GlaxoSmithKline LLC Posted September 10, 2026

GPS Continuous Improvement Manager

King of Prussia, United States Full time
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GlaxoSmithKline LLC is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

We manufacture and supply reliable, high-quality medicines and vaccines to meet patients’ needs and drive our performance.

Our network of 37 medicines and vaccines manufacturing sites delivered 1.7 billion packs of medicines and 409 million vaccine doses in 2024 to help make a positive impact on the health of millions of people. Our supply chain is not just core to our operations; it’s vital to bringing our innovations to patients as quickly, efficiently and effectively as possible. Technology is transforming how we manufacture medicines and vaccines, enabling us to increase the speed, quality and scale of product supply.

We need the very best minds and capability to help us on our journey to make more complex products, harnessing the power of smart manufacturing technologies including robotics, digital solutions and artificial intelligence to deliver for patients.

As a GPS Continuous Improvement Manager, you will lead continuous improvement activities across the site to improve performance around safety, quality, delivery, cost and people pillars. You will work closely with manufacturing, quality, MSAT, engineering, EHS and supply chain teams to identify opportunities, run improvement projects, and embed sustainable ways of working. We value practical problem-solving, coaching, and collaboration. This role offers strong growth, visible impact on operations, and alignment with our mission of uniting science, technology and talent to get ahead of disease together.

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

Lead end-to-end continuous improvement projects using Lean and Six Sigma to improve safety, quality, delivery and cost.

Coach and develop site teams and leaders to adopt GSK Production System (GPS) standards including standard work, tiered performance management, and structured problem solving.

Establish and manage performance routines and metrics to track progress and report business impact.

Use data and digital tools to turn insights into clear, timely actions at the frontline.

Standardize and sustain improvements through processes, training, and documented controls.

Partner with stakeholders across functions to remove barriers and ensure changes are implemented and measured.

Working pattern

This role is on-site. You will be expected to work on-site regularly to engage with frontline teams and attend meetings. Some remote work is supported to enable flexible collaboration in case by case basis.

Why You?

Basic Qualification

We are seeking professionals with the following required skills and qualifications to help us achieve our goals

Bachelor’s degree in engineering, operations, supply chain, or related field such as math, science, technology, Stem etc.

Lean/Six Sigma Green Belt certification

8+ years of experience leading continuous improvement, operational excellence or production-system deployment in an operating environment.

4+ years of experience in regulated manufacturing, such as biopharmaceutical, pharmaceutical, medical device or a comparable environment. GxP or FDA experience is preferred.

2+ years of experience leading teaching and coaching effortd for continuous improvement including problem solving using DMAIC or A3 methodologies

1+ years of experience with Leading strategy deployment (Hoshin Kanri) at site or business-unit level

1+ year of experience building or strengthening a Lean management system

1 + years of experience leading cross-functional change

Preferred Qualification

If you have the following characteristics, it would be a plus

Line leadership experience in manufacturing or supply chain with direct accountability for operational performance.

Lean/Six Sigma Black Belt or Master Black Belt certification.

Experience designing and delivering capability building programs

Experience establishing or improving an employee improvement-idea process, with evidence of participation, implementation and sustained use.

Experience using data and analytics in improvement work and assessing where digital, automation or AI can add value.

Proven track record delivering measurable operational improvements.

Strong facilitation and coaching skills with the ability to influence across functions.

Practical knowledge of ERP or MES systems and industrial analytics.

Project management experience, including sprint planning and dependency management.

Experience developing leaders and building capability at scale.

Familiarity with statistical tools or process capability analysis.

#LI-GSK

Skills

Analytical Thinking, Artificial Intelligence (AI), Biopharmaceutical Manufacturing, Data-Driven Decision Making, Data Integrity, Digital Fluency, GxP Regulations, Influencing Without Authority, Lean Management, Problem Solving, Process Improvements, Project Management, Risk Awareness, Workshop Facilitation

Please visit  GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at -  usrecruitment.adjustments@gsk.com

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Job details

Seniority
Manager
Function
Manufacturing & CMC
Therapeutic area
Not listed
Location
King of Prussia, United States
Employment type
Full time

How this role compares

Computed from every other active Manufacturing & CMC role in our database, not just this employer's listings.

We currently track 452 comparable Manager Manufacturing & CMC roles across 73 biopharma companies.

452Comparable roles tracked
433Currently active
73Companies hiring similar roles
31Countries represented

Salary context

141 of 452 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject Not listed on this posting
Lowest disclosed · Associate Director, Digital Scientific Workflows · Merck $0/hr – $0/hr (≈ $0–$0/yr)
Highest disclosed · Regional Manager - Megasys · Merck KGaA $220,000/yr – $250,000/yr
Peer group range $0 – $235,000 (median $157,000)

Where these roles are based

Top locations among the 452 comparable roles

United States272
India55
Netherlands16
Ireland16
United Kingdom11
Japan10

+ 25 more countries

Seniority mix

452 of 452 peers have a known seniority level

Manager247
Associate131
Associate Director74

Therapeutic area mix

3 of 452 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Rare Disease2
Vaccines & Infectious Disease1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

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60%similar
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Regeneron Pharmaceuticals, Inc (USA) Armonk, United States Manager
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60%similar
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Same function Same seniority Same country

Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
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Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.