Sr. Scientist, In-Vivo Pharmacology
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About Superluminal Medicines
Superluminal Medicines is a generative biology and chemistry company revolutionizing the speed and accuracy of how small molecule medicines are created. The Company’s platform aims to create candidate-ready compounds with unprecedented speed using a combination of deep biology, computational and medicinal chemistry, machine learning, and proprietary big data infrastructure. We are expanding the team of talented scientists who seek to build the future of small molecule drug discovery with creativity and innovation.
Position Summary
We are seeking a Senior Scientist, Pharmacology to provide scientific and technical leadership within our Pharmacology team. This role will design, conduct, and interpret preclinical in vivo and in vitro studies to support lead optimization and progression of pipeline assets toward investigational new drug (IND)-enabling studies. Responsibilities include applying knowledge of G protein-coupled receptor (GPCR) signaling pathways, conducting studies using rodent models to evaluate changes in body weight, body composition, and glycemic control, and documenting study results and recommendations to inform compound selection and development decisions.
Key Responsibilities
Lead the strategy for in vivo pharmacology across obesity and metabolic programs. Translate target biology into robust translational screening cascades and lead optimization workflows.
Design, execute, and oversee complex mouse and rat models (from early discovery to IND-enabling studies). Evaluate pathway-specific biology, receptor internalization kinetics, PD markers, and efficacy readouts to establish clear PK/PD relationships.
Work closely with Biology, Medicinal Chemistry, DMPK, Toxicology, and Translational Science teams to drive candidate selection, nominate development candidates, and support IND filings.
Direct and oversee CRO activities for study design, model development, and execution, ensuring high scientific quality and timely data delivery.
Regularly synthesize and present scientific findings to cross-functional program teams and maintain electronic data management
Minimum Qualifications
Ph.D. in Pharmacology, Physiology, Biology, or a related life sciences discipline, and at least 5+ years of relevant experience.
2+ years of working experience in the biotech or pharmaceutical industry.
Demonstrated ability to independently design and conduct in vivo studies, analyze and interpret results, and communicate findings and recommendations.
Experience performing mouse and rat handling, dosing, blood collection, and tissue collection procedures.
Experience conducting pharmacology studies to support small molecule drug discovery.
Experience coordinating studies with contract research organizations (CROs), including defining study requirements and reviewing deliverables.
Experience using statistical analysis and data visualization tools, such as GraphPad Prism or Excel, and tools for metabolic profiling.
Experience contributing pharmacology data and recommendations to development candidate nomination, coordinating external research partners, and supporting IND-enabling activities.
Preferred Qualifications
Experience analyzing preclinical bone models.
Experience designing, conducting, or interpreting studies involving GPCR pharmacology, regulation of energy balance, or endocrine signaling pathways.
Experience using or interpreting data from diet-induced obesity (DIO), genetic obesity, insulin resistance, or related metabolic disease models.
Experience supporting IND-enabling studies through study planning, data analysis, or preparation of study reports.
Pay Range
$148,757 - $168,800
The annual base salary range listed above represents the lowest and highest amounts we reasonably and in good faith expect to pay for this position at the time of posting. An individual’s starting base salary within this range will be based on relevant experience, job-related skills, and education relevant to the role. In addition to base salary, this position offers bonus and equity opportunities, as well as benefits.
Job details
How this role compares
Computed from every other active Drug Discovery & Preclinical Research role in our database, not just this employer's listings.
We currently track 400 comparable Senior Drug Discovery & Preclinical Research roles across 56 biopharma companies.
Salary context
185 of 400 peers report a salary range (USD, annualized)
Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.
Where these roles are based
Top locations among the 400 comparable roles
+ 14 more countries
Seniority mix
400 of 400 peers have a known seniority level
Therapeutic area mix
38 of 400 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden
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How we calculate "similar"
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Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.
0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.