Ipsen Biopharmaceuticals Inc. Posted October 23, 2026

Head of Commercial Operations & Strategic Initiatives, Rare Disease

Cambridge (US), United States Full time
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Ipsen Biopharmaceuticals Inc. is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

Title:

Head of Commercial Operations & Strategic Initiatives, Rare Disease

Company:

Ipsen Biopharmaceuticals Inc.

About Ipsen:

Ipsen is a mid-sized global biopharmaceutical company with a focus on transformative medicines in three therapeutic areas: Oncology, Rare Disease and Neuroscience. Supported by nearly 100 years of development experience, with global hubs in the U.S., France and the U.K, we tackle areas of high unmet medical need through research and innovation.

Our passionate teams in more than 40 countries are focused on what matters and endeavor every day to bring medicines to patients in 88 countries. We build a workplace that champions human-centric leadership and fosters a culture of collaboration, excellence and impact. At Ipsen, every individual is empowered to be their true selves, grow and thrive alongside the company’s success. Join us on our journey towards sustainable growth, creating real impact on patients and society!

For more information, visit us at https://www.ipsen.com/   and follow our latest news on LinkedIn and Instagram .

Job Description:

The Head of Commercial Operations & Strategic Initiatives is a member of the Rare Disease Business Unit (RDBU) Leadership Team and serves as the strategic and operational deputy to the SVP, U.S. Rare Disease. The role is accountable for translating franchise strategy into an integrated operating plan, establishing the management systems required to deliver business objectives, and leading the RDBU portfolio of enterprise priorities and transformation initiatives.

This leader owns RDBU governance, strategic and business planning, performance management, commercial operations, organizational effectiveness, and cross-functional execution. Working across Sales, TLLs, Marketing, Market Access, Medical, Finance, Business Operations & Strategy (BOS), and other enterprise partners, the role identifies trade-offs, escalates risks, enables timely executive decisions and holds initiative owners accountable for delivery.

The role leads a team and influences senior and key stakeholders across the organization to advance near-and long-term portfolio performance.

WHAT - Main Responsibilities

Strategic Leadership & Governance

Serve as strategic advisor and Chief of Staff to the SVP, shaping the RDBU agenda, framing critical business decisions, anticipating enterprise risks and opportunities, and driving Leadership Team effectiveness and accountability.

Design and lead the RDBU governance and management operating system, including Leadership Team forums, operating reviews, executive and board communications, decision processes, and accountability mechanisms.

Partner with RDBU LT to define objectives, shape the culture, and drive alignment with cross-functional teams.

Own the integrated RDBU planning process, aligning strategic, brand, operational, workforce, and financial plans; identifying interdependencies and trade-offs; and ensuring resources are directed to the highest-value priorities.

Serve as the RDBU champion and expert for key account management, including building operating mechanisms and organizational capabilities that accelerate adoption of RDBU products in priority health systems.

Identify organizational capabilities and operating model enhancements that accelerate portfolio growth and long-term success.

Commercial Excellence, Operations & Analytics

Build, lead, and develop a high-performing Commercial Operations and Strategic Initiatives team (2-3 people), establishing clear accountabilities, strengthening capabilities, and creating succession and development plans.

Drive strategic and operational excellence by identifying, exploring, and implementing innovative commercial capabilities.

Oversee performance monitoring, recognition programs, and continuous improvement efforts.

Own the RDBU performance-management framework in partnership with BOS, including RDBU KPIs, leading and lagging indicators, dashboards, business insights, and executive reporting that enable timely decisions and corrective action.

Provide strategic leadership and RDBU business ownership for sales operations capabilities, including targeting, segmentation, territory design, incentive effectiveness, CRM adoption, field-force analytics, and performance reporting, in partnership with BOS and field leadership.

Lead enterprise-wide launch readiness and commercialization planning for the Rare Disease Business Unit, establishing governance, integrated workplans, decision milestones, risk mitigation, and executive-level progress reporting.

Set the operational excellence agenda for the RDBU, leading enterprise-wide process redesign, operating-model improvements, and capability investments that remove barriers, increase organizational agility, and improve business performance.

Translate market, customer, and performance insights into strategic recommendations that improve business outcomes.

Cross-Functional Execution & Strategic Initiatives

Build and lead Health System Account team responsible for RDBU priority account strategic planning and execution to enhance patient diagnosis and treatment pathways, referral and care coordination and access to the RDBU treatments

Lead operating-model and capability transformation across the RDBU, identifying and implementing the organizational, process, technology, and insight capabilities required to support portfolio growth

Build alignment among senior cross-functional leaders, resolve competing priorities, and create the conditions for timely enterprise decisions and coordinated execution'

HOW - Knowledge & Experience

Knowledge & Experience (essential):

At least 12 years of related experience with a Bachelor’s degree; or 8 years and a Master’s degree; or equivalent experience

Demonstrated success serving as a senior advisor to business-unit or enterprise leadership and leading through influence across complex matrixed organizations

Proven accountability for integrated business planning, governance, performance management, and execution of enterprise-level strategic priorities

