Senior Pharmacokineticist, Translational Pharmacokinetics/Pharmacodynamics

Build Our Future Together

We are looking for a Senior Pharmacokineticist that will support Pharmacokinetics and Translational Pharmacokinetics/Pharmacodynamics requirements for Discovery and ND-stage project teams. Efforts include providing input/oversight and direction to early preclinical/nonclinical in vivo studies, interfacing with Therapeutic Focus Area scientific staff performing the preclinical studies and directing/managing non-clinical Pharmacokinetics studies. Preparing and presenting the analyses to internal project teams and senior management, and writing summary reports and documents to support regulatory filings.

When & where:

Work Location: Tarrytown, NY

Work model/flexibility: 4 days per week onsite

Discover your role:

Serve on Discovery-stage project teams as a subject matter authority for Translational Pharmacokinetics / Pharmacodynamics, providing input regarding the design of discovery and preclinical PK and/or pharmacology studies.

Collaborate optimally with various groups within Regeneron, including Therapeutic Proteins, Therapeutic Function Areas, Assay Development group, Precision Medicine, Preclinical Operations, Toxicology and TPK/PD management to develop a PK strategy for each project and then delivering the required output.

Effectively communicate project team queries, requests and expectations (i.e. timing and results) from the Project Teams to management.

Conduct and report PK and PKUPD analyses using data derived from preclinical (nonclinical) studies.

Work in close association with the Toxicology, Pathology, Clinical Pharmacology, Quantitative Pharmacology (modeling & simulation) and the Translational Modeling groups within the Drug Safety and Pharmacometrics Department, to deliver the required data and study reports / regulatory documents to support project progression.

Maintain an up-to-date knowledge of the relevant scientific literature as well as regulatory guidance and best practices as they pertain to TPK/PD.

This role requires:

PhD in Pharmacology, Pharmacokinetics, Biology/Molecular Biology, or Biochemistry with more than 5+ years of relevant experience in biotech or pharma.

Theoretical and applied understanding of PK and PD to interpret the pharmacology and biology of therapeutic proteins. Experience with other modalities such as siRNA, CRISPR-based therapeutics, and cell therapies is highly beneficial.

Proven ability to plan, coordinate, lead PK and/or PK/PD studies, and analyze related data.

Familiarity with PK/PD (e.g., WinNonLin), data visualization and AI software and experience writing scientific reports and regulatory summaries.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all  qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate.  The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits.  Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/ . For other locations, additional information will be provided during the recruitment process.  If you have any questions, please speak with your recruiter.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)

$128,600.00 - $210,000.00