Senior Director, CMC Team Leader

Working with Us

Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through   science. In oncology, hematology, immunology ,   cardiovascular , and   neuroscience   disease – and one of the most diverse   and promising pipelines in the industry – each of our passionate colleagues   contribute   to innovations that   drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a   difference.

The Scientific Director, CMC Team   Leader   is responsible for   developing and leading   the   execution of   comprehensive,   compound-specific   CMC   strategies   t o   meet   global   R&D   project needs .   Supporting the Product Development portfolio, which includes small molecule s , large   molecules   and new modalities   (conjugates,   peptides   and oligonucleotides) , this unique role   is critical to our   role   turning molecules into medicines.

Primary r esponsibilities of the S cientific   Director , CMC Team Leader :

Leads   the   interdisciplinary matrix teams responsible for developing and executing   compound-specific   integrated CMC strategies that   advance   R&D   Project Team   objectives   and   encompass   drug substance, drug product, analytical, quality, regulatory, and clinical   supplies .

Represents   the Global Product Development and Supply (GPS) organization on   key   R&D Project Teams, actively collaborates   across   functional areas   (Clinical, Commercial, Regulatory, Clinical Pharmacology, Toxicology, etc.)   and influence s   the BMS organization to develop globally optimized   program strategies .

Communicates and partners effectively   across   functional areas within Product Development and other stakeholders (Quality, Toxicology, DMPK, Clinical Pharmacology, Regulatory CMC, Commercial Manufacturing, etc.) to define and execute   the   CMC strategy for the project.   Identifies   and escalates key issues ,   risks   and   resource allocation needs, as appropriate

Accountable for   managing   multiple assets   across   large   and s mall molecule s ,   ranging   across phases of development   from candidate nomination, First-in-Human,   and   pivotal   clinical studies ,   through   to   market application approvals   (BLA, NDA)   in partnership with CMC Team Project Manager .

Accountable for   CMC Project budget   and applies financial acumen to evaluate portfolio trends and   anticipate   the impact of strategic inflection points on project trajectories .   Works with a ‘return on investment’ mindset to define project opportunities,   seeking   to   optimize   PDs impact within the broader portfolio.

Influences CMC regulatory strategies and c ritically reviews relevant documents, including but not limited to all CMC regulatory submissions, briefing booklets,   and   information requests .

Champions operational excellence by driving the adoption of best practices and spearheading strategic improvement initiatives , including the adoption of advanced digital capabilities, planning   tools   and program simulation .   P artner s   with the   GPS   Business   D evelopment group   to support Due Diligence evaluations and activities to bring   assets   into the GPS network   and   partner with alliance management ,   as necessary.

Skills/Knowledge Required – Senior Director:

Advanced degree in relevant scientific discipline

1 5 + years of relevant CMC experience in the pharmaceutical industry.

Robust   understanding of how CMC integrates and partners with Non-Clinical and Clinical development, Quality, Regulatory,   Commercial   and other functional areas in pharmaceutical development.

Capable of thinking critically and developing strategic plans that align with long-term business   objectives   and drive innovation.

Excellent verbal and written communication, as well as strong problem-solving, and decision-making skills.

Proven track record of influencing and building strong partnerships with stakeholders across the organization to achieve strategic goals.

Keen sense for value of investment with a proven   track record   of   applying risk-balanced and differential investment principles to enhance CMC operations and drive organizational success .

Demonstrated ability to lead, inspire, and develop high-performing teams while fostering a collaborative and inclusive team culture.

Ability to manage ambiguity and make decisions with limited information, when   required

Experience in multiple modalities   (e.g., biologics, small molecules, antibody-drug conjugates) is a clear plus.

Broad   and deep   understanding of chemical and/or biological, formulation and analytical development and a proven   track record   of l eading CMC teams throughout the development lifecycle, from early-stage development through commercialization

Experience working with external manufacturing organizations (CMOs) and managing complex supply chains and   budget .

Demonstrated success in developing and/or applying innovative solutions to complex CMC technical challenges.

Strong knowledge of global regulatory guidelines and requirements (e.g., FDA, EMA, ICH guidelines).

Embraces BMS   shared values of passion, innovation, urgency, accountability, inclusion, and integrity

Skills/Knowledge Required   - Director :

Advanced degree in   relevant scientific discipline

12+ years of relevant CMC experience in the pharmaceutical industry.

Solid understanding of how CMC integrates and partners with Non-Clinical and Clinical development, Quality, Regulatory,   Commercial   and other functional areas in pharmaceutical development.

E xceptional verbal and written communication skills with a proven ability to influence and align stakeholders across all levels and functions within a complex matrix environment, including both internal and external partners.

Keen sense for value   and understanding   of investment   strategy ,   ability to apply risk-balanced and differential investment principles to enhance CMC operations and drive organizational success

Capable of thinking critically and developing strategic plans that align with long-term business   objectives   and drive innovation.

A bility to manage ambiguity and make decisions with limited   information,   when   required .

Demonstrated ability to   operate   as an enterprise leader,   driving   clarity and influence to   advance   business   objectives

Broad understanding of chemical   and/or   biological,   formulation   and   analytical developm ent and a proven   track record   in   CMC development   and/or leading CMC teams throughout the development lifecycle, from early-stage development through commercialization .

Experience in multiple   modalities   ( e.g.,   biologics, small molecules,   antibody-drug conjugates )   is a clear plus.

Relevant strategic and tactical project leadership experience , a bility to l ead empowered, highly collaborative   matrix   teams with shared vision, value ,   and purpose

Embrace s   BMS   shared values of passion, innovation, urgency, accountability, inclusion ,   and integrity

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Compensation Overview:

New Brunswick - NJ - US: $234,100 - $283,672


The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/.

Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:

Health Coverage: Medical, pharmacy, dental, and vision care.

Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).

Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.

​ Work-life benefits include:

Paid Time Off

US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)

Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays

Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.

All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

*Eligibility Disclosure: T he summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ eeo -accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:  https://careers.bms.com/california-residents/

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection .

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at TAEnablement@bms.com . Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response. Inquiries related to the status of your application should be directed to Chat with Ripley.

R1604331 : Senior Director, CMC Team Leader