Senior Manager, AI, and Data Engineering

Pfizer Oncology is building an AI-first R&D engine where artificial intelligence is a foundational capability shaping how medicines are discovered, developed, and delivered to patients. We are seeking AI & Data Engineers to focus on generalist, use case driven AI solutions where process, workflow, and data engineering are as critical as advanced science. This role is ideal for engineers who thrive in rapid prototyping environments and enjoy translating real-world problems into practical, AI enabled tools.

In this role, you will partner with scientific, clinical, and operational teams to develop data pipelines, analytics, and machine learning solutions that enhance the effectiveness of Oncology R&D workflows.

Key Responsibilities

Build and prototype AI enabled solutions supporting Oncology R&D workflows and decision making.

Develop and maintain data pipelines, feature engineering workflows, and analytical models.

Apply machine learning techniques to structured and unstructured healthcare data.

Collaborate with scientific and product partners to understand needs and deliver usable tools.

Focus on speed, iteration, and usability, with production scaling supported by enterprise Digital teams as appropriate.

Contribute to shared engineering standards, documentation, and best practices.

Basic Qualifications

Bachelor's degree and 6+ years of relevant work experience OR Master’s degree and 5+ years of experience OR PhD and 1+ years of experience. Advanced degree in computer science, machine learning, artificial intelligence, computational biology, bioinformatics, statistics, engineering, or a related quantitative or scientific field strongly preferred.

Demonstrated hands‑on experience building data, analytics, or ML solutions in healthcare, life sciences, or health tech.

Strong programming skills and experience with modern data and ML tooling.

Ability to rapidly prototype and adapt solutions based on feedback.

Strong collaboration and communication skills.

Preferred Qualifications

Experience working on research or clinical workflows.

Background in healthcare technology companies or AI startups.

Exposure to cloud‑based data and ML environments.


The annual base salary for this position ranges from $139,100.00 to $231,900.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.



This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.


 Relocation assistance may be available based on business needs and/or eligibility.


 Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.


 Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations.  These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure.  Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.  Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.  If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.


 EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.  Pfizer is an E-Verify employer.  This position requires permanent work authorization in the United States.

Pfizer endeavors to make   www.pfizer.com/careers   accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email   disabilityrecruitment@pfizer.com . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.


 To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on  Pfizer Careers .


Research and Development