Experience building and leading high-performing teams, including direct people-management responsibility and leadership of cross-functional teams

Demonstrated ability to synthesize complex market, customer, financial, and operational information into clear executive recommendations and decisions

Experience leading organizational transformation, operating-model change, or capability-building initiatives with measurable business impact

Strong commercial and financial acumen, including resource prioritization, investment evaluation, KPI development, and performance management

Strong communication and interpersonal skills along with the ability to influence others

Working within an environment of strict compliance to all appropriate regulatory guidelines to successfully design and execute tactics, programs and tools that achieve business objectives

Passion for patients and a deep commitment to support success of high performing teams with high integrity and in compliance with all policies and regulations

Able to work on a hybrid model including in-office multiple times per week from our Cambridge, MA HQ

Willingness/ability to travel domestically; International travel may be required

Education / Certifications (essential):

BA/BS is required

Education / Certifications (preferred):

MBA is strongly preferred

Compensation

The annual base salary range for this position is $217,500 - $300,000

The pay range displayed above is the range of base pay compensation within which Ipsen expects to pay for this role at the time of this posting. Individual compensation within this range depends on a variety of factors, including, but not limited to, prior education and experience, job-related knowledge and demonstrated skills.

This job is eligible to participate in our incentive compensation program as well as our long-term incentives program.

At Ipsen we are proud to offer a comprehensive employee benefits package, including 401(k) with company contributions, group medical, dental and vision coverage, life and disability insurance, short- and long-term disability insurance, as well as flexible spending accounts. Ipsen also provides parental leave, paid time off, a discretionary winter shutdown, well-being allowance, commuter benefits, and much more.

We are committed to creating a workplace where everyone feels heard, valued, and supported; where we embrace “The Real Us”. The value we place on different perspectives and experiences drives our commitment to inclusion and equal opportunities. When we include diverse ways of thinking, we make more thoughtful decisions and discover more innovative solutions. Together we strive to better understand the communities we serve. This means we also want to help you perform at your best when applying for a role with us. If you require any adjustments or support during the application process, please let the recruitment team know. This information will be handled with care and will not affect the outcome of your application. Ipsen is an equal opportunity employer that strictly prohibits unlawful discrimination. We recruit, employ, train, compensate, and promote without regard to an individual’s race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.

Job details

Seniority
Not listed
Function
BD&L & Strategic Planning
Therapeutic area
Rare Disease
Location
Cambridge (US), United States
Employment type
Full time

How this role compares

Computed from every other active BD&L & Strategic Planning role in our database, not just this employer's listings.

We currently track 396 comparable BD&L & Strategic Planning roles across 78 biopharma companies.

396Comparable roles tracked
361Currently active
78Companies hiring similar roles
41Countries represented

Salary context

126 of 396 peers report a salary range (USD, annualized)

Peers share this role's job function. This posting doesn't list a seniority level, so peers aren't narrowed by seniority either -- the range below may span more levels than usual.

This roleSubject $217,500/yr – $300,000/yr
Lowest disclosed · Manager, Portfolio Management · Sandoz $0/hr – $0/hr (≈ $0–$0/yr)
Peer group range $0 – $380,750 (median $209,000)

Where these roles are based

Top locations among the 396 comparable roles

United States187
China56
United Kingdom17
India16
Germany15
Switzerland12

+ 35 more countries

Seniority mix

286 of 396 peers have a known seniority level

Director92
Manager71
Associate Director42
Senior Director30
Intern/Fellow/Postdoc16
Senior15
Principal8
Executive/VP7
Associate5

Therapeutic area mix

65 of 396 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology20
Neuroscience12
Immunology12
Dermatology & Aesthetics11
Vaccines & Infectious Disease3
Cardiovascular / CVRM2
Respiratory2
Gastroenterology2
Ophthalmology1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

40%similar
Lilly Indianapolis, Indiana, United States of America Senior Director
Same function Same country
40%similar
AbbVie North Chicago, IL
Same function Same country
40%similar
AbbVie Irvine, CA Associate Director
Same function Same country
40%similar
Novartis Cambridge (USA), United States Principal
Same function Same country
40%similar
Gilead Sciences, Inc. Foster City, United States Executive/VP
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40%similar
Regeneron Pharmaceuticals, Inc (USA) Tarrytown, United States Manager
Same function Same country

Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

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How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

40%
Sr. Director - Strategic Alliances (SMDD)
Lilly · Indianapolis, Indiana, United States of America · Senior Director
Function Therapeutic area Seniority Country
40%
Principal Scientist II, Translational Biomarker Strategy Lead
Novartis · Cambridge (USA), United States · Principal
Function Therapeutic area Seniority Country
40%
Business Development Senior Manager
Amgen Inc. · Thousand Oaks, United States · Manager
Function Therapeutic area Seniority Country
40%
Director, Business Development/KAM, Fremont CA/Bay Area (Fremont, CA, United States, California)
Boehringer Ingelheim · Fremont, California, United States · Director
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.