AbbVie Posted August 25, 2026

Principal Research Scientist II – Psychiatry Drug Discovery

Cambridge, MA Full-time
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AbbVie is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at  www.abbvie.com . Follow @abbvie on  LinkedIn,   Facebook ,  Instagram ,  X  and  YouTube.

Job Description

Overview 

We are seeking an experienced and highly motivated neuroscientist with strong drug discovery expertise to join our Discovery Psychiatry team. The successful candidate will apply drug discovery principles into exploratory through late-stage discovery programs and integrate knowledge across in vitro and in vivo electrophysiological approaches. Candidate must have a strong understanding of neural circuits, multimodal neurophysiological methodologies and translational utility. This role is an exciting opportunity to support psychiatry research from target validation, compound profiling, through clinical development in a dynamic, collaborative drug discovery environment.

Key Responsibilities 

Establish Drug Discovery framework in Psychiatry portfolio

Contribute to the development and implementation of research workflows that integrate complex multimodal datasets

Ensure alignment of development and discovery with broader cross-functional program team goals

Support strategic decision-making in psychiatry drug discovery

Provide scientific guidance and mentoring to junior scientists and research associates

Qualifications

Bachelor’s Degree in Science related field with 16 years of related work; Master’s Degree Science or PharmD with 14 years of related work; PhD in Science or related field with 8 years of related work experience.

Industry experience within early discovery for Psychiatry

Demonstrated experience with neurophysiology and/or functional approaches, including experience in the design and execution of studies investigating synaptic and circuit modulation relevant to psychiatric indications

Strong ability to work in cross-functional teams and effectively communicate scientific findings to both technical and non-technical audiences

Desired Qualifications 

Experience building translational frameworks or predictive approaches for functional biology data

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. ​

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.​

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit  https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Job details

Seniority
Principal
Function
Drug Discovery & Preclinical Research
Therapeutic area
Not listed
Location
Cambridge, MA
Employment type
Full-time

How this role compares

Computed from every other active Drug Discovery & Preclinical Research role in our database, not just this employer's listings.

We currently track 222 comparable Principal Drug Discovery & Preclinical Research roles across 42 biopharma companies.

222Comparable roles tracked
213Currently active
42Companies hiring similar roles
13Countries represented

Salary context

91 of 222 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $141,500/yr – $268,500/yr
Peer group range $91,450 – $322,000 (median $186,375)

Where these roles are based

Top locations among the 222 comparable roles

United States175
India11
China5
United Kingdom5
Spain4
China's Mainland4

+ 7 more countries

Seniority mix

222 of 222 peers have a known seniority level

Senior104
Principal79
Director39

Therapeutic area mix

25 of 222 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology8
Immunology4
Cardiovascular / CVRM4
Respiratory3
Neuroscience3
Vaccines & Infectious Disease2
Gastroenterology1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

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Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

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Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.