Regeneron Pharmaceuticals, Inc (USA) Posted October 6, 2026

Principal Scientist - Precision Medicine

Tarrytown, United States Full time
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Regeneron Pharmaceuticals, Inc (USA) is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Principal Scientist, Precision Medicine (Biomarker) Strategy Lead

Precision Medicine

Build our future together:

The Precision Medicine department at Regeneron is responsible for designing and executing the overarching translational and clinical biomarker strategies for therapeutic candidates during clinical development. We are seeking to hire a Precision Medicine Strategy Lead at the Principal Scientist level focusing on solid tumor oncology, heme malignancies, and immune oncology.

In this highly matrixed role, the Principal Scientist will be responsible for defining the key scientific questions relating to the drug target mechanism of action, disease biology and prognostic biomarkers associated with disease heterogeneity and severity, as well as informing potential patient stratification or selection. This information will guide development of a robust Precision Medicine strategy.

When & where:

Location: Tarrytown, NY United States

Discover your role:

Leading focused assay development and implementation of assays and associated sample collections throughout a clinical trial.

Coordinating data analysis through collaboration with computational scientists involved in integrating multi-omic data: genomics, transcriptomics, and proteomics.

Interpreting results and leading communication of the key impact of the data to guide decision making to inform the clinical development strategy.

Enabling advances in target identification, indication selection, early indication of biological activity and patient stratification/selection.

Partnering cross-functionally across Research, Clinical Development, Clinical Pharmacology, Companion Diagnostics, Biostatistics, and Clinical Operations to ensure seamless scientific alignment.

Managing internal and external research collaborations to enable development of clinical fit for purpose assays and translational research.

Contributing to technical reports, study memos, clinical study reports, and scientific publications.

This role requires:

The ability to drive, manage, execute and deliver timely results for complex scientific projects.

Strong communication and presentation skills.

A strategic understanding of the application of biomarker technologies to basic, translational or clinical research.

Demonstrated ability to effectively collaborate and work in cross-functional teams.

A Ph.D., M.D., or MS and 4-7 years' experience participating effectively on cross-disciplinary teams in pharmaceutical or biotech.

#PMSL

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all  qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate.  The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits.  Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/ . For other locations, additional information will be provided during the recruitment process.  If you have any questions, please speak with your recruiter.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)

$128,600.00 - $210,000.00

Job details

Seniority
Principal
Function
Clinical Development
Therapeutic area
Not listed
Location
Tarrytown, United States
Employment type
Full time

How this role compares

Computed from every other active Clinical Development role in our database, not just this employer's listings.

We currently track 440 comparable Principal Clinical Development roles across 66 biopharma companies.

440Comparable roles tracked
399Currently active
66Companies hiring similar roles
35Countries represented

Salary context

183 of 440 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $128,600/yr – $210,000/yr
Peer group range $0 – $392,100 (median $251,050)

Where these roles are based

Top locations among the 440 comparable roles

United States275
India37
United Kingdom29
China10
Switzerland9
Germany8

+ 29 more countries

Seniority mix

440 of 440 peers have a known seniority level

Director251
Senior149
Principal40

Therapeutic area mix

96 of 440 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology53
Neuroscience13
Immunology9
Cardiovascular / CVRM8
Respiratory6
Dermatology & Aesthetics3
Ophthalmology2
Vaccines & Infectious Disease1
Rare Disease1

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The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
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Same function Same seniority Same country
60%similar
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60%similar
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Same function Same seniority Same country

Notify me about similar jobs

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How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

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Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.