Senior Manager Manufacturing – Night Shift Operations Performance & Integration
About this opportunity
Career Category
Manufacturing
Job Description
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission, to serve patients living with serious illnesses, drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity-related conditions, rare diseases, inflammatory conditions and cancer. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Night Senior Manager Manufacturing – Night Operations Performance & Integration (Continuous Improvement)
What you will do
Let’s do this. Let’s change the world. In this vital role the Night Shift Senior Manager of Manufacturing at Amgen is responsible for establishing and sustaining a strong night-shift operating system that provides off-shift operational direction for Commercial Operations and for Project based Commissioning and Qualification (C&Q) coverage, ensuring the right cross-functional resources are engaged, issues are escalated and resolved with urgency, and manufacturing performance is actively managed across the shift.
Partners with Engineering, Automation, QA, Technology, Maintenance, Supply Chain/Warehouse, Capital Projects.
Responsibilities
Serve as the senior Manufacturing integration point across night-shift operations during significant operational events.
Establish and sustain the night-shift Tier structure, operating cadence, escalation model, and performance-management routines.
Coordinate Manufacturing, Quality Assurance, Engineering, Automation, Maintenance, Supply Chain/Warehouse, and other site resources required to maintain safe, compliant, and reliable operations.
Drive escalation of significant resource constraints, technical barriers, competing priorities, or unresolved operational issues to appropriate site or functional leadership.
Monitor overall night-shift Manufacturing performance across production lines, including downtime, OEE, schedule attainment, recurring interruptions, escalation effectiveness, and chronic losses.
Partner with the daytime Manufacturing Senior Manager, Continuous Improvement Senior Manager and MFG process Support Senior Manager to identify, prioritize, and execute improvement opportunities across off-shift, including 5S, visual management, standard work, workplace organization, waste reduction, flow improvement, and training operating discipline.
Provide coaching and situational leadership to Front Line Managers during complex operational events
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The professional we seek will possess these qualifications.
Basic Qualifications:
Doctorate degree and 2 years in GMP manufacturing, process development, or combination device, and/or manufacturing focused six sigma lean operational excellence.
OR
Master’s degree and 6 years in GMP manufacturing, process development, or combination device, and/or manufacturing focused six sigma lean operational excellence.
OR
Bachelor’s degree and 8 years in GMP manufacturing, process development, or combination device, and/or manufacturing focused six sigma lean operational excellence.
OR
Associate’s degree and 10 years in GMP manufacturing, process development, or combination device, and/or manufacturing focused six sigma lean operational excellence.
OR
High school diploma / GED and 12 years in GMP manufacturing, process development, or combination device, and/or manufacturing focused six sigma lean operational excellence.
In addition to meeting at least one of the above requirements, you must have a minimum of 2 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced above
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental & vision coverage, and life & disability insurance
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.
Apply now and make a lasting impact with the Amgen team.
careers.amgen.com
In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.
Sponsorship
Sponsorship for this role is not guaranteed.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer. We make all employment decisions without regard to race, color, religion, sex or any other characteristic protected by applicable law.
We provide reasonable accommodations to applicants and employees with disabilities, consistent with legal requirements. Please contact us to request accommodation.
. Salary Range
136,227.80USD -184,308.20 USD
Job details
How this role compares
Computed from every other active Manufacturing & CMC role in our database, not just this employer's listings.
We currently track 661 comparable Manager Manufacturing & CMC roles across 88 biopharma companies.
Salary context
205 of 661 peers report a salary range (USD, annualized)
Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.
Where these roles are based
Top locations among the 661 comparable roles
+ 35 more countries
Seniority mix
661 of 661 peers have a known seniority level
Therapeutic area mix
9 of 661 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden
Similar opportunities
The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.
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How we calculate "similar"
No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.
Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.
0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.