Roche Posted August 20, 2026

Senior Bioinformatics Scientist

Pleasanton, California, United States of America Full time
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Roche has closed or removed this posting -- see current similar openings below.

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About this opportunity

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

We are seeking a talented and highly motivated Senior Bioinformatics Scientist to support the development of Roche Diagnostics Molecular Assays that have a global impact on patient care. This role requires a broad understanding of assay development across diverse technologies, including NGS, Nanopore sequencing, and PCR. The successful candidate will collaborate closely with bioinformaticians, wet lab scientists, and external customers to design, implement, and maintain internal algorithms and tools for clinical diagnostic assay development.

The Opportunity:  

Collaborate with multidisciplinary teams of molecular and computational biologists, as well as wet lab scientists, to design, optimize, and troubleshoot advanced high-throughput sequencing assays and workflows for clinical diagnostic applications.

Contribute bioinformatics expertise throughout the assay development lifecycle, including initial sequencing, validation, and production implementation, by developing and maintaining analytical tools and pipelines for processing diagnostic data from tumor, germline, and cell-free DNA samples.

Create, implement, and streamline bioinformatics tools and workflows in partnership with wet lab scientists to enhance assay development efficiency and data quality.

Provide hands-on troubleshooting to ensure data quality, integrity, and accessibility across the diagnostic workflow, while addressing the needs of internal and external stakeholders through scientific and business analyses.

Advocate for best practices in documenting, training, and scaling algorithms, tools, and workflows to ensure reproducibility and scalability.

Communicate project outcomes and team progress across various teams and organizational functions to promote alignment and collaboration.

Who You Are:  

Required: You have a Bachelor's Degree and 7+ years of experience

Preferred: You have a PhD in Bioinformatics, Computational Biology, Statistics, or a related field with 2 years of industry experience in clinical diagnostics or related domain or a Masters degree in Bioinformatics, Computational Biology, Statistics, or a related field with 5 years of industry experience in clinical diagnostics or a related domain

You have expertise in DNA/RNA sequencing data analysis and interpretation.

You have a strong understanding of molecular biology principles and hands-on familiarity with next-generation sequencing laboratory processes.

Behaviors, competencies, and qualities of the ideal applicant.

You are proficient in programming skills in R and/or Python, with experience working in a distributed Linux environment. ( Proficiency in C++ or Java is a plus)

You are proficient in creating clear, insightful visualizations of complex biological data, with strong presentation skills

You are skilled in writing and maintaining bioinformatics workflows using workflow management systems such as Snakemake or Nextflow

You have a solid understanding of cancer biology and in vitro diagnostics (IVD).

​ Relocation benefits are not available for this posting.

The expected salary range for this position based on the primary location of California is $ 102,100 - $167 7850 . Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  A discretionary annual bonus may be available based on individual and Company performance.  This position also qualifies for the benefits detailed at the link provided below.

Benefits

 

 

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants .

Job details

Seniority
Senior
Function
Biostatistics & Data Science
Therapeutic area
Not listed
Location
Pleasanton, California, United States of America
Employment type
Full time

How this role compares

Computed from every other active Biostatistics & Data Science role in our database, not just this employer's listings.

We currently track 114 comparable Senior Biostatistics & Data Science roles across 27 biopharma companies.

114Comparable roles tracked
104Currently active
27Companies hiring similar roles
15Countries represented

Salary context

54 of 114 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Lowest disclosed · Principal Computational Statistician · Lilly $66,000/yr – $193,600/yr
Highest disclosed · Biostatistics Associate Director (HYBRID) · Vertex Pharmaceuticals Inc (US) $174,800/yr – $262,200/yr
Peer group range $129,800 – $218,500 (median $185,913)

Where these roles are based

Top locations among the 114 comparable roles

United States71
United Kingdom6
Switzerland5
India5
Canada4
Japan4

+ 9 more countries

Seniority mix

114 of 114 peers have a known seniority level

Senior43
Principal37
Associate Director34

Therapeutic area mix

10 of 114 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Immunology4
Oncology3
Rare Disease2
Cardiovascular / CVRM1

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How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

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Function Therapeutic area Seniority Country
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Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.