Amgen Inc. Posted October 28, 2026

Reliability / Asset Performance Management Business Owner

Thousand Oaks, United States Full time
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Amgen Inc. is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Career Category

Engineering

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission, to serve patients living with serious illnesses, drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity-related conditions, rare diseases, inflammatory conditions and cancer.  As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Reliability / Asset Performance Management Business Owner

What you will do

Let’s do this. Let’s change the world. In this vital role you own the global business capability, roadmap, governance, and continuous improvement of reliability processes enabled by SAP Asset Performance Management and integrated SAP EAM processes. The role ensures APM is adopted as an operating capability that converts asset data, failure insights, criticality, condition monitoring, and reliability studies into actionable maintenance strategy improvements.

Key responsibilities

·       Actively participate on the Global reliability network to provide insights on equipment performance.

·       Define and maintain the global SAP APM product vision, business roadmap, release priorities, and value realization plan.

·       Own the APM business backlog, including enhancement intake, prioritization, user story definition, process acceptance criteria, and release readiness.

·       Establish standard reliability workflows for criticality assessment, failure mode analysis, RCM/FMEA, reliability recommendations, strategy updates, and recurring problem escalation.

·       Ensure APM is integrated with SAP EAM work management, asset hierarchy, equipment records, maintenance plans, task lists, failure codes, notification/order history, and performance reporting.

·       Partner with master data governance to define required asset attributes, classifications, failure libraries, criticality data, and condition-monitoring links needed for reliable APM outputs.

·       Drive cross-site standardization so reliability studies, risk ranking, maintenance strategy decisions, and performance insights are not developed independently at each site.

·       Lead business validation for APM-related configuration, integrations, dashboards, role design, training content, and process documentation.

·       Translate APM insights into actionable maintenance strategy changes, including PM optimization, predictive/condition-based maintenance opportunities, and reliability improvement initiatives.

·       Include Plant Pulse details into APM design and future roadmap.

·       Provide reliability requirements for future Plant Pulse development in order and leverage enterprise iiOT capabilities for the asset performance monitoring process for critical assets.

·       Monitor adoption and value realization through global KPIs, including APM usage, data completeness, recurring asset issue visibility, maintenance strategy effectiveness, and reliability performance trends.

Key interfaces

·       Site reliability engineers and maintenance leaders

·       SAP EAM process owners, planners, schedulers, and maintenance execution teams

·       Asset master data governance, PiLog/data quality teams, and SAP functional/IT teams

·       Quality, engineering, automation, operations, and capital project stakeholders

·       Global Reliability Network, Global EAM Council, and site change agent network

·       Global Plant Pulse integration to the APM process.

·       AIN data analytics team.

Success measures

·       Consistent APM adoption and reliability process execution across sites.

·       Improved completeness and quality of asset, failure, criticality, and maintenance strategy data.

·       Increased use of APM insights to update maintenance plans, task lists, PM intervals, and reliability actions.

·       Reduced fragmented site-by-site reliability approaches and improved reuse of global standards and best practices.

·       Improved visibility to bad actors, recurring failures, asset risks, and maintenance strategy effectiveness.

·       Measurable contribution to equipment availability, reliability performance, operational capacity, and audit-ready decision traceability.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is an individual with these qualifications.

Basic Qualifications:

Doctorate degree

OR

Master’s degree and 2 years of Engineering experience

OR

Bachelor’s degree and 4 years of Engineering experience

OR

Associate’s degree and 8 years of Engineering experience

OR

High school diploma / GED and 10 years of Engineering experience

Preferred Qualifications:

Strong understanding of maintenance, reliability engineering, asset management, and regulated manufacturing operations.

·       Experience with SAP EAM, SAP APM, CMMS data, work management, failure coding, criticality assessment, RCM, FMEA, and maintenance strategy optimization.

·       Ability to translate business requirements into product backlog items, process standards, user stories, test scenarios, and adoption plans.

·       Strong cross-functional leadership, stakeholder management, facilitation, and change leadership skills.

·       Working knowledge of asset management and reliability standards such as ISO 55000, SAE JA1012, IEC 60812, and failure data taxonomy concepts is preferred.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

Stock-based long-term incentives

Award-winning time-off plans

Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

 

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

 

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer. We make all employment decisions without regard to race, color, religion, sex or any other characteristic protected by applicable law.

We provide reasonable accommodations to applicants and employees with disabilities, consistent with legal requirements. Please contact us to request accommodation.

. Salary Range

115,494.60USD -156,257.40 USD

Job details

Seniority
Not listed
Function
Manufacturing & CMC
Therapeutic area
Not listed
Location
Thousand Oaks, United States
Employment type
Full time

How this role compares

Computed from every other active Manufacturing & CMC role in our database, not just this employer's listings.

We currently track 3428 comparable Manufacturing & CMC roles across 175 biopharma companies.

3428Comparable roles tracked
3174Currently active
175Companies hiring similar roles
61Countries represented

Salary context

813 of 3428 peers report a salary range (USD, annualized)

Peers share this role's job function. This posting doesn't list a seniority level, so peers aren't narrowed by seniority either -- the range below may span more levels than usual.

This roleSubject Not listed on this posting
Lowest disclosed · Operator – Plant Utilities · Lilly $13/hr – $28/hr (≈ $26,998–$58,302/yr)
Highest disclosed · Head of Analytical Development · ModernaTX, Inc. $272,200/yr – $490,100/yr
Peer group range $42,650 – $381,150 (median $127,400)

Where these roles are based

Top locations among the 3428 comparable roles

United States1570
Germany211
India155
France149
Ireland129
China125

+ 55 more countries

Seniority mix

1516 of 3428 peers have a known seniority level

Senior408
Manager359
Intern/Fellow/Postdoc208
Associate149
Principal129
Associate Director105
Director104
Senior Director48
Executive/VP6

Therapeutic area mix

22 of 3428 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Vaccines & Infectious Disease13
Rare Disease3
Dermatology & Aesthetics2
Oncology2
Immunology1
Respiratory1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

40%similar
40%similar
Lilly Indianapolis, Indiana, United States of America Director
Same function Same country
40%similar
Lilly Indianapolis, Indiana, United States of America Associate
Same function Same country
40%similar
Merck West Point, Pennsylvania, United States of America Principal
Same function Same country
40%similar
Merck West Point, Pennsylvania, United States Intern/Fellow/Postdoc
Same function Same country
40%similar
AbbVie North Chicago, IL Associate Director
Same function Same country

Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

Or follow a whole field: get every new Manufacturing & CMC job in the United States, and choose locations and companies.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

40%
Director, Global Regulatory Affairs – Chemistry, Manufacturing and Controls (CMC), Platform Innovation – Synthetic Peptides and Oligonucleotides
Lilly · Indianapolis, Indiana, United States of America · Director
Function Therapeutic area Seniority Country
40%
Associate Principal Scientist/Engineer, Medical Device and Combination Products, Analytical
Merck · West Point, Pennsylvania, United States of America · Principal
Function Therapeutic area Seniority Country
40%
Senior Scientist II - Biologics Drug Product Development
AbbVie · North Chicago, IL · Senior
Function Therapeutic area Seniority Country
40%
Senior Scientist, II Biologics & Genetic Medicine - LCMS Characterization & Bioanalysis
AbbVie · North Chicago, IL · Senior
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.