaboration, and leading agile product teams to deliver innovative and impactful digital solutions that accelerate drug discovery, development, and commercialization.

ESSENTIAL DUTIES/RESPONSIBILITIES

Product Strategy & Roadmap (Product-Centric Focus): Own a portfolio of products coupled with the development and execution of the vision, strategy, and roadmap for inscope digital products within the Digital Applications job family.

Partner with senior product leads and business stakeholders to gather insights, understand user needs, and translate them into clear product requirements and user stories.

Lead and drive market research, competitive analysis, and technology assessments to inform product planning and identify innovation opportunities.

Engage and lead in the prioritization of product initiatives by evaluating business impact, technical feasibility, compliance needs, and resource constraints.

Own the architecture and design of a portfolio of products and ensure digital solutions are aligned and built securely and comply with enterprise standards.

Product Development & Delivery (Agile/Product Team Leadership): Own the management of the product lifecycle from ideation through launch and post-launch optimization, applying Agile methodologies (e.g., Scrum, Kanban) to ensure efficient delivery to a portfolio of Digital Products.

Ensure the user stories, acceptance criteria, and product specifications are well defined and are aligned with the product vision and business objectives to a portfolio of digital products

Lead the partnerships with engineering, architecture, and quality assurance teams to help ensure timely delivery of scalable, secure, and high-quality portfolio of digital applications.

Lead the coordination with external vendors and service providers to support alignment on product roadmaps and delivery operations to a portfolio of digital products

Promote user-centric design by incorporating user research, usability testing, and feedback into product enhancements to a portfolio of digital products

Support the Principal Product Lead in mentoring other digital application team members, encouraging a culture of ownership, innovation, and continuous improvement.

Stakeholder Management & Cross-Functional Collaboration: Act as a key liaison between IT and business functions, helping to translate technical concepts into business language and vice versa across multiple functional areas.

Build collaborative relationships with stakeholders to support alignment of product vision, priorities, and outcomes across two or more functional areas.

Facilitate communication and coordination across product, business, and IT teams to support effective decision-making.

Own and drive the digital products roadmap in cross-functional discussions and contribute to strategic initiatives as needed.

Operational Excellence, Quality & Compliance: Lead the support efforts to maintain the operational stability, performance, and security of digital applications in collaboration with IT operations and infrastructure teams.

Lead the vendor relationships and third-party software solutions that support the digital application portfolio.

Lead compliance with regulatory requirements (e.g., GxP, HIPAA, GDPR) and internal quality and security standards across product releases.

Accountability to quality assurance processes to ensure product releases meet defined standards to two or more Digital Products.

Actively contribute to the Implementation and maintenance of robust data management & AI practices to protect sensitive information and ensure its accuracy and reliability.

Track and report on key performance indicators (KPIs) to assess product success, adoption, and business impact, and support continuous improvement efforts.

Performs other duties as assigned

Complies with all policies and standards

SUPERVISORY RESPONSIBILITIES

No supervisory responsibilities.

EDUCATION/EXPERIENCE/KNOWLEDGE/SKILLS & ABILITIES

Education

Bachelor’s degree in related discipline and 11 years of related experience; or

Master's degree in mathematics or statistics or engineering, and 9 years of related experience.

PhD degree in a related discipline and 5 years of related experience; or

Equivalent combination of education and experience.

Experience

Minimum of 6 years of experience supporting Enterprise IT enabling business functions.

Minimum of 8+ years of progressive experience in IT, with at least 6+ years in a leadership role focused on digital applications or product management within the life science or pharmaceutical industry.

Proven experience leading product development teams in an agile/product-centric operating model is essential.

Strong understanding of the drug discovery or clinical development, or commercialization lifecycle within a pharmaceutical or biotechnology company.

Demonstrated success in defining and delivering complex digital products that drive significant business value.

Experience with one of the mentioned specific technologies or platforms as relevant to the specific role, [e.g., SaaS platforms (Veeva, SalesForce) or cloud solutions (AWS, Azure), or functional capabilities specific to business function such as LIMS, SAP ERP, EDC, CTMS, CRM systems widely used in pharma].

Experience with regulatory frameworks and compliance in a GxP environment.

Experience with Salesforce Marketing Cloud configuration, deployment, and implementation is preferred.

