Pfizer Posted November 10, 2026

Manufacturing Purification Manager

Andover, United States Full time
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Pfizer is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Use Your Power for Purpose

Our breakthroughs would not reach patients without our dedicated pharmaceutical manufacturing team. We rely on agile members who understand their crucial role in Pfizer's mission. Patients need colleagues like you who take pride in their work and strive to improve outcomes. Your efforts ensure that patients and physicians have timely access to necessary medicines. Your role will involve overseeing a Drug Substance Purification team and processes. This will involve determining manufacturing methods, procedures, and tooling requirements, as well as designing tools and planning production sequences in line with continuous improvement, Six Sigma, Lean, and other Good Manufacturing Principles (GMP). Your contributions will support Pfizer's mission to prioritize innovation, creativity, and respect for patients, colleagues, and society.

What You Will Achieve

In this role, you will:

Lead and manage people, technology, and financial resources within the department, ensuring alignment with short-term goals.

Actively share knowledge and collaborate within and across departments to foster innovation and continuous improvement.

Identify and implement potential improvements in processes or products, taking calculated risks to develop innovative ideas.

Solve moderately complex problems within your area of expertise and assist with cross-functional issues, providing technical guidance and oversight.

Oversee operational activities, manage multiple projects, and ensure compliance with regulations and GMP through effective execution of unit operations.

Manage the performance of direct reports through goal setting, coaching, mentoring, and ongoing assessment, recognizing and addressing development needs.

Solicit input, explain complex concepts, and persuade others to adopt a point of view, building alignment across manufacturing assets.

Own human performance event investigations as Lead Investigator, making autonomous decisions with minor impact and escalating significant decisions.

Form, lead, and facilitate cross-functional teams to execute key processes, ensuring accountability for the production activities of numerous Pfizer products.

Assist with short-range and long-range planning, including scheduling operations and staff, and coordinating facilities shutdowns and preventive maintenance.

Encourage the participation and perspectives of all team members. Effectively listen to and explains difficult issues to reach shared understanding and building alignment. Build alignment across manufacturing assets.

Provide technical guidance and act as a departmental liaison with primary support groups. Articulate challenges and solutions to technical and non-technical peers and to department management.

Motivate direct and indirect reports to ensure the function works cross-functionally.

Here Is What You Need (Minimum Requirements)

Applicant must have a bachelor's degree with at least 4 years of experience; OR a master's degree with at least 2 years of experience; OR a PhD with 0+ years of experience; OR as associate's degree with 8 years of experience; OR a high school diploma (or equivalent) and 10 years of relevant experience

A robust grasp of industry knowledge and business operations, such as financial basics, enterprise systems like payroll and inventory management

Proficiency in administrative, managerial, and technical report writing skills

Effective written and oral communication skills

Strong computer and presentation capabilities

Experience in people management

Knowledge of GMP and regulatory requirements

Bonus Points If You Have (Preferred Requirements)

Certifications in Continuous Improvement or Project Management

Familiarity with Local Environmental Health and Safety standards

Excellent interpersonal and communication skills

Experience in motivating and developing team members

Strong leadership and decision-making skills

Experience using common AI tools, including generative technologies such as ChatGPT or Microsoft Copilot, to support problem solving and enhance productivity. Demonstrated curiosity for exploring how these tools can improve outcomes and understanding of responsible AI practices, including risk management and ethical use

PHYSICAL/MENTAL REQUIREMENTS

Must be able to stand ~1-2 hours at a time.

Inspiring – Motivate and develop self and others to drive the business forward

Courage – Consistently demonstrate accountability and integrity

Resilience – Respond to change with agility, optimism and innovation

Decisive – Manage complexity to make timely informed decisions

Focus – Develop impactful short- and long-term solutions for our customers and patients

Connected – collaborate with others to accomplish shared goa

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

first shift, rotating

Occasional off-shift requirements

OTHER JOB DETAILS

Last Date to Apply for Job: Nov 17, 2026.

Referral Bonus Eligibility: YES

Eligible for Relocation Package: YES

Work Location Assignment: On Premise

The annual base salary for this position ranges from $106,000.00 to $176,600.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 15.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations.  These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure.  Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.  Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.  If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.  Pfizer is an E-Verify employer.  This position requires permanent work authorization in the United States.

Pfizer endeavors to make   www.pfizer.com/careers   accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email   disabilityrecruitment@pfizer.com . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.

To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on  Pfizer Careers .

Manufacturing

Job details

Seniority
Manager
Function
Manufacturing & CMC
Therapeutic area
Not listed
Location
Andover, United States
Employment type
Full time

How this role compares

Computed from every other active Manufacturing & CMC role in our database, not just this employer's listings.

We currently track 596 comparable Manager Manufacturing & CMC roles across 98 biopharma companies.

596Comparable roles tracked
547Currently active
98Companies hiring similar roles
40Countries represented

Salary context

178 of 596 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $106,000/yr – $176,600/yr
Lowest disclosed · Warehouse Associate I (M-F 11am-7:30pm) · AbbVie $16/hr – $29/hr (≈ $33,280–$60,320/yr)
Highest disclosed · Associate Director / Director - Biologics Drug Product Development · AbbVie $160,500/yr – $305,000/yr
Peer group range $46,800 – $232,750 (median $165,225)

Where these roles are based

Top locations among the 596 comparable roles

United States333
India50
Ireland24
Japan23
Netherlands19
China17

+ 34 more countries

Seniority mix

596 of 596 peers have a known seniority level

Manager350
Associate142
Associate Director104

Therapeutic area mix

6 of 596 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Rare Disease3
Vaccines & Infectious Disease2
Immunology1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
Gilead Sciences, Inc. Foster City, United States Manager
Same function Same seniority Same country
60%similar
RayzeBio, Inc Indianapolis, United States Manager
Same function Same seniority Same country
60%similar
Celgene - Summit (Corp) Summit West, United States Manager
Same function Same seniority Same country
60%similar
Celgene - Summit (Corp) Summit West, United States Manager
Same function Same seniority Same country
60%similar
E.R. Squibb & Sons,L.L.C. Princeton Pike, United States Manager
Same function Same seniority Same country
60%similar
Amgen Inc. Holly Springs, United States Manager
Same function Same seniority Same country

Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

Or follow a whole field: get every new Manufacturing & CMC job in the United States, and choose locations and companies.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Senior Manager, Site SAP Business Lead
Gilead Sciences, Inc. · Foster City, United States · Manager
Function Therapeutic area Seniority Country
60%
Manager, Computer System Validation (CSV) – Cell Therapy
Celgene - Summit (Corp) · Summit West, United States · Manager
Function Therapeutic area Seniority Country
60%
Front Line Manufacturing Manager (Bulk Drug Substance - Downstream) - Night Shift
Amgen Inc. · Holly Springs, United States · Manager
Function Therapeutic area Seniority Country
60%
Senior Manager Instrumentation and Maintenance
Amgen Inc. · Holly Springs, United States · Manager
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.