AbbVie Posted September 23, 2026

Operational Excellence Site Lead

Westport, MO Full-time
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About this opportunity

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at  www.abbvie.com . Follow @abbvie on  LinkedIn,   Facebook ,  Instagram ,  X  and  YouTube.

Job Description

The Operational Excellence Site Lead is responsible for leading the site operational excellence strategy, roadmap, and governance to improve performance across manufacturing, quality, supply chain, and support functions.

The role leads the OpEx team, builds site capability, standardises best practices, and embeds disciplined routines that support accountability, innovation, and sustainable continuous improvement.

Responsibilities:

Act as a trusted advisor to site leadership on operational excellence strategy, capability building, performance governance, and change execution.

Lead the site OpEx team, including work prioritisation, capability building, performance management, stakeholder engagement, and delivery of agreed business results.

Lead the site continuous improvement strategy and roadmap, ensuring alignment with business priorities, resource capacity, and measurable performance outcomes.

Coach and develop teams in Lean, Six Sigma, structured problem solving, visual management, standard work, value stream mapping, and daily management systems.

Identify, prioritise, and deliver high-impact improvement initiatives that reduce waste, improve flow, increase reliability, strengthen compliance, and support Right First Time performance.

Identify and deploy AI-enabled and digital solutions that improve decision-making, reduce manual effort, enhance productivity, and create scalable operational improvements.

Partner with site functions, senior leaders, regulatory agencies, vendors, and suppliers to support departmental and organisational objectives.

Establish and govern performance metrics, departmental budgets, improvement portfolios, benefits tracking, and accountability routines.

Ensure effective controls are in place so the department and improvement activities operate in compliance with applicable quality, regulatory, safety, environmental, EHS&E, and AbbVie Global policy requirements.

Make and execute support-function decisions from a strategic perspective, balancing operational requirements, risk, compliance, stakeholder input, resource allocation, and business impact.

Build a culture of continuous improvement, involvement, open communication, integrity, effective teamwork, Perfect Performance, and sustainable change across the site.

Qualifications

Bachelor’s degree in science, engineering, business, or a related discipline, with Lean Six Sigma Black Belt certification required and Master Black Belt certification preferred.

Minimum of eight years’ experience in pharmaceutical, biopharmaceutical, medical device, or similarly regulated manufacturing, including relevant managerial experience and delivery of strategic business projects.

Minimum of two years’ direct people management experience at management level, preferably leading an OpEx, digital, PMO, or project management function.

Strong technical capability in Lean, Six Sigma, operational excellence, structured problem solving, data analysis, process mapping, root cause analysis, mistake-proofing, standard work, visual management, performance management systems, and benefits tracking.

Proven experience identifying and applying AI, digital tools, and analytics to operational challenges, with clear evidence of measurable impact on performance, productivity, manual effort reduction, and decision-making speed.

Strong business acumen, with the ability to translate site challenges into prioritised improvement opportunities linked to enterprise goals, customer needs, financial impact, and sustainable performance outcomes.

Collaborative and credible leader who can influence across functions, communicate clearly, facilitate change, build capability in others, and maintain high standards of integrity, quality, compliance, and engagement through periods of change.

Additional Information

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit  https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Job details

Seniority
Not listed
Function
Manufacturing & CMC
Therapeutic area
Not listed
Location
Westport, MO
Employment type
Full-time

How this role compares

Computed from every other active Manufacturing & CMC role in our database, not just this employer's listings.

We currently track 3374 comparable Manufacturing & CMC roles across 173 biopharma companies.

3374Comparable roles tracked
3075Currently active
173Companies hiring similar roles
61Countries represented

Salary context

793 of 3374 peers report a salary range (USD, annualized)

Peers share this role's job function. This posting doesn't list a seniority level, so peers aren't narrowed by seniority either -- the range below may span more levels than usual.

This roleSubject Not listed on this posting
Lowest disclosed · Operator – Plant Utilities · Lilly $13/hr – $28/hr (≈ $26,998–$58,302/yr)
Highest disclosed · Head of Analytical Development · ModernaTX, Inc. $272,200/yr – $490,100/yr
Peer group range $42,650 – $381,150 (median $128,400)

Where these roles are based

Top locations among the 3374 comparable roles

United States1531
Germany216
India155
France145
Ireland130
China121

+ 55 more countries

Seniority mix

1484 of 3374 peers have a known seniority level

Senior403
Manager351
Intern/Fellow/Postdoc198
Associate142
Principal126
Director106
Associate Director104
Senior Director47
Executive/VP7

Therapeutic area mix

21 of 3374 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Vaccines & Infectious Disease13
Rare Disease3
Oncology2
Dermatology & Aesthetics1
Respiratory1
Immunology1

Currently open similar roles

This posting is closed, but here are live openings closest to it -- ranked by similarity, not by how well you'd qualify for them.

40%similar
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Same function Same country
40%similar
Lilly Indianapolis, Indiana, United States of America Associate
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40%similar
Merck West Point, Pennsylvania, United States of America Principal
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40%similar
Merck West Point, Pennsylvania, United States Intern/Fellow/Postdoc
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40%similar
AbbVie North Chicago, IL Associate Director
Same function Same country

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How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

40%
Director, Global Regulatory Affairs – Chemistry, Manufacturing and Controls (CMC), Platform Innovation – Synthetic Peptides and Oligonucleotides
Lilly · Indianapolis, Indiana, United States of America · Director
Function Therapeutic area Seniority Country
40%
Associate Principal Scientist/Engineer, Medical Device and Combination Products, Analytical
Merck · West Point, Pennsylvania, United States of America · Principal
Function Therapeutic area Seniority Country
40%
Senior Scientist II - Biologics Drug Product Development
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Function Therapeutic area Seniority Country
40%
Senior Scientist I - Peptide Analytical Chemistry
AbbVie · North Chicago, IL · Senior
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.