Merck Posted August 16, 2026

Principal Scientist, Drug Discovery

Rahway, New Jersey, United States of America FULL_TIME
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Merck is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Job Description

Join the Rahway, NJ Animal Health Team 

Our Company's Global Animal Health Research & Development (R&D) division is a pioneer in the discovery, development and registration of vaccines and therapeutics for animals.. To strengthen our team, we are looking for a highly skilled and motivated Principal Scientist to join our R&D team.

Purpose of the Role

The Principal Scientist, Drug Discovery in our Research and Development Department will be responsible for identifying new molecular entities and technologies for use in animal health from our Company Laboratories or from external partners such as human pharma or biotech companies as well as academia. The successful candidate will be a key driver to advance novel targets and will lead these research programs from ideation through the early research and proof-of-concept phase up to the development stage. She/he/they will interface with researchers and senior management throughout the organization as well as external partners and operate within a matrix structure to garner resources for the necessary research work (Medicinal and Process Chemistry, in vitro Pharmacology, Pharmacokinetics, Disease Models, Formulation Development, Safety & Toxicology).  The position will report directly to the Distinguished Scientist and Global Head, our Company's Research & Development Liaison and Discovery – Non-infectious Diseases.

Education:

Required: PhD and/or DVM/VMD, with Board certification in pharmacology

Required Experience:

Minimum of 8 years industry or pharmaceutical research experience in drug discovery or preclinical research with a focus on in vivo pharmacology

Advanced and thorough scientific knowledge in pharmacology, disease mechanisms and related preclinical models

Expertise in one of the following fields: oncology, diabetes, respiratory & immunology, cardiology, pain & inflammation, or reproduction.

Knowledge of regulatory aspects of pharmaceuticals including GLP, GCP and GMP

Ability to manage multiple projects, including budgets, contracts, and timelines

Ability to independently plan, recommend and complete research programs

Excellent communication and interpersonal skills

Effective creator of executive level presentations and documents

Experience in preparing patent applications in support of patent coverage of research efforts

10 % Travel

Preferred Experience:

Board certification in Pharmacology

Project management skills within pharmaceuticals

Experience in developing and managing collaborations with outsource providers, vendors, contractors and academic institutions

Experience in working with business development to identify and license external technology opportunities

Animal Health 

Our Animal Health Division is a trusted global leader in veterinary medicine, dedicated to preserving and improving health, well-being, and performance of animals and the people who care for them. We are a global team of professionals working together to make a positive difference in animal care and the world’s food supply and have a deep sense of responsibility towards our customers, consumers, animals, society, and our planet.

Through our commitment to The Science of Healthier Animals®, we offer veterinarians, farmers, pet owners and governments one of the widest ranges of veterinary pharmaceuticals, vaccines and health management solutions and services. We invest in dynamic and comprehensive R&D resources and a modern, global supply chain. We are present in more than 50 countries, while our products are available in some 150 markets.

Required Skills:

Adaptability, Communication, Detail-Oriented, Ethical Compliance, In Vivo Models, In Vivo Pharmacology, Leading Project Teams, Persuasion, Professional Networking, Science, Social Collaboration

Preferred Skills:

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.  As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.  For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement​

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

The salary range for this role is

$169,700.00 - $267,200.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits.  Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits .

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only:  We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only:  We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully 

Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

No

Travel Requirements:

10%

Flexible Work Arrangements:

Hybrid

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

N/A

Job Posting End Date:

09/28/2026 *A job posting is effective until 11:59:59PM on the day BEFORE  the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID:R363749

Job details

Seniority
Principal
Function
Drug Discovery & Preclinical Research
Therapeutic area
Not listed
Location
Rahway, New Jersey, United States of America
Employment type
FULL_TIME

How this role compares

Computed from every other active Drug Discovery & Preclinical Research role in our database, not just this employer's listings.

We currently track 231 comparable Principal Drug Discovery & Preclinical Research roles across 41 biopharma companies.

231Comparable roles tracked
219Currently active
41Companies hiring similar roles
13Countries represented

Salary context

89 of 231 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $169,700/yr – $267,200/yr
Peer group range $91,450 – $322,000 (median $183,250)

Where these roles are based

Top locations among the 231 comparable roles

United States181
India13
United Kingdom6
China5
Canada4
China's Mainland4

+ 7 more countries

Seniority mix

231 of 231 peers have a known seniority level

Senior110
Principal78
Director43

Therapeutic area mix

28 of 231 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology11
Neuroscience5
Cardiovascular / CVRM3
Immunology3
Respiratory3
Vaccines & Infectious Disease2
Gastroenterology1

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Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

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Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.