Merck KGaA Posted September 5, 2026

NBE DMPK Lead (all genders), limited for 2 years

Darmstadt, Hessen, Germany FULL_TIME
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Merck KGaA is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Work Your Magic with us!

Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

Your Role:

At the intersection of scientific innovation and patient impact, this role places you at the heart of next-generation biotherapeutic development. As the NBE DMPK Lead, you will serve as the authoritative scientific expert for drug metabolism and pharmacokinetics across a portfolio of novel biological entities, including ADCs, AOCs, and multispecific biologics. You will define the DMPK strategy for each molecule, integrating PK, immunogenicity, and bioanalytical approaches to de-risk clinical development and drive health authority submissions. Applying Modeling and Simulation, you will generate data-driven insights to inform molecular design and translate preclinical findings into human dose predictions. Embedded in cross-functional project teams, you will guide peers and senior stakeholders, shaping the scientific direction of your projects.

This position is limited for two years.

Who You Are:

You hold a degree or equivalent qualification in Pharmacokinetics, Pharmaceutical or Biotechnological Sciences, Biomedical or Chemical Engineering, Applied Mathematics, or a related biological or chemical discipline; a doctoral degree with relevant industry experience is typical for this level.

You bring substantial professional experience in the pharmaceutical or biotechnology industry, with deep expertise in PK/PD concepts across drug discovery and development, including translational sciences and regulatory requirements for biotherapeutics such as ADCs, AOCs, and multispecific biologics.

You have hands-on experience with quantitative modeling approaches, including M&S tools, population PK software, QSP platforms, or programming environments such as Python or R; experience with AI/ML applications in drug development is a strong advantage.

You possess a solid understanding of adjacent disciplines, including pharmacology, toxicology, nonclinical safety, drug design, and bioanalytics, and can integrate insights across these areas to guide biotherapeutic engineering and optimization.

You communicate complex scientific concepts clearly and confidently to diverse audiences, including cross-functional project teams and senior stakeholders, and are comfortable influencing decisions without direct authority.

You are fluent in written and spoken English; proficiency in German or Italian is an advantage.

You bring strong organizational skills, intercultural awareness, and the ability to manage multiple project commitments with a high degree of autonomy.

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!

Job details

Seniority
Not listed
Function
Drug Discovery & Preclinical Research
Therapeutic area
Not listed
Location
Darmstadt, Hessen, Germany
Employment type
FULL_TIME

How this role compares

Computed from every other active Drug Discovery & Preclinical Research role in our database, not just this employer's listings.

We currently track 1022 comparable Drug Discovery & Preclinical Research roles across 81 biopharma companies.

1022Comparable roles tracked
937Currently active
81Companies hiring similar roles
31Countries represented

Salary context

429 of 1022 peers report a salary range (USD, annualized)

Peers share this role's job function. This posting doesn't list a seniority level, so peers aren't narrowed by seniority either -- the range below may span more levels than usual.

This roleSubject Not listed on this posting
Highest disclosed · Vice President, Therapeutics Immunology · ModernaTX, Inc. $272,200/yr – $490,100/yr
Peer group range $0 – $381,150 (median $159,000)

Where these roles are based

Top locations among the 1022 comparable roles

United States693
Germany49
China44
Switzerland36
United Kingdom35
France26

+ 25 more countries

Seniority mix

739 of 1022 peers have a known seniority level

Senior235
Principal171
Intern/Fellow/Postdoc84
Associate78
Director62
Associate Director43
Senior Director26
Manager26
Executive/VP14

Therapeutic area mix

134 of 1022 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Immunology54
Oncology41
Neuroscience23
Cardiovascular / CVRM6
Vaccines & Infectious Disease3
Respiratory3
Dermatology & Aesthetics2
Gastroenterology1
Rare Disease1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

40%similar
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Same function Same country
40%similar
Roche Penzberg, Bavaria, Germany Intern/Fellow/Postdoc
Same function Same country
40%similar
Roche Penzberg, Bavaria, Germany
Same function Same country
40%similar
Roche Penzberg, Bavaria, Germany
Same function Same country
40%similar
Pfizer Manuf. Deutschland GmbH Freiburg, Germany
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40%similar
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Notify me about similar jobs

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How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

40%
Principal Scientist Visual Inspection Steward
Lilly · Alzey, Rhineland-Palatinate, Germany · Principal
Function Therapeutic area Seniority Country
40%
Ausbildung 2027: Biologielaborant:in, Standort Penzberg
Roche · Penzberg, Bavaria, Germany · Seniority not listed
Function Therapeutic area Seniority Country
40%
Chemielaborant (m/w/d) befristet für 2 Jahre
Sandoz · Rudolstadt (Aeropharm GmbH), Germany · Seniority not listed
Function Therapeutic area Seniority Country
40%
Praktikum im Bereich naturwissenschaftliche Ausbildung für Studierende der Chemie (Ingelheim, Deutschland, Rheinland-Pfalz)
Boehringer Ingelheim · Ingelheim, Germany · Intern/Fellow/Postdoc
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.