Scientist II, Fermentation Process Development – Recombinant Peptides
Notify me about similar jobsAbout this opportunity
Company Description
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube.
Job Description
AbbVie’s Biologics CMC organization develops processes to support the advancement and manufacture of biologic medicines. AbbVie is seeking a motivated fermentation scientist to contribute to the development of microbial processes for recombinant peptide production. The successful candidate will perform hands-on fermentation studies and help develop, optimize, and scale upstream processes for therapeutic peptides. This role will collaborate with colleagues in strain development, downstream processing, analytical development, and other functions to generate reliable data and support project goals.
Responsibilities
Independently design, execute, and interpret critical fermentation experiments to answer scientific questions and advance project goals.
Develop and optimize microbial cultivation and fermentation processes, including work with hosts such as Escherichia coli and yeast.
Evaluate the effects of media composition, inoculum conditions, feed strategies, induction conditions, temperature, pH, agitation, aeration, and dissolved oxygen on growth and product expression.
Operate, maintain, and optimize bench-scale bioreactors and support microscale, parallel, and scale-down fermentation studies.
Apply broad technical proficiency to troubleshoot experiments, instrumentation, and routine process issues; adapt or innovate protocols and techniques as project needs evolve.
Collaborate with strain-development colleagues to screen and characterize microbial clones and expression systems.
Analyze fermentation data, including growth, substrate use, process parameters, product titer, and yield, and place findings in the relevant scientific context.
Troubleshoot experiments and instrumentation, adapting or developing methods to meet changing project needs.
Collaborate with strain-development, downstream-processing, and analytical teams to assess expression, peptide recovery, and product quality.
Consult relevant scientific literature and use it to inform experimental design, interpret findings, and solve technical problems.
Set and meet experimental timelines, communicate plans and results, contribute to technical documentation, and improve laboratory methods and operations.
Follow applicable corporate standards for conduct, safety, material handling, and GxP compliance, as relevant to the work.
Qualifications
Master’s degree or equivalent with 5+ years of relevant experience or Bachelor’s degree or equivalent with 7+ years of relevant experience, is required.
Theoretical and practical knowledge of microbial cultivation and fermentation, preferably using E. coli and/or yeast.
Demonstrated ability to independently design, execute, and interpret critical experiments to answer scientific questions.
Demonstrated ability to develop, adapt, and optimize experimental methods and techniques in response to project needs.
Experience operating bioreactors and applying fermentation parameters such as pH, temperature, agitation, aeration, and dissolved oxygen.
Ability to troubleshoot experiments and instrumentation, recognize significant deviations, and determine appropriate follow-up work.
Strong scientific writing, verbal communication, data interpretation, and presentation skills.
Ability to consult and apply relevant scientific literature and to communicate findings in the context of project objectives.
Ability to manage multiple assignments, meet timelines, and work effectively with cross-functional collaborators.
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html
Job details
How this role compares
Computed from every other active Manufacturing & CMC role in our database, not just this employer's listings.
We currently track 3374 comparable Manufacturing & CMC roles across 173 biopharma companies.
Salary context
792 of 3374 peers report a salary range (USD, annualized)
Peers share this role's job function. This posting doesn't list a seniority level, so peers aren't narrowed by seniority either -- the range below may span more levels than usual.
Where these roles are based
Top locations among the 3374 comparable roles
+ 55 more countries
Seniority mix
1484 of 3374 peers have a known seniority level
Therapeutic area mix
21 of 3374 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden
Similar opportunities
The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.
Notify me about similar jobs
Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.
Or follow a whole field: get every new Manufacturing & CMC job in the United States, and choose locations and companies.
How we calculate "similar"
No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.
Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.
0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.