GlaxoSmithKline LLC Posted September 1, 2026

Sr. Director Global RWE and Health Outcomes Oncology

Upper Providence, United States Full time
Health Economics & Outcomes Research Oncology Senior Director
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About this opportunity

Position Summary

As Sr. Director Global RWE and Health Outcomes Oncology, you will be the Data Generation Lead for an oncology asset. You will design and oversee evidence generation plans that support clinical and access decisions across the product lifecycle. You will work closely with Medical Affairs, Clinical Development, Market Access, Commercial, and external partners. We value clear scientific thinking, collaborative leadership, and the ability to translate evidence into practical actions that improve patient care. This role offers growth, visible impact, and alignment with GSK’s mission of uniting science, technology and talent to get ahead of disease together.

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

Work in partnership with the Global Medical Lead to develop the overall data generation plan that aligns clinical, regulatory and access needs across the product lifecycle.

Oversee delivery of non-interventional studies, including protocol development, study execution, analysis and transparent reporting.

Lead and mentor the Data Generation team responsible for real-world evidence including health economic studies and outcomes research for an oncology asset.

Partner with clinical development and medical teams to shape study design, endpoints and comparators to meet payer and HTA expectations.

Represent the team in cross-functional governance and in external scientific dialogue with payers, HTA bodies and academic partners.

Manage resource planning and budget for all evidence activities and track impact of evidence on internal decision-making and external access outcomes.

Why You?

This role is open as either a home based or hybrid position based in the United States. For the hybrid position, you will be expected to spend at least two days per week at the GSK Upper Providence, PA office and the remainder of the time working remotely. We welcome applicants from a range of backgrounds and are committed to inclusion in our team.

Basic Qualifications

We are seeking professionals with the following required skills and qualifications to help us achieve our goals:

Advanced degree (PhD, PharmD, or Master’s) in health outcomes, health economics, epidemiology, biostatistics, clinical research, pharmacy, medicine, or related discipline.

7 + years of experience in health outcomes, real-world evidence, health economics or related functions within the pharmaceutical or healthcare sector.

Hands-on experience with observational study design, comparative effectiveness, economic modeling, or advanced analytical methods.

Experience designing and delivering evidence generation plans to support commercialization, reimbursement, market access or regulatory submissions.

A track record of scientific publications or presentations at major congresses.

Experience leading cross-functional teams and influencing stakeholders across clinical, medical, commercial and access functions.

Strong project management skills with experience managing multiple studies and external partners.

Experience in direct line management.

Excellent written and verbal communication skills with the ability to present complex evidence clearly to diverse audiences.

Preferred Qualifications

If you have the following characteristics, it would be a plus:

Experience leading teams in oncology or another complex therapy area.

Deep knowledge of the US and Global payer and HTA landscape, and familiarity with evidence requirements of major payers and value assessment organizations.

Experience building strategic external collaborations with academic groups, data custodians, or large provider systems.

How to apply

If you are motivated to shape evidence that helps patients access important oncology therapies, we want to hear from you. Please apply and tell us how your experience aligns with the responsibilities and qualifications above. We look forward to learning how you can contribute to our team and to GSK’s mission.

#LI-GSK

Skills

Cross-Functional Leadership, Digital Fluency, Enterprise Thinking, Evidence Based Decision Making, Flexible Mindset, High Impact Communication, Launch Excellence, Patient Journey

The US annual base salary for new hires in this position ranges from $226,500 to $377,500. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.

Please visit  GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at -  usrecruitment.adjustments@gsk.com

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Job details

Seniority
Senior Director
Function
Health Economics & Outcomes Research
Therapeutic area
Oncology
Location
Upper Providence, United States
Employment type
Full time

How this role compares

Computed from every other active Health Economics & Outcomes Research role in our database, not just this employer's listings.

We currently track 6 comparable Senior Director Health Economics & Outcomes Research roles across 3 biopharma companies.

6Comparable roles tracked
4Currently active
3Companies hiring similar roles
3Countries represented

Salary context

1 of 6 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Only peer reporting · Director, Patient Centered Science, Late CVRM · AstraZeneca $194,147/yr – $291,220/yr
Peer group range $242,684 – $242,684 (median $242,684)

Where these roles are based

Top locations among the 6 comparable roles

United States4
Spain1
Japan1

Seniority mix

6 of 6 peers have a known seniority level

Director5
Senior Director1

Therapeutic area mix

4 of 6 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Cardiovascular / CVRM1
Vaccines & Infectious Disease1
Respiratory1
Oncology1

Currently open similar roles

This posting is closed, but here are live openings closest to it -- ranked by similarity, not by how well you'd qualify for them.

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Same function Same seniority Same country
50%similar
AstraZeneca Boston, Massachusetts, United States of America Director
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35%similar
GlaxoSmithKline K.K. Akasaka, Japan Director
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35%similar
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Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Senior Director, Global Real-World Evidence & Health Outcomes Research Lead, Specialty Medicines
GlaxoSmithKline LLC · Philadelphia, United States · Senior Director
Function Therapeutic area Seniority Country
50%
Director, Patient Centered Science, Late CVRM
AstraZeneca · Boston, Massachusetts, United States of America · Director
Function Therapeutic area Adjacent seniority Country
35%
Vaccine Director, Japan Real-World Evidence & Health Outcomes Research
GlaxoSmithKline K.K. · Akasaka, Japan · Director
Function Therapeutic area Adjacent seniority Country
35%
HTA & Modelling Science Director
AstraZeneca · Barcelona, Spain · Director
Function Therapeutic area Adjacent seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.