Lilly Posted September 18, 2026

Senior Director Toxicology

Indianapolis, Indiana, United States of America FULL_TIME
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Lilly is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work, but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

We are seeking a Senior Director of Toxicology to provide scientific and administrative leadership. Responsibilities include allocating and prioritizing resources, consulting on scientific and business issues, budgeting and approval of expenses, communicating and implementing corporate priorities and policies, implementing departmental or divisional strategy, streamlining business practices and service on intra- and inter-departmental committees. This role plays an integral part in developing world-class medicines for Lilly.

We offer mentorship and career development opportunities in a dynamic and diverse environment. Do your skills match our needs? Apply today and join the Lilly family!

Responsibilities

Provide strategy planning and oversight of toxicology research and portfolio support activities of the division

Review and approve Regulatory submissions

Supervise research and professional staff. Develop performance plans and objectives for staff, conduct performance reviews, and provide mentoring and coaching to staff to facilitate their professional development.

Serve on toxicology leadership and scientific review committees, providing strategic oversight and approval of toxicology study designs and results

Engage in external partnerships and manage business relationships and vendors

Perform responsibilities delegated by senior management

Basic Qualifications

PhD in Toxicology, or related science OR

DVM with MS in Toxicology, public health or related science

10+ Technical Expertise in Pharmaceutical Toxicology

10+ Regulatory Experience with nonclinical safety issues

Additional Skills/Preferences

DABT preferred but not required

Familiarity with ICH and Regional Regulatory guidance

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

$163,500 - $239,800

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

#WeAreLilly

Job details

Seniority
Senior Director
Function
Drug Discovery & Preclinical Research
Therapeutic area
Not listed
Location
Indianapolis, Indiana, United States of America
Employment type
FULL_TIME

How this role compares

Computed from every other active Drug Discovery & Preclinical Research role in our database, not just this employer's listings.

We currently track 68 comparable Senior Director Drug Discovery & Preclinical Research roles across 26 biopharma companies.

68Comparable roles tracked
64Currently active
26Companies hiring similar roles
6Countries represented

Salary context

38 of 68 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $163,500/yr – $239,800/yr
Highest disclosed · Executive Director, Biotherapeutics DMPK · Vertex Pharmaceuticals Inc (US) $268,000/yr – $402,000/yr
Peer group range $0 – $335,000 (median $252,900)

Where these roles are based

Top locations among the 68 comparable roles

United States59
India2
China2
United Kingdom2
Portugal1
Spain1

Seniority mix

68 of 68 peers have a known seniority level

Director43
Senior Director15
Executive/VP10

Therapeutic area mix

15 of 68 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology10
Neuroscience2
Vaccines & Infectious Disease1
Immunology1
Respiratory1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
Gilead Sciences, Inc. Foster City, United States Senior Director
Same function Same seniority Same country
60%similar
Amgen Inc. South San Francisco, United States Senior Director
Same function Same seniority Same country
60%similar
Amgen Inc. Thousand Oaks, United States Senior Director
Same function Same seniority Same country
60%similar
Gilead Sciences, Inc. Foster City, United States Senior Director
Same function Same seniority Same country
60%similar
Merck Rahway, New Jersey, United States of America Senior Director
Same function Same seniority Same country
60%similar
Lilly San Francisco, California, United States of America Senior Director
Same function Same seniority Same country

Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Senior Director, Discovery Sciences & Technologies
Gilead Sciences, Inc. · Foster City, United States · Senior Director
Function Therapeutic area Seniority Country
60%
Sr Director, Analytical Development
Gilead Sciences, Inc. · Foster City, United States · Senior Director
Function Therapeutic area Seniority Country
60%
Director/Sr. Director – Medicinal Chemistry (synthetic macrocycles)
Lilly · Indianapolis, Indiana, United States of America · Senior Director
Function Therapeutic area Seniority Country
60%
Sr Director, Analytical Operations
Gilead Sciences, Inc. · Foster City, United States · Senior Director
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.