GlaxoSmithKline Services Unlimited Posted September 17, 2026

Principal Scientist

Uk, United Kingdom Full time
Data & Digital Principal
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About this opportunity

Principal Scientist

Closing Date: 1st October 2026 (COB)

Business Introduction

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.

Find out more:

Our approach to R&D

For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029 .

Position Summary

You will lead and deliver high-impact biomarker and mechanism-of-action research to support clinical translation. You will work across teams to design experiments, analyse data, and translate findings into biological hypotheses. We value clear thinking, scientific curiosity, collaboration, and practical problem-solving. This role offers strong growth potential, the chance to shape scientific direction, and meaningful impact aligned with our mission of uniting science, technology and talent to get ahead of disease together.

Responsibilities

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

- Develop and maintain computational pipelines to support translational research.

- Interpret complex datasets and present clear, actionable insights to project teams.

- Lead cross-functional project activities and mentor junior scientists.

- Ensure high standards for data integrity, documentation and reproducibility.

- Contribute to scientific reports, presentations and peer-reviewed publications.

Why You?

Basic Qualification

We are seeking professionals with the following required skills and qualifications to help us achieve our goals:

- PhD or MSc in Bioinformatics, Computational Biology, or related field and post-graduate experience.

- Experience in analysis of bioimaging data or single-cell sequencing data analysis.

- Proficiency in at least one programming language used for data analysis, Python or R.

- Strong statistical understanding and experience analysing biological datasets.

- Experience working in multidisciplinary teams and communicating results to non-specialists.

- Right to work in the United Kingdom; willing to work on-site or hybrid as required by the team.

Preferred Qualification

If you have the following characteristics, it would be a plus:

- Familiarity with single-cell sequencing, proteomics or advanced bioimaging data.

- Track record of publications or conference presentations in relevant scientific areas.

- Experience building automated pipelines and applying machine learning in biology.

- Demonstrated leadership of projects and mentoring of junior staff.

Work Pattern

This position is offered as hybrid working, combining time on-site in the United Kingdom or Germany with flexible remote work. Specific on-site versus remote days will be agreed with the hiring manager.

What we value

We create a workplace where people can grow and do their best work. We welcome different perspectives and foster inclusion. We look for people who are curious, collaborative and accountable. If you want to help translate genetics into better medicines and grow your scientific leadership, we would love to hear from you.

How to apply

Please submit your CV and a short statement (up to 300 words) describing how your skills match this role and what you hope to achieve in this position. We encourage applications from people with a range of backgrounds and experiences. Apply now and take the next step in your career.

Skills

Applied Statistics, Data Analysis, Data Engineering, Data Science, Datasets, Drug Development, Drug Discovery Process, Drug Target Identification, Genetic Analysis, Genomic Analysis, Machine Learning (ML), Software Engineering

Germany Salary Range / Gehaltsbandbreiten Deutschland: EUR 74,250 to EUR 123,750The annual gross base salary range for new hires in this position is listed above for each applicable location. These ranges take into account a number of factors including the candidate’s skills, experience, education level and the market rate for the role. In addition, this position may offer an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. More detailed information on the total benefits package will be supplied during the recruitment process. This role is available for applicants from multiple locations, and therefore salary ranges for certain locations are also shown. Salary ranges for other locations are shown because some markets have pay transparency laws that require salary information on job postings, and those locations are potential job sites for this role. If salary ranges are not displayed in the job posting for a specific location or country, the relevant compensation will be discussed during the recruitment process. Please note salaries vary by country based on the candidate’s skills, experience, education level and the market rate for the role. Offers are typically made within the advertised range based on the candidate’s skills, experience and qualifications, with the upper end generally reserved for highly experienced candidates or other exceptional circumstances aligned with these criteria.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at UKRecruitment.Adjustments@gsk.com where you can also request a call.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a  Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Job details

Seniority
Principal
Function
Data & Digital
Therapeutic area
Not listed
Location
Uk, United Kingdom
Employment type
Full time

How this role compares

Computed from every other active Data & Digital role in our database, not just this employer's listings.

We currently track 68 comparable Principal Data & Digital roles across 17 biopharma companies.

68Comparable roles tracked
63Currently active
17Companies hiring similar roles
10Countries represented

Salary context

18 of 68 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Lowest disclosed · Principal Statistical Programmer · Regeneron Pharmaceuticals, Inc (USA) $109,900/yr – $179,300/yr
Highest disclosed · Director, AI Foundations Engineer- Remote · Novartis $194,600/yr – $361,400/yr
Peer group range $144,600 – $278,000 (median $244,150)

Where these roles are based

Top locations among the 68 comparable roles

India32
United States21
United Kingdom5
Germany2
Portugal2
France2

+ 4 more countries

Seniority mix

68 of 68 peers have a known seniority level

Senior41
Director16
Principal11

Therapeutic area mix

0 of 68 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

No peers with a known therapeutic area yet.

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How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
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Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.