Vertex US Distribution Posted September 8, 2026

Senior Director, US Market Access Strategy, Povetacicept (POVE)

Boston, United States Full time
Market Access Senior Director
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Vertex US Distribution is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Job Description

Vertex Pharmaceuticals operates at the forefront of scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF), sickle cell disease, beta-thalassemia, and moderate to severe acute pain. Vertex also has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases, including programs in kidney diseases and Type 1 diabetes.

Vertex is seeking an experienced Senior Director, US Market Access Strategy to lead market access initiatives for povetacicept (POVE) in IgA Nephropathy (IgAN) and future indications. This individual will guide the team responsible for developing and executing payer marketing, pricing, contracting, and evidence strategies that support POVE patient access while preparing for future label expansion opportunities. The role requires a leader who understands the complexities of specialty product commercialization and the evolving evidence expectations of US payers.

Key Duties and Responsibilities:

Lead POVE pricing and contracting strategies across current and future indications

Oversee development of the POVE value proposition in partnership with HEOR

Spearhead the Market Access launch readiness teams to ensure all US Market Access functional areas are aligned to strategy and all tactical elements are finalized in preparation for FDA approval

Identify and address key product barriers to access and performance by applying advanced understanding of contracting and pricing strategies, payer analytics, and payer market trends

Develop brand and market access strategies by payer channel to support patient access for POVE through the creation and delivery of impactful market access resources

Implement a player-coach leadership style to achieve key access objectives while overseeing a team of 3-4 direct reports

Lead the annual long-range planning (LRP) process and US Market Access brand planning for POVE in IgAN and future indications

Develop, train, and implement the necessary promotional resources and reimbursement pull-through that support field account teams’ efforts with key customers

Secure and oversee external vendors to deliver resources and strategic insights on time and within budget

Develop key performance indicators (KPIs) and metrics to assess impact of key initiatives

Function as a trusted subject matter expert to internal colleagues and external customers

Knowledge and Skills:

Deep experience in product commercialization and access strategy for launch products across benefits

Previous contract strategy leadership experience in the pharmaceutical/biotech or healthcare industry

Experience developing and articulating compelling payer value propositions

Proven track record of meeting or exceeding access objectives and goals, both as an individual and as part of a team

Expert knowledge of US healthcare system, including gov’t and commercial payers, policy, and regulatory environment

Pharmacy and medical benefit experience

Strong understanding of specialty pharmacy and distribution strategy

Excellent communication skills with experience presenting to customers and internal leadership

Demonstrated ability to successfully lead cross-functional teams, influence without direct authority, foster collaboration, and succeed in a highly matrixed environment

Ability to perform in a fast-paced environment, manage multiple priorities simultaneously, and work effectively across cross-functional teams

Preference for candidate with prior direct disease area experience

Experience leading and managing a team

Education and Experience:

Bachelor’s degree in relevant field (advanced degree preferred)

Typically requires 12 years of experience or the equivalent combination of education and experience

Typically requires 5 years of supervisory experience

Launch experience required

Payer contracting experience preferred

Location: HQ (Boston –Seaport) on a hybrid schedule (3 days a week); relocation available

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

$232,000 - $348,000

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:

1.    Hybrid: work remotely up to two days per week; or select

2.    On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Job details

Seniority
Senior Director
Function
Market Access
Therapeutic area
Not listed
Location
Boston, United States
Employment type
Full time

How this role compares

Computed from every other active Market Access role in our database, not just this employer's listings.

We currently track 55 comparable Senior Director Market Access roles across 21 biopharma companies.

55Comparable roles tracked
51Currently active
21Companies hiring similar roles
9Countries represented

Salary context

19 of 55 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $232,000/yr – $348,000/yr
Lowest disclosed · Regional Account Director for IA and IL · Genzyme Corporation $172,500/yr – $249,167/yr
Highest disclosed · Vice President, US Market Access Lead - Specialty Care · Pfizer $300,100/yr – $500,100/yr
Peer group range $210,833 – $400,100 (median $252,083)

Where these roles are based

Top locations among the 55 comparable roles

United States44
Switzerland3
Japan2
United Kingdom1
Belgium1
Dubai1

+ 3 more countries

Seniority mix

55 of 55 peers have a known seniority level

Director39
Senior Director10
Executive/VP6

Therapeutic area mix

22 of 55 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Neuroscience7
Oncology6
Immunology4
Rare Disease3
Cardiovascular / CVRM1
Dermatology & Aesthetics1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
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AstraZeneca Boston, Massachusetts, United States of America Senior Director
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60%similar
Pfizer New York City, United States Senior Director
Same function Same seniority Same country
60%similar
Genzyme Corporation Cambridge, United States Senior Director
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60%similar
Otsuka America Pharmaceutical, Inc Remote, United States Senior Director
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60%similar
Genzyme Corporation Morristown, United States Senior Director
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Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
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Function Therapeutic area Seniority Country
60%
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Function Therapeutic area Seniority Country
60%
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CSL Behring L.L.C. · King of Prussia, United States · Senior Director
Function Therapeutic area Seniority Country
60%
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AstraZeneca · Wilmington, Delaware, United States of America · Senior Director
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.