Scientist, Proteins, Analytical Development
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At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com .
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Job Function:
Discovery & Pre-Clinical/Clinical Development
Job Sub Function:
Biotherapeutics R&D
Job Category:
Scientific/Technology
All Job Posting Locations:
Malvern, Pennsylvania, United States of America
Job Description:
About Innovative Medicine
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
Learn more at https://www.jnj.com/innovative-medicine
We are searching for the best talent for a Scientist, Proteins, Analytical Development.
Purpose: The Therapeutics, Development & Supply (TDS), Proteins Analytical Development (AD) is recruiting for a Scientist who will conduct peptide mapping method development and qualification activities on monoclonal antibodies, bi- and tri-specific antibodies and antibody drug conjugates.
You will work and grow in an environment that values innovation, leadership, scientific excellence, urgency, and personal accountability.
You will be responsible for:
Operate state-of-the-art LC and MS instrumentation
Learn and apply different software packages for LCMS/protein analysis
Perform LCMS-based quantitation of post-translational modifications
Design and implement peptide mapping / MS experiments on antibodies and recombinant proteins to assess sequence coverage and sites of modification
Participate in IND, IMPD, BLA, and other regulatory filings
Develop test methods, provide documentation and write scientific reports.
Conduct testing to support analytical development, manufacturing process development, process validations, and manufacturing investigations
Lead or facilitate technical discussions and participate in cross-functional teams at project-related meetings
Qualifications / Requirements:
Education:
A master’s degree with 5+ years, or a bachelor’s degree with 9+ years of relevant biochemical experience
Experience and Skills:
Required:
Proven scientific expertise with extensive hands-on experience with LC-MS
Knowledge of method robustness, method design and familiarity with assay validation parameters
Excellent organization, communication, presentation skills and scientific/technical writing skills
Proficiency at running and trouble-shooting assays
Able to manage multiple tasks, handle tight timelines and deliver quality data
Preferred:
Experience peptide mapping method development and qualification activities on monoclonal antibodies, bi- and tri-specific antibodies and antibody drug conjugates
Excellent interpersonal skills
Experience with commercialization of therapeutic proteins
An understanding and experience in the application of various GXP concepts
Experience preparing reports, protocols and SOPs
Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers , internal employees contact AskGS to be directed to your accommodation resource.
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Required Skills:
Preferred Skills:
Analytical Reasoning, Biochemistry, Chemistry, Manufacturing, and Control (CMC), Coaching, Collaboration, Conducting Experiments, Data Quality, Drug Discovery Development, Molecular Diagnostics, Patent Applications, Pharmacogenetics, Report Writing, Research Documents, Scientific Research, Technologically Savvy, Written Expression
Job details
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