AstraZeneca Posted September 15, 2026

Senior Scientist - Laboratory Automation – Process Chemistry / Analytical

Macclesfield, United Kingdom Full time
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AstraZeneca is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Join our expert team at AstraZeneca to pioneer a new future to meet global healthcare challenges. Be part of shaping a better future for all, supporting healthy communities by addressing the global societal and economic burden of disease. We are committed to leading in sustainability. Backed by a belief in the connection between the health of our business, people and the planet.

In Chemical Development we believe that nothing is impossible, and we are determined to push the boundaries of science to deliver medicines to our patients. We combine people’s technical knowledge and understanding with their talent and drive to design, develop and optimise synthetic routes and processes that deliver the active pharmaceutical ingredients of our medicines in a sustainable, commercially viable way. We believe in innovation and continuous improvement, working closely with colleagues in academia and across industry, to ensure that we apply the cutting-edge technologies and principles in the processes we develop.

We have an exciting opportunity for a Senior Scientist to join the Automation & Data Science unit as a Laboratory Automation Scientist. The role will develop, deliver and support new automation platforms, while maintaining our growing fleet of automated and semi-automated experimental equipment.  This role is key to advance our Lab of the Future programme by enabling effective data generation and seamless data flows across the digital laboratory ecosystem.

As part of a team of automation specialists, you will take ownership of a diverse range of laboratory instruments, ensuring their availability, performance and suitability for experimental workflows. You will troubleshoot and optimise existing systems while developing and deploying new automated workflows for wider departmental use.

You will support the day-to-day activities of the laboratory facilities management team, ensuring that troubleshooting and routine laboratory housekeeping are completed effectively and in line with departmental requirements.

In your role you will identify and compare existing capabilities, develop or configure prototypes, and pilot the preferred approach with selected teams.  Following a successful pilot, the role holder will support the handover to the chemistry/analytical teams.

As a key and central part of the Lab of the Future program, you will work in close partnership with chemists, engineers, data scientists, and IT, enabling data-rich experimentation and smart process development. Your role encompasses hands-on interaction with automation hardware/software, programming and troubleshooting systems, collaborating on integration projects, and ensuring solutions are robust and compliant with quality requirements.

Key Responsibilities: 

Drive the design, implementation, and integration of automated platforms for synthetic and analytical chemistry, ensuring efficiency from reagent management to data capture and modelling.

Translating analytical workflows into practical, user-centred automation solutions, supporting a wide range of technical areas from sample preparation to various analytical techniques, such as chromatography and spectroscopies/spectrometries.

Program and operate laboratory robotics, troubleshoot and resolve technical issues, and work closely with vendors and internal teams to optimize system performance.

Lead or support technology evaluation, platform upgrades, and new automation initiatives that advance laboratory digital maturity.

Train and empower laboratory scientists on use, maintenance, and best practice for new and existing automation systems.

Ensure compliance with laboratory and IT quality standards, including software validation, change management, and system security and safety protocols.

Ensure safe laboratory operations and prepare the required safety documentation.

Streamline laboratory operations through the implementation of lab governance activities such as lab mapping, automated inventory tracking and QR-enabled service-request management.

Execute practical experimental work on our automated platforms. This includes the execution of instrument testing protocols when designing new workflows or assuring data quality on new instrument investments. It may extend to provision of project data which feeds the development activities delivering new drug substance targets.

Provide expert hands-on support to the facilities management team delivering the MettlerToledo fleet maintenance.

Essential requirements 

A degree (at PhD or lower-level with equivalent professional experience) in chemistry, chemical robotics or mechanical engineering, or a related technical field with hands-on experience in laboratory or process automation.

Proficiency in programming and scripting for automation platforms, robotics, and laboratory informatics.

Experience with CAD and prototyping new tools and equipment

Operational experience with laboratory automation systems, including design/development, troubleshooting, and optimization of robotic platforms.

Proven record of innovation through, for instance, authorship of papers, inventor status on patents, or presenting at external conferences.

The ability to develop and analyse multiple solutions to problems.

​

Desirable requirements 

Synthetic organic chemistry laboratory experience and/or experience working in analytical laboratories and experience of chromatography or spectroscopic characterisation techniques e.g. UHPLC, NMR, MS

Experience within a process or manufacturing environment

Experience from working with automated analytical procedures

Experience of the analytical area such as method development and method validation.

Familiarity with data science methodologies and AI/ML implementations in laboratory automation.

Knowledge of GLS requirements for instrument maintenance

Experience working with ALRs and HTE automated platforms

Skills and capabilities 

Ability to challenge, innovate, think critically and flexibly, bringing new solutions and opportunities for chemical development.

Excellent communication skills, with the ability to communicate across interfaces of scientific disciplines, culture, and expertise both internally and externally.

The ability to confidently participate in, and potentially lead, improvement projects.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Why AstraZeneca:Here, your science moves with purpose. You will work with cutting-edge biotechnology, new drug modalities, and rich data to shape how serious diseases are treated, including opportunities at the earliest stages where impact is greatest. We bring diverse experts together to spark bold ideas, apply innovative methods like AI and novel selection strategies, and learn quickly from real evidence. We value kindness alongside ambition, empowering you to take smart risks, collaborate deeply, and see your discoveries turn into medicines that reach patients.

Call to Action:If you are ready to elevate peptide discovery and build therapies that matter, step into this role and shape what comes next.

Date Posted

23-set.-2026

Closing Date

07-out.-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

Job details

Seniority
Senior
Function
Manufacturing & CMC
Therapeutic area
Not listed
Location
Macclesfield, United Kingdom
Employment type
Full time

How this role compares

Computed from every other active Manufacturing & CMC role in our database, not just this employer's listings.

We currently track 494 comparable Senior Manufacturing & CMC roles across 78 biopharma companies.

494Comparable roles tracked
440Currently active
78Companies hiring similar roles
32Countries represented

Salary context

204 of 494 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Lowest disclosed · Associate Director, Digital Scientific Workflows · Merck $0/hr – $0/hr (≈ $0–$0/yr)
Highest disclosed · Senior Principal Scientist, Upstream Process Development Group Lead · Merck $190,800/yr – $300,300/yr
Peer group range $0 – $245,550 (median $150,600)

Where these roles are based

Top locations among the 494 comparable roles

United States325
India38
Netherlands19
Ireland16
United Kingdom10
Singapore9

+ 26 more countries

Seniority mix

494 of 494 peers have a known seniority level

Senior327
Principal88
Associate Director79

Therapeutic area mix

1 of 494 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Dermatology & Aesthetics1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
Moderna Biotech Manufacturing UK Ltd Oxford, United Kingdom Senior
Same function Same seniority Same country
60%similar
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Same function Same seniority Same country
60%similar
Ipsen Biopharm Ltd Wrexham, United Kingdom Senior
Same function Same seniority Same country
60%similar
Aventis Pharma Limited Reading, United Kingdom Senior
Same function Same seniority Same country
60%similar
Novo Nordisk Oxford, United Kingdom Senior
Same function Same seniority Same country
60%similar
Roche Welwyn, Hertfordshire, United Kingdom Senior
Same function Same seniority Same country

Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
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Function Therapeutic area Seniority Country
60%
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50%
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Function Therapeutic area Adjacent seniority Country
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Associate Director, CMC Regulatory Science, International
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Function Therapeutic area Adjacent seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.