Senior Manager, Responsible AI Governance

Career Category

Information Systems

Job Description

Join our team at AMGEN Capability Center Portugal, consistently recognized among the top companies in the Best Workplaces™ ranking by Great Place to Work® in Portugal. In 2026, we were once again distinguished as one of the top Best Workplaces in the country (category 201–500 employees), reinforcing our commitment to an exceptional employee experience and workplace culture.

We are a team of over 500 talented individuals, spanning more than 30 functions and areas of expertise, and representing over 40 nationalities. Together, we bring diverse perspectives and professional backgrounds to help shape the future of healthcare through innovation and technology.

This is your opportunity to explore a world of possibilities across areas such as Data & Analytics, Digital, Technology & Innovation, Cybersecurity, R&D Operations, Global Distribution, Finance, Regulatory Affairs, General & Administrative, Human Resources, and many more.

Located in the heart of Lisbon, our AMGEN office fosters a culture of innovation, excellence, and purpose. Come thrive with us at AMGEN, supporting our mission To Serve Patients.

What we do at AMGEN matters in people’s lives.

SENIOR MANAGER, RESPONSIBLE AI GOVERNANCE

At A MGEN ,   T echnology   isn’t   just a support   function, it’s   a catalyst for discovery, transformation, and real-world impact. Here, your ideas fuel innovation that improves and saves lives   of patients in dire need of our medicines . Are you ready to do meaningful work that matters?

Live

What will you do

AI is creating new opportunities to accelerate scientific discovery, strengthen decision-making, and ultimately help deliver better outcomes for patients. Realizing that potential responsibly requires governance that is not only principled, but practical, scalable, and embedded in how AI is developed and used across the enterprise.

The Senior Manager, Responsible AI Governance sits within Amgen’s Responsible AI team in the Artificial Intelligence & Data Science organization. This senior individual-contributor role helps shape and mature Amgen’s enterprise Responsible AI governance framework and operating model.

The role connects external expectations to practical internal implementation. Working across Legal, Regulatory Policy, Quality, Privacy, Cybersecurity, Technology, Research, and business functions, you will translate emerging AI regulations, guidance, standards, and other requirements into scalable governance standards and processes.

You will also serve as a senior Responsible AI governance subject-matter expert and trusted partner in in audits, inspections, internal reviews, and other assurance-related engagements engagements.

The responsibilities of the role will include:

Shape the evolution of Amgen’s Responsible AI governance framework and operating model by defining and advancing governance controls, processes, and evidence practices for AI models and systems.

Assess emerging AI regulations, regulatory guidance and standards, and assurance themes; determine their implications for Amgen and translate them into clear recommendations for governance strategy, requirements, controls, and operating processes.

Support audits, inspections, internal reviews, and regulatory information requests led by accountable functions by articulating Amgen’s enterprise AI governance approach and coordinating relevant evidence.

Develop clear governance narratives, executive materials, and decision-support content that frame key Responsible AI issues, options, risks, and recommendations for senior leaders and governance forums.

Advance the maturity of Amgen’s enterprise Responsible AI governance operating model, including roles and accountabilities, escalation pathways, governance forums, reporting, and evidence expectations.

Act as a key execution lead for the Responsible AI governance program, leading high-priority initiatives and coordinating cross-functional delivery.

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The tech professional we   seek   is a creative problem-solver and a team player with these qualifications:

Minimum requirements

Degree educated and 7 years of experience in Responsible AI, AI governance, AI risk, technology policy, regulatory policy, quality systems, compliance, audit/inspection readiness, AI/ML, or a related discipline.

Demonstrated expertise translating external regulatory, policy, audit, inspection, or standards-based expectations into practical governance requirements, controls, procedures, or operating models.

Strong understanding of Responsible AI governance, AI risk management, and emerging AI regulatory and policy frameworks, including the NIST AI Risk Management Framework and Trustworthy AI characteristics, EU AI Act concepts, and relevant FDA and international regulatory guidance.

Ability to build clear, evidence-based governance narratives and influence senior stakeholders across governance, control, technology, and business functions in a complex matrixed environment.

Technical fluency sufficient to engage credibly with AI/ML, data science, engineering, and product teams on model and system lifecycle, monitoring, documentation, controls, and deployment considerations.

Fluency in English.

Preferred requirements

Experience in biotechnology, pharmaceuticals, healthcare, financial services, or another highly regulated industry, including familiarity with FDA, EMA, GxP, quality-system, audit, or inspection environments.

Experience supporting regulatory inspections, internal or external audits, quality-system activities, or audit-response programs.

Experience in technology policy, AI ethics, digital ethics, or responsible innovation, including translating ethical principles into practical governance requirements or operating practices.

Experience developing model risk management, third-party AI, AI lifecycle, or enterprise technology governance standards.

Strong analytical, organizational, and problem-solving skills with high attention to detail.

Excellent communication and stakeholder management skills, with the ability to work effectively across functions and seniority levels.

Team-oriented with a high degree of initiative and self-motivation.

Thrive

What you can expect   of   us

As we work to develop treatments that take care of others, we also care deeply for our teammates’ well-being and growth.

Work That Matters   – Build tech that accelerates scientific breakthroughs and helps patients worldwide.

Modern Tech Stack   – Cloud-first, automation-focused, AI-powered.

Global Scale, Agile Mindset   – Collaborate across continents while working in nimble, high-impact teams.

Continuous Learning   – Access to certifications,   trainings , mentorship, and career mobility.

A MGEN   Total Rewards Plan   – Comprehensive benefits in healthcare, finance, and well-being.

Flexibility   – Hybrid work model with time split between our Lisbon office and remote work.

APPLY NOW

Objects in your future are closer than they appear. Join us.

CAREERS.AMGEN.COM

EQUAL OPPORTUNITY STATEMENT

AMGEN is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided   a reasonable   accommodation to   participate   in the job application or interview process, to perform crucial job functions, and to receive other benefits and privileges of employment. Please contact us to request   an accommodation .

. Salary Range

EUR -  EUR