Exelixis Inc Posted September 11, 2026

Staff Engineer - DevSecOps

Remote, United States Full time
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Exelixis Inc is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

SUMMARY/JOB PURPOSE

The Staff Engineer - DevSecOps is responsible for protecting the organization's AI infrastructure, data, and systems from internal and external cybersecurity threats by implementing, managing, and continuously improving security practices, tools, and operations with a focus on AI, cloud applications, and infrastructure.

ESSENTIAL DUTIES/RESPONSIBILITIES

Build AI-assisted development tools, such as coding copilots or agentic coding tools.

Design, implement, and continuously improve security solutions, AI guardrails, and procedures.

Improve the organization's security posture by identifying weaknesses and vulnerabilities in its security infrastructure and implementing traditional and AI centric solutions to address them.

Integrate with various teams on technology initiatives to improve security of our applications, cloud, and AI infrastructure.

Assist in investigating and responding to security events and incidents, such as malware infections, unauthorized access attempts, and other potential security breaches.

Determine best procedures to contain threats, document findings, and escalate issues as needed.

Monitor and analyze security logs and events from various sources.

Stay current with the latest threat landscape, emerging trends, and solutions in AI and cybersecurity to proactively identify and mitigate potential security risks.

Improve the organization's security posture by identifying weaknesses and vulnerabilities in its security infrastructure and implementing solutions to address them.

Assist with and provide cyber expertise to internal staff, vendors, and partners on security practices and issues.

Follow industry and Exelixis best practices and procedures in a SOX and an FDA regulated environment.

Performs other duties as assigned

Complies with all policies and standards

SUPERVISORY RESPONSIBILITIES

No supervisory responsibilities.

EDUCATION/EXPERIENCE/KNOWLEDGE/SKILLS & ABILITIES

Education

Bachelor’s degree in related discipline and 7 years of related experience; or

Master’s degree in related discipline and 5 years of related experience; or

Equivalent combination of education and experience

CISSP, CISM, CEH, OSCP, GIAC or similar cybersecurity certification preferred

Experience

Experience with operation and implementation of cybersecurity tools.

Experience in designing, implementing, and managing security controls within cloud platforms, such as IAM, VPC, Zero Trust principles, IaC, IAAS, Security Groups, Key Management Services, SDLC, Ci/Cd pipelines and Network Security.

Experience in IT Security or related infrastructure administration role in an enterprise environment. Technical lead experience is preferred.

Experience in investigations and response to cyber events and incidents.

Experience in enhancing organizational security awareness and resilience.

Experience with cloud, system, and application security.

Experience administering IT systems.

Experience working in Agile environments and using ticketing systems (e.g., JIRA, JSM).

Experience in regulated industries (e.g., biotech, pharma) with knowledge of GxP and SOX compliance preferred.

Knowledge, Skills and Abilities

Required:

Strong knowledge of general IT applications and infrastructure.

Advanced knowledge of CLI and scripting language experience (Python, PowerShell, etc..)

Advanced knowledge of AWS

Advanced knowledge of IAC, SDLC, Ci/Cd pipelines

Advanced knowledge of cybersecurity technologies and concepts.

Strong analytical, problem solving, organizational, and communication skills.

Ability to work effectively with customers to solve business challenges while balancing the need for confidentiality, integrity, and availability.

Ability to multitask and work collaboratively.

Ability to work with ambiguity.

Ability to work with confidential data.

Ability to continuously learn and improve.

Ability to work with minimal guidance, to adapt to frequent priority changes, and response to ad-hoc requests

Travel Requirements

5% Occasional travel (5%).

Environmental Requirements:

Our office is a modern, open space that fosters collaboration and creativity.

Teams work closely together, sharing ideas and solutions in a supportive atmosphere.

We provide all necessary equipment, including dual monitors and ergonomic chairs, to ensure a comfortable workspace.

On-call availability for critical escalations.

#LI-EZ1

Our compensation reflects the cost of labor across several U.S. geographic markets, and we pay differently based on those defined markets. The base pay range for this position is $148,000 - $210,500 annually. The base pay range may take into account the candidate’s geographic region, which will adjust the pay depending on the specific work location. The base pay offered will take into account the candidate’s geographic region, job-related knowledge, skills, experience and internal equity, among other factors.

In addition to the base salary, as part of our Total Rewards program, Exelixis offers comprehensive employee benefits package, including a 401k plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Employees are also eligible for a discretionary annual bonus program, or if field sales staff, a sales-based incentive plan. Exelixis also offers employees the opportunity to purchase company stock, and receive long-term incentives, 15 accrued vacation days in their first year, 17 paid holidays including a company-wide winter shutdown in December, and up to 10 sick days throughout the calendar year.

If you have a disability and need an accommodation in relation to the recruiting process, please email us at: ApplicantAccommodations@exelixis.com .

WORKING CONDITIONS:

Our office is a modern space that fosters collaboration and creativity. Teams work closely together, sharing ideas and solutions in a supportive atmosphere. We provide all necessary equipment, including dual monitors and ergonomic chairs, to ensure a comfortable workspace.

DISCLAIMER: 

The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification.  It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.

We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class.

Job details

Seniority
Not listed
Function
Information Technology
Therapeutic area
Not listed
Location
Remote, United States
Employment type
Full time

How this role compares

Computed from every other active Information Technology role in our database, not just this employer's listings.

We currently track 1376 comparable Information Technology roles across 76 biopharma companies.

1376Comparable roles tracked
1216Currently active
76Companies hiring similar roles
35Countries represented

Salary context

182 of 1376 peers report a salary range (USD, annualized)

Peers share this role's job function. This posting doesn't list a seniority level, so peers aren't narrowed by seniority either -- the range below may span more levels than usual.

This roleSubject $148,000/yr – $210,500/yr
Lowest disclosed · 2027 Business Technology Solutions Intern - Data & Software Engineering (Undergraduate) · AbbVie $21/hr – $37/hr (≈ $43,680–$76,960/yr)
Peer group range $60,320 – $400,000 (median $172,050)

Where these roles are based

Top locations among the 1376 comparable roles

India604
United States318
Spain132
Poland95
Portugal27
China21

+ 29 more countries

Seniority mix

693 of 1376 peers have a known seniority level

Senior293
Manager173
Principal59
Associate Director51
Associate48
Director38
Intern/Fellow/Postdoc14
Senior Director14
Executive/VP3

Therapeutic area mix

1 of 1376 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Vaccines & Infectious Disease1

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The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

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Notify me about similar jobs

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How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

40%
Technical Lead - Software Developer, Data Foundry
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Function Therapeutic area Seniority Country
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Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.