AstraZeneca Posted August 12, 2026

Senior Maintenance Technician

Tarzana, California, United States of America Full time
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AstraZeneca is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

There are 2 positions available, 1 for first and 1 for 2nd shifts:1) First shifts are 5am-1:30pm and 7am-3:30pm2) Second Shifts are 1pm-9:30pm and 2pm-10:30pmYou’ll lead maintenance execution, troubleshoot complex utilities and equipment, and mentor teammates, all while partnering closely with Manufacturing, Quality, and Engineering.

What you’ll do:​Preventive/predictive/corrective maintenance on cleanroom HVAC, BMS/EMS, process equipment (incubators, biosafety cabinets, centrifuges, freezers, pumps, single‑use systems), and critical utilities (clean steam, chilled water, gases, compressed air). Operate and troubleshoot boilers, steam generators, cooling towers/chillers, and water treatment systems. Support cleanroom integrity (HEPA, pressure differentials, temp/RH), lead root cause analysis and CAPA, calibrate instruments, and contribute to equipment qualification (URS/IQ/OQ/PQ). Own documentation in CMMS with impeccable GDP, and champion EHS (LOTO, permits, OSHA/NFPA 70E).

What you’ll bring:

Experience: 6–10+ years in GMP biopharma or cell therapy/ATMP maintenance, including cleanrooms and regulated utilities.

Education: High School Diploma/GED, associate degree or technical diploma in Mechanical/Electrical/Mechatronics/Industrial Maintenance or equivalent military/apprenticeship training; or related field a plus.

Technical expertise: HVAC for controlled environments, clean steam/chilled water/process gases, electrical systems up to site-authorized voltage, reading P&IDs/schematics/single-line diagrams, basic PLC/HMI.

GMP savvy: cGMP, GDP, deviations/CAPA, validation/qualification for utilities.

Systems: CMMS, BMS/EMS; comfortable with digital workflows and e-logbooks.

Soft skills: Clear communication, teamwork, prioritization, and mentoring.

Nice to have: Vibration/thermography basics, manufacturer training on chillers/controls, GxP/cleanroom coursework, safety certifications.

Work environment: Cleanrooms and mechanical spaces; lift up to 50 lbs, climb ladders, work at heights, wear PPE, and support an on-call rotation.

Why this role matters: Your expertise keeps our therapeutics on track, maintaining validated systems, driving reliability, and enabling patients to receive life-changing treatments.

Ready to make an impact? Apply now and help us advance cell therapy with safe, reliable, and compliant operations.

The annual base pay (or hourly rate of compensation) for this position ranges from $ 71,749.60 - 107,624.40 . Our positions offer eligibility for various incentives, an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted

09-Nov-2026

Closing Date

26-Nov-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

Job details

Seniority
Senior
Function
Manufacturing & CMC
Therapeutic area
Not listed
Location
Tarzana, California, United States of America
Employment type
Full time

How this role compares

Computed from every other active Manufacturing & CMC role in our database, not just this employer's listings.

We currently track 632 comparable Senior Manufacturing & CMC roles across 86 biopharma companies.

632Comparable roles tracked
584Currently active
86Companies hiring similar roles
30Countries represented

Salary context

227 of 632 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Lowest disclosed · Senior Technician Calibration - Maintenance · Mylan Technologies, Inc. $37,000/yr – $80,000/yr
Highest disclosed · Associate Director / Director - Biologics Drug Product Development · AbbVie $160,500/yr – $305,000/yr
Peer group range $58,500 – $232,750 (median $151,700)

Where these roles are based

Top locations among the 632 comparable roles

United States418
India44
Ireland25
Netherlands19
China12
Switzerland11

+ 24 more countries

Seniority mix

632 of 632 peers have a known seniority level

Senior402
Principal126
Associate Director104

Therapeutic area mix

2 of 632 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Dermatology & Aesthetics1
Vaccines & Infectious Disease1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
AbbVie North Chicago, IL Senior
Same function Same seniority Same country
60%similar
AbbVie North Chicago, IL Senior
Same function Same seniority Same country
60%similar
AbbVie North Chicago, IL Senior
Same function Same seniority Same country
60%similar
AbbVie North Chicago, IL Senior
Same function Same seniority Same country
60%similar
Novartis East Hanover, United States Senior
Same function Same seniority Same country
60%similar
Pfizer Andover, United States Senior
Same function Same seniority Same country

Notify me about similar jobs

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How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
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Function Therapeutic area Seniority Country
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Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.