Scientist, mRNA Formulation

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Scientist, mRNA Formulation

Join GSK as a Scientist focused on mRNA formulation, where you will design and develop innovative mRNA delivery systems that support our vaccine and medicine discovery programs. Working closely with colleagues across disciplines, you will lead laboratory studies that enhance product understanding and accelerate development. We value curious, motivated scientists who take ownership, communicate clearly, and thrive in a collaborative environment. This role offers you a chance to grow your skills, make a meaningful impact, and contribute to GSK’s mission of uniting science, technology, and talent to get ahead of disease together.

This role is located Cambridge, MA in the United States and requires working on-site. Hybrid or remote work options are not available for this position.

This role will provide YOU the opportunity to lead key activities to progress YOUR career.  These responsibilities include some of the following :

Design, prepare, and evaluate mRNA formulations and delivery systems, including lipid nanoparticle (LNP) platforms, to assess stability, compatibility, encapsulation efficiency, and performance.

Develop and execute formulation studies, stability studies, and stress studies to advance mRNA vaccine and therapeutic programs.

Characterize physicochemical properties of mRNA formulations using analytical techniques such as dynamic light scattering (DLS), zeta potential, chromatography, and thermal analysis.

Analyze and interpret experimental data, identify formulation risks and opportunities, and recommend strategies to improve product quality, stability, and performance.

Collaborate closely with analytical, process development, regulatory, and quality teams to support project goals and advance development programs.

Maintain accurate laboratory records, prepare study reports, and communicate scientific findings through presentations and technical documentation.

Maintain the drug product laboratory space in a safe, organized, and inspection-ready manner.

Support troubleshooting and problem-solving efforts to address formulation challenges.

 

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

BS, MS, or PhD in Pharmaceutical Sciences, Pharmaceutics, Chemical Engineering, Chemistry, Biochemistry, Biomedical Engineering, or a related scientific discipline (BS and a minimum of 5 years of relevant experience, MS and a minimum of 3 years of relevant experience, or PhD and 0 years of relevant experience).

A minimum of 1 year of hands-on laboratory experience developing and evaluating mRNA-LNP formulations or other nucleic acid delivery systems.

 

Preferred Qualifications:

Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:

Advanced degree (Master’s or PhD) in a relevant discipline.

Experience with vaccine formulation, protein biologics, nanoparticle delivery systems, or other advanced drug delivery technologies.

Experience designing and executing formulation studies, stability studies, and other drug product development experiments.

Practical knowledge of lipid nanoparticle formulation development and characterization.

Knowledge of high-throughput formulation screening and stability study design.

Familiarity with process development, scale-up considerations and manufacturing handoffs.

Familiarity with characterization techniques used to evaluate formulation quality, such as dynamic light scattering, zeta potential measurement, or chromatography.

If you want to work on exciting challenges that help shape new medicines using mRNA technology, we encourage you to apply. Join us in making a difference in patients’ lives around the world. We value your unique perspective and invite all interested candidates to submit their application.

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Skills

Biotechnology, Cell Biology, Cross-Functional Teamwork, Data Quality, Following Instructions, Interpersonal Communication, Lab Maintenance, Life Science, Matrix Leadership, Proper Documentation, Scientific Presentations, Scientific Research, Scientific Writing

• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $89,925 to $149,875. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.

Please visit  GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

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GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

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