Merck KGaA Posted September 11, 2026

MES Engineer

Jaffrey, New Hampshire, United States FULL_TIME
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Merck KGaA is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Work Location:  Jaffrey, New Hampshire

Shift:

Department:  LS-SC-UJBG Engineering Project

Recruiter:  Carolyn Angle Jones

This information is for internals only. Please do not share outside of the organization.

Your Role

The MES Engineer supports the effective use and continuous improvement of Siemens Opcenter MES at the Jaffrey site. This role provides day-to-day user and operational support, troubleshooting, business-facing configuration updates, and coordination with IT and cross-functional teams to help ensure MES supports site operations, quality, and compliance requirements. The role works closely with site SMEs, Operations, Quality, Validation, Automation, IT, and global digital teams, and may also support future MES expansion activities.

Key Responsibilities:

Perform MES modeling and configuration changes and enhancements to address operational needs, improve user experience, and align system use with site processes and user requirements.

Resolve workflow, reporting, integration, and usage issues in MES, in collaboration Opcenter SME and cross-functional teams.

Work with IT  to support resolution to issues affecting Production uptime as needed.

Support equipment and enterprise system interfaces by monitoring data flow, troubleshooting issues, and coordinating enhancements with cross-functional teams.

Lead change management activities for all MES maintenance and improvement initiatives for existing deployments, with support from the cross-functional team.

Perform change assessments and support qualification and validation activities for system updates, fixes, and enhancements

Create and maintain technical documentation aligned with GAMP, SDLC, and site procedures

Ensure MES-related activities comply with GxP, data integrity, EHS, and quality requirements

Partner with Operations, Quality, Validation, Automation, IT, and other teams to support continuous improvement and effective site use of MES

Who You Are

Minimum Qualifications:

Bachelor’s degree in STEM, engineering, computer science, technical management, or a related field

5+ years of manufacturing experience

2+ years of experience supporting manufacturing, OT, MES, or related digital systems in a production environment

Basic knowledge of manufacturing process support and system troubleshooting

Knowledge of or willingness to learn Siemens Opcenter MES configuration, including modeling objects, business rules, expressions, user queries, and integrations

Preferred Qualifications :

Working Knowledge of ISO & FDA regulations (such as ISO 9001, ISO 13485 or 21 CFR 820, 210 & 211).

Knowledge of SQL queries, SAP Business Objects, or related reporting and data tools

Familiarity with equipment integration and interface support, including OPC UA or similar connectivity

Understanding of GxP-regulated environments and GAMP requirements

Experience supporting system improvements, upgrades, or small enhancement activities

Strong analytical, problem-solving, and communication skills

Pay Range for this position: $116,400 - $174,600

The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here .

The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law.  This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.

Job details

Seniority
Not listed
Function
Manufacturing & CMC
Therapeutic area
Not listed
Location
Jaffrey, New Hampshire, United States
Employment type
FULL_TIME

How this role compares

Computed from every other active Manufacturing & CMC role in our database, not just this employer's listings.

We currently track 2556 comparable Manufacturing & CMC roles across 173 biopharma companies.

2556Comparable roles tracked
2343Currently active
173Companies hiring similar roles
56Countries represented

Salary context

662 of 2556 peers report a salary range (USD, annualized)

Peers share this role's job function. This posting doesn't list a seniority level, so peers aren't narrowed by seniority either -- the range below may span more levels than usual.

This roleSubject $116,400/yr – $174,600/yr
Lowest disclosed · Associate Director, Digital Scientific Workflows · Merck $0/hr – $0/hr (≈ $0–$0/yr)
Highest disclosed · VP, CMC Development Technical Strategy · ModernaTX, Inc. $272,200/yr – $490,100/yr
Peer group range $0 – $381,150 (median $122,400)

Where these roles are based

Top locations among the 2556 comparable roles

United States1232
India167
Germany134
France95
Ireland91
Netherlands77

+ 50 more countries

Seniority mix

1172 of 2556 peers have a known seniority level

Senior323
Manager265
Associate154
Intern/Fellow/Postdoc147
Principal88
Director79
Associate Director75
Senior Director34
Executive/VP7

Therapeutic area mix

12 of 2556 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Vaccines & Infectious Disease7
Rare Disease2
Oncology2
Dermatology & Aesthetics1

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The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

40%similar
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40%similar
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Lilly Indianapolis, Indiana, United States of America Director
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Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

40%
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Function Therapeutic area Seniority Country
40%
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Function Therapeutic area Seniority Country
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Function Therapeutic area Seniority Country
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Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.