IT Business Analyst – PAS|X MES Upgrade (Pharmaceutical Manufacturing) – Contract,
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12-month contract
Start date: January 2027
North Ryde (Macquarie Park), Sydney NSW
Free onsite parking and public transport
Join AstraZeneca as a contract IT Business Analyst and lead local delivery of our PAS|X (MES) upgrade at our North Ryde pharmaceutical manufacturing plant in Sydney. Help keep life-changing medicines flowing to patients.
About AstraZeneca
AstraZeneca is a global, science-led biopharmaceutical company that discovers, develops and commercialises prescription medicines in Oncology; Cardiovascular, Renal and Metabolism; Respiratory & Immunology; and Rare Disease. In Australia, we have delivered life-changing medicines to patients for more than 60 years.
About AstraZeneca Operations
Our Global Operations teams combine human ingenuity with AI to transform how medicines are made and supplied. Our network spans 25 production facilities across 15 countries, with around 16,000 colleagues manufacturing billions of medicines each year, from tablets and inhalers to advanced biologics and injectables.
Our North Ryde manufacturing plant is a world-class site with a proven record of outstanding supply performance, and one of the most successful in our global network. Our culture is fast-paced, collaborative and focused on patients.
Key responsibilities:
As IT Business Analyst, you will lead local delivery of the PAS|X upgrade from requirements through to go-live and hypercare, keeping production running and the system validated.
Lead local upgrade delivery: scope, plan, RAID logs and status reporting.
Capture requirements and assess impact on configuration, interfaces and master batch records (eBRs).
Produce GxP validation documentation in line with 21 CFR Part 11 and Annex 11.
Coordinate testing (IQ/OQ/PQ support, UAT), cutover and go-live readiness.
Support PAS|X integration with SAP and shop-floor equipment.
Work with the vendor and global program office, provide hypercare and hand over to business-as-usual support.
Essential skills and experience
Degree in information systems, computer science or a related field (or equivalent experience).
3+ years as an IT Business Analyst in pharma, biotech or regulated manufacturing.
Hands-on experience with SAP and Koerber (Werum) PAS|X, including a PAS|X upgrade or major release.
Strong GxP knowledge: 21 CFR Part 11, Annex 11, GAMP 5 and risk-based validation.
Agile or hybrid project delivery, including test planning, release and change control.
Strong communication and stakeholder skills, and able to work independently from day one.
Desirable skills
Multi-site or multi-environment upgrade experience.
Familiarity with LIMS, data historians and ISA-95/ISA-88.
Exposure to SAP integration patterns (BAPIs/IDocs, web services) and interface testing.
So, what’s next?
Ready to bring fresh thinking to the table?
Candidates must have valid Australian work rights. We will also consider candidates on a Working Holiday visa (subclass 417 or 462), subject to their visa work conditions.
Guidance on AI use
We support you using AI tools responsibly in the recruitment process to help you be at your best and showcase your knowledge, skills and abilities. Review our guide at careers.astrazeneca.com/aiguidance.
Where can I find out more?
Visit our Global Website: www.astrazeneca.com
Follow AstraZeneca on LinkedIn: https://www.linkedin.com/company/1603/
Explore our Operations careers page and the AstraZeneca Australia and New Zealand careers page
AstraZeneca in Australia has been formally recognised as a Silver Tier Employer within the Australian Workplace Equality Index (AWEI). Visit our ANZ Careers Page to learn more about our commitment to fostering a flexible, diverse and inclusive environment. We recognise that any recruitment process may present challenges. If there is anything we can do to make our recruitment process more accessible for you, please let us know via our accessibility form.
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
Date Posted
04-Nov-2026
Closing Date
06-Dec-2026
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
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