Amgen Inc. Posted September 4, 2026

Sr. Scientist – Bioinformatics, Computational Biology, Proteomics

South San Francisco, United States Full time
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Amgen Inc. is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Career Category

Scientific

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission, to serve patients living with serious illnesses, drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Sr. Scientist – Bioinformatics, Computational Biology, Proteomics

What You Will Do

Let’s do this. Let’s change the world.

Amgen is seeking a hands-on bioinformatician to develop computational tools and data infrastructure to support the Discovery Proteomics Group. The successful candidate will combine strong scientific expertise in proteomics, bioinformatics, and drug discovery with software engineering skills to understand experimental and discovery needs and translate them into fit-for-purpose computational solutions.  In this vital role, they will conduct statistical analysis, data ingestion, database and tool development, and computational pipeline implementation for proteomics data to support biomarker discovery, target evaluation, experimental design, and mechanism-of-action studies. The successful candidate will join the Discovery Proteomics group at our South San Francisco campus.

Key Responsibilities

This role will enable Amgen’s preclinical pipeline through the delivery of innovative technologies and technical expertise. Responsibilities will include the development and implementation of data analysis, management, and visualization strategies for complex datasets generated by mass spectrometry and other technologies. The successful candidate will be expected to work closely with scientists from different functions and therapeutic areas, deliver and present analysis results to key stakeholders, collaborate across both genomic and proteomic platforms for data integration and mining, and utilize available external resources where appropriate.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Sr. Scientist – Bioinformatics, Computational Biology, Proteomics we seek is a scientifically driven, collaborative, and innovative expert.

Basic Qualifications

Doctorate degree

OR

Master’s degree and 3 years of scientific experience

OR

Bachelor’s degree and 5 years of scientific experience

Preferred Qualifications

PhD in Computational Biology, Bioinformatics, Statistics, Proteomics, or Biology.

Expertise in large-scale quantitative proteomics and other omics data analysis.

Fluency in Python, R, and SQL, and familiarity with analytic techniques/packages necessary for statistical analysis, data processing, data ingestion, data visualization, and basic machine learning approaches. Familiarity with deep learning packages is a plus.

Working knowledge of Unix/Linux and cloud computing (AWS) environments.

Experience in version control, Docker containers, and other best practices for coding project management, reproducible data analysis, and documentation.

Experience in meta-analysis with publicly available large proteomics studies (e.g., GTEx, CPTAC) is a plus. Strong background in biology or chemistry, especially as it pertains to human diseases in the fields of Immunology, Oncology, Inflammation, and Cardiometabolic Disease.

Proven track record of independent critical thinking and scientific achievement.

Strong verbal and written skills, and an ability to work independently as well as in small teams. Willingness and ability to collaborate effectively across different scientific disciplines and with colleagues in cross-functional teams.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

Stock-based long-term incentives

Award-winning time-off plans

Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

Stock-based long-term incentives

Award-winning time-off plans

Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

External/Internal postings:

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Internal only posting (or Pre-ID candidate):

Amgen anticipates accepting applications until 1 week before the posting; however, we may continue accepting applications beyond this date if we do not receive a sufficient number of candidates.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance. Salary Range

146,404.00USD -198,076.00 USD

Job details

Seniority
Senior
Function
Drug Discovery & Preclinical Research
Therapeutic area
Not listed
Location
South San Francisco, United States
Employment type
Full time

How this role compares

Computed from every other active Drug Discovery & Preclinical Research role in our database, not just this employer's listings.

We currently track 206 comparable Senior Drug Discovery & Preclinical Research roles across 38 biopharma companies.

206Comparable roles tracked
198Currently active
38Companies hiring similar roles
12Countries represented

Salary context

85 of 206 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Highest disclosed · Senior Principal Scientist, Pharmacokinetics · Merck $194,100/yr – $305,600/yr
Peer group range $91,450 – $249,850 (median $183,250)

Where these roles are based

Top locations among the 206 comparable roles

United States164
India9
United Kingdom5
Belgium5
Spain4
China's Mainland4

+ 6 more countries

Seniority mix

206 of 206 peers have a known seniority level

Senior103
Principal80
Associate Director23

Therapeutic area mix

21 of 206 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology6
Immunology4
Cardiovascular / CVRM4
Neuroscience3
Respiratory2
Gastroenterology1
Vaccines & Infectious Disease1

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The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

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Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
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Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.