Senior Scientist, Process Safety, Drug Substance New Chemical Entity (Ridgefield, CT, United States, Connecticut)
About this opportunity
Description
As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development, and delivery of our products to our patients and customers. Our global presence provides an opportunity for all employees to collaborate internationally, offering visibility and the opportunity to directly contribute to the company's success. We realize that our strength and competitive advantage lie with our people. We support our employees in several ways to foster a healthy working environment, meaningful work, mobility, networking, and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.
The Senior Scientist, Process Safety, Drug Substance New Chemical Entity (NCE) is responsible for evaluating, characterizing, and mitigating thermal and reactive hazards associated with pharmaceutical compounds, intermediates, chemical processes, and active pharmaceutical ingredient (API) manufacturing operations. The incumbent will support safe process development, scale-up, and technology transfer through thermal analysis, reaction calorimetry, process safety assessments, and hazard risk management. In addition, this role will collaborate with process research, development, scale-up, Technical Services and Environmental Health & Safety (EHS).
Duties & Responsibilities
Thermal Hazard Assessment Design and execute thermal stability studies for APIs, intermediates, and reaction mixtures.
Assess decomposition behavior, self-heating potential, runaway reaction risks, and energetic hazards.
Evaluate safe operating limits for chemical processes and unit operations.
Establish thermal safety parameters for scale-up and manufacturing operations.
Thermal Analysis & Calorimetry Conduct thermal characterization using: Differential Scanning Calorimetry (DSC)
Thermogravimetric Analysis (TGA)
Accelerating Rate Calorimetry (ARC)
Reaction Calorimetry (RC1 or equivalent)
Interpret calorimetric and kinetic data to determine process safety risks.
Process Safety Evaluation Perform process hazard assessments for R&D manufacturing processes.
Conduct thermal risk assessments and reaction hazard reviews
Identify potential runaway reaction scenarios and recommend mitigation strategies.
Process research and Development Support Partner with process chemists during route scouting, optimization, and scale-up activities.
Define critical process safety parameters, including: Maximum Technical Temperature (MTT)
Maximum Temperature of Synthesis Reaction (MTSR)
Time to Maximum Rate (TMR)
Safe temperature operating windows
Support kilo lab and pilot plant campaigns.
Data Analysis & Reporting Prepare comprehensive thermal hazard reports and technical recommendations Present findings to interdisciplinary project teams and leadership.
Maintain detailed experimental documentation in compliance with company standards.
Develop process safety databases and internal best practices.
Compensation Data
The base salary range for this position is $140,800.00 to $211,200.00 USD. The position may be eligible for a role-specific discretionary bonus, relocation assistance, and/or other compensation elements. We continuously review market data and may adjust salary ranges as needed in the future. Actual compensation will be based on job-related factors such as skills, experience, qualifications, and other factors permitted by law. Benefits include medical, dental, and vision coverage, retirement savings opportunities, paid time off, paid holidays, disability and life insurance benefits, and other company-sponsored benefits. For additional information regarding our benefits and Total Rewards offerings, please click here .
Requirements
Ph.D. in Chemistry (preferred Organic Chemistry), Chemical Engineering, Pharmaceutical Sciences, Process Safety Engineering, or related field with at least three (3) years of experience.
OR M.S. with at least six (6) years
OR B.S. with at least eight (8) years of relevant experience.
DSC, TGA, ARC, Reaction Calorimetry
Thermal Decomposition Kinetics
Risk assessment
Scale-up principles and technical reporting
Cross-functional collaboration.
Eligibility Requirements:
Must be legally authorized to work in the United States without restriction.
Must be willing to take a drug test and post-offer physical (if required).
Must be 18 years of age or older.
Desired Skills, Experience and Abilities
Pharmaceutical R&D
API Development
Chemical Development and Scale-Up
Contract Development and Manufacturing Organizations (CDMOs)
Specialty Chemicals
Knowledge of: Pharmaceutical API manufacturing
High-energy chemistry
Crystallization and drying safety
Dust explosion assessment
Computational modeling and kinetics software
Job details
How this role compares
Computed from every other active Manufacturing & CMC role in our database, not just this employer's listings.
We currently track 641 comparable Senior Manufacturing & CMC roles across 87 biopharma companies.
Salary context
229 of 641 peers report a salary range (USD, annualized)
Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.
Where these roles are based
Top locations among the 641 comparable roles
+ 23 more countries
Seniority mix
641 of 641 peers have a known seniority level
Therapeutic area mix
2 of 641 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden
Similar opportunities
The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.
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How we calculate "similar"
No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.
Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.
0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.