Horizon Therapeutics USA, Inc. Posted October 1, 2026

Observational Research Manager - Inflammation / Rare Disease

Remote, United States Full time
Clinical Development Rare Disease Manager
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Horizon Therapeutics USA, Inc. is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Career Category

Clinical

Job Description

HOW MIGHT YOU DEFY IMAGINATION?

You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission, to serve patients, drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

Observational Research Manager - Inflammation / Rare Disease

Live

What you will do

Let’s do this. Let’s change the world. In this vital role you will have responsibilities for research activities in the Inflammation / Rare Disease therapeutic/product facing team. An Observational Research Manager is recognized as a strong scientific contributor and is a first or contributing author for papers in peer-reviewed journals, abstracts for scientific congresses or for internal reports that enhance the company’s mission.

Responsibilities:

Implements/manages descriptive epidemiologic studies to characterize the incidence/prevalence of disease in US, EU, Asia, and emerging market countries

Implements/manages research projects involving the analysis of multiple types of data including medical claims, electronic health records, and prospective observational cohort studies

Provides safety research support across the life cycle of Amgen products, supports the development of risk management plans, and drives pharmacovigilance studies

Conducts literature reviews and prepares research reports and scientific manuscripts

Stays abreast of the latest developments in the field of observational research and drug development

Promotes awareness, understanding, and use of observational research methods

Communicates significant scientific information to a variety of audiences

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Observational Research Manager professional we seek is a research leader with these qualifications.

Basic Qualifications:

Doctorate degree

OR

Master’s degree and 3 years of scientific experience

OR

Bachelor’s degree and 5 years of scientific experience

OR

Associate’s degree and 10 years of scientific experience

OR

High school diploma / GED and 12 years of scientific experience

Preferred Qualifications:

Doctorate in Epidemiology or other subject with high observational research content

Experience in the design, execution, and analysis of observational research studies within Pharmaceutical or Public Health setting

Experience in research to support drug development

Experience working with secondary data systems, including administrative claims, EMR, registries

Experience in observational research project planning and management

Excellent verbal and writing communication and interpersonal skills

Experience working in multi-disciplinary teams

Experience in rare disease research and/or other inflammation therapeutic areas.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

Stock-based long-term incentives

Award-winning time-off plans and bi-annual company-wide shutdowns

Flexible work models, including remote work arrangements, where possible

 

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

 

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

. Salary Range

109,087.30USD -147,588.70 USD

Job details

Seniority
Manager
Function
Clinical Development
Therapeutic area
Rare Disease
Location
Remote, United States
Employment type
Full time

How this role compares

Computed from every other active Clinical Development role in our database, not just this employer's listings.

We currently track 288 comparable Manager Clinical Development roles across 68 biopharma companies.

288Comparable roles tracked
275Currently active
68Companies hiring similar roles
24Countries represented

Salary context

81 of 288 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Highest disclosed · Statistical Advisor · Gilead Sciences, Inc. $226,185/yr – $292,710/yr
Peer group range $95,500 – $259,448 (median $194,600)

Where these roles are based

Top locations among the 288 comparable roles

United States129
India49
Poland17
United Kingdom16
Japan10
China8

+ 18 more countries

Seniority mix

288 of 288 peers have a known seniority level

Manager162
Associate Director102
Associate24

Therapeutic area mix

22 of 288 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology14
Immunology5
Neuroscience1
Dermatology & Aesthetics1
Ophthalmology1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
AbbVie Manager
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Open in 4 locations

North Chicago, United StatesFlorham Park, United StatesIrvine, United StatesSouth San Francisco, United States
60%similar
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Same function Same seniority Same country
60%similar
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E.R. Squibb & Sons,L.L.C. Cambridge Crossing, United States Manager
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60%similar
Sanofi Vaccines US Inc. Swiftwater, United States Manager
Same function Same seniority Same country
60%similar
Sanofi Vaccines US Inc. Swiftwater, United States Manager
Same function Same seniority Same country

Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Manager, Clinical Data and Reporting Standards - SDTM Programming (Hybrid)
AbbVie · North Chicago, IL · Manager
Function Therapeutic area Seniority Country
60%
Manager, Clinical Data and Reporting Standards - SDTM Programming (Hybrid)
AbbVie · South San Francisco, CA · Manager
Function Therapeutic area Seniority Country
60%
Senior Manager, Data Scientist
E.R. Squibb & Sons,L.L.C. · Cambridge Crossing, United States · Manager
Function Therapeutic area Seniority Country
60%
Biostatistical Programming Manager
Amgen Inc. · Remote, United States · Manager
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.