Experience in implementing and supporting MarTech applications within the pharmaceutical industry is preferred.

Knowledge, Skills and Abilities

Required:

Exceptional leadership and team-building skills, with the ability to inspire and motivate diverse teams.

Strong strategic thinking and problem-solving abilities, with a data-driven approach to decision-making.

Excellent communication, presentation, and interpersonal skills, with the ability to influence and collaborate effectively at all levels of the organization.

Deep understanding of product management methodologies (e.g., Agile, Scrum, Kanban) and product lifecycle management.

Solid technical acumen with the ability to understand complex IT architectures and development processes.

Ability to manage multiple priorities in a fast-paced, dynamic environment.Occasional travel may be required to other company sites, conferences, or vendor locations.

Travel Requirements

Occasional travel (5–10%) may be required to other company sites, conferences, or vendor locations.

Environmental Requirements:

Our office is a modern, open-plan space that fosters collaboration and creativity.

Teams work closely together, sharing ideas and solutions in a supportive atmosphere.

We provide all necessary equipment, including dual monitors and ergonomic chairs, to ensure a comfortable workspace.

On-call availability for critical escalations.

#LI-EZ1

Our compensation reflects the cost of labor across several U.S. geographic markets, and we pay differently based on those defined markets. The base pay range for this position is $174,000 - $246,000 annually. The base pay range may take into account the candidate’s geographic region, which will adjust the pay depending on the specific work location. The base pay offered will take into account the candidate’s geographic region, job-related knowledge, skills, experience and internal equity, among other factors.

In addition to the base salary, as part of our Total Rewards program, Exelixis offers comprehensive employee benefits package, including a 401k plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Employees are also eligible for a discretionary annual bonus program, or if field sales staff, a sales-based incentive plan. Exelixis also offers employees the opportunity to purchase company stock, and receive long-term incentives, 15 accrued vacation days in their first year, 17 paid holidays including a company-wide winter shutdown in December, and up to 10 sick days throughout the calendar year.

If you have a disability and need an accommodation in relation to the recruiting process, please email us at: ApplicantAccommodations@exelixis.com .

WORKING CONDITIONS:

Our office is a modern space that fosters collaboration and creativity. Teams work closely together, sharing ideas and solutions in a supportive atmosphere. We provide all necessary equipment, including dual monitors and ergonomic chairs, to ensure a comfortable workspace.

DISCLAIMER: 

The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification.  It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.

We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class.

Job details

Seniority
Principal
Function
Information Technology
Therapeutic area
Not listed
Location
Alameda, United States
Employment type
Full time

How this role compares

Computed from every other active Information Technology role in our database, not just this employer's listings.

We currently track 404 comparable Principal Information Technology roles across 44 biopharma companies.

404Comparable roles tracked
368Currently active
44Companies hiring similar roles
21Countries represented

Salary context

54 of 404 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $174,000/yr – $246,000/yr
Highest disclosed · Director, AI and Agentic Engineering · Exelixis Inc $215,000/yr – $306,000/yr
Peer group range $98,050 – $260,500 (median $157,822)

Where these roles are based

Top locations among the 404 comparable roles

India208
United States94
Spain26
Poland17
Greece11
Portugal9

+ 15 more countries

Seniority mix

404 of 404 peers have a known seniority level

Senior305
Principal66
Director33

Therapeutic area mix

1 of 404 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Vaccines & Infectious Disease1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
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Regeneron Pharmaceuticals, Inc (USA) Renss, United States Principal
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60%similar
Regeneron Pharmaceuticals, Inc (USA) Tarrytown, United States Principal
Same function Same seniority Same country

Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Principal Software Development Engineer
Roche · Santa Clara, California, United States of America · Principal
Function Therapeutic area Seniority Country
60%
Principal Automation Systems Administrator, Manufacturing & Lab Support
Regeneron Pharmaceuticals, Inc (USA) · Renss, United States · Principal
Function Therapeutic area Seniority Country
60%
Principal Business Analyst - Velocigene
Regeneron Pharmaceuticals, Inc (USA) · Tarrytown, United States · Principal
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Principal Business Analyst – Science Data Portal
Regeneron Pharmaceuticals, Inc (USA) · Tarrytown, United States · Principal
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.