(Senior-) Director Clinical Development - Late Stage & ADC Oncology (Mainz, RP, DE, 55116)
Notify me about similar jobsAbout this opportunity
Munich, Germany; London, United Kingdom; Mainz, Germany | full time | Job ID: 11648
About the Role
As a (Senior) Director of Clinical Development at BioNTech, you will collaborate closely with the VP of Clinical Development to drive innovative strategies for assigned programs. In this pivotal role, you will oversee the design and execution of clinical trials across all phases, ensuring data integrity, patient safety, and regulatory approval. Leveraging your deep expertise in Immuno-Oncology and Oncology, you will lead matrix teams to deliver impactful results while guiding decisions with scientific rigor and medical insight. Join us to shape the future of medicine through cutting-edge research and development.
Your Contribution
Lead clinical trial design to develop plans for new compounds from early exploratory studies through late-stage development and regulatory approval.
Collaborate with the VP to operationalize clinical strategies for assigned portfolios and ensure alignment across functions.
Serve as Program Lead, guiding core teams, driving program strategy, and preparing submission processes.
Ensure patient safety by overseeing medical aspects of studies, conducting risk-benefit assessments, and addressing medical queries.
Innovate in trial design, leveraging digital endpoints and real-world evidence to enhance study outcomes.
Develop key clinical documents, including Investigator’s Brochures, NDAs, and high-quality Clinical Study Reports.
Build strong relationships with external stakeholders while representing the team in governance meetings.
A Good Match
M.D. degree with a robust scientific and clinical background in Immuno-Oncology or Oncology.
Extensive experience leading clinical development programs across Phases I–III, including NDA submissions.
Expertise in advanced clinical study designs, companion diagnostics for patient selection, translational modeling, biostatistics, and confirmatory Phase III trial design.
Proven experience interacting globally with health authorities (e.g., EMA, FDA), with successful registration being advantageous.
Strong medical acumen in monitoring safety/efficacy data and managing patient-centric drug development processes.
Exceptional leadership skills to mentor teams while accelerating capabilities through situational management styles.
BioNTech offers a collaborative environment where innovation meets purpose. If you are passionate about advancing therapies that make a difference in patients' lives, we invite you to join our mission-driven team.
Expected Pay Range: $168,100-$318,300 plus benefits, annual bonus & equity (bonus and equity is variable and dependent on company and individual performance). *Compensation for the role will depend on several factors, including responsibilities of the job, education, experience, knowledge, skills, and abilities.
Your Benefits:
It's our priority to support you:
Your flexibility: flexible hours | vacation account
Your growth: Digital Learning | Performance & talent development | leadership development | Apprenticeships | LinkedIn Learning
Your value: Your voice at the table | Culture on an equal footing | Opportunities to shape & impact | Support for your full potential
Your health and lifestyle: Company bike
Your mobility: Job ticket | Deutschlandticket
Your life phases: Employer-funded pension | Childcare
Apply now - We look forward to your application!
Apply to our Munich, Germany; London, United Kingdom; Mainz, Germany location by sending us your documents via our online form. For any questions, contact our talent acquisition team on: + 49 (0) 6131-9084-1291 (Monday-Friday from 1 PM to 3 PM CET).
Job ID 11648 (please always specify if you have any questions)
By submitting your application, you acknowledge that a background check will be conducted as part of the recruitment process in accordance with applicable laws and regulations. If you are considered for the position, BioNTech will conduct the background check through our service provider ‘HireRight’. You will be informed accordingly by your BioNTech-Recruiter.
]]>
Job details
How this role compares
Computed from every other active Clinical Development role in our database, not just this employer's listings.
We currently track 253 comparable Director Clinical Development roles across 50 biopharma companies.
Salary context
119 of 253 peers report a salary range (USD, annualized)
Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.
Where these roles are based
Top locations among the 253 comparable roles
+ 11 more countries
Seniority mix
253 of 253 peers have a known seniority level
Therapeutic area mix
74 of 253 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden
Similar opportunities
The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.
Open in 2 locations
Notify me about similar jobs
Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.
How we calculate "similar"
No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.
Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.
0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.