Novartis Posted August 23, 2026

Executive Director, Semantic and Knowledge Engineering

East Hanover, United States FULL_TIME
Data & Digital Executive/VP
Notify me about similar jobs

Novartis is the source of truth for this posting and owns the application process. We surface normalized context and market comparison you won't find on the original listing.

About this opportunity

#LI-HybridReporting to the VP, Applied AI, Data Science, and Commercial Intelligence, the Executive Director, Semantic and Knowledge Engineering leads the strategy, architecture, and implementation of the enterprise semantic layer and knowledge engineering capabilities that power NovaOS. This role is responsible for creating a trusted, reusable knowledge foundation that connects data, business concepts, ontologies, taxonomies, and AI agents to enable consistent reasoning, interoperability, and scalable enterprise intelligence. The ideal location for this role is East Hanover but remote work may be possible (there may be some restrictions based on legal entity). Please note that this role would not provide relocation as a result. If associate is remote, all home office expenses and any travel/lodging to specific East Hanover for periodic live meetings will be at the employee’s expense. The expectation of working hours and travel (domestic and/or international) will be defined by the hiring manager. This position will require 10% travel.

Key Responsibilities:Define and execute the enterprise strategy for semantic technologies, knowledge engineering, and knowledge graph capabilities. Lead the development and governance of enterprise ontologies, taxonomies, business vocabularies, and semantic models that establish a shared understanding across the organization. Design and implement the enterprise semantic layer that enables trusted AI, consistent analytics, interoperability, and reusable business knowledge. Partner with Applied AI, Data Science, Product Management, Engineering, and Business teams to embed semantic capabilities into NovaOS products and AI solutions. Establish governance, metadata management, knowledge lifecycle processes, and quality standards for enterprise knowledge assets. Drive innovation in knowledge graphs, retrieval-augmented generation (RAG), semantic search, reasoning engines, and AI-enabled knowledge management. Build and lead a high-performing team of semantic engineers, ontology specialists, and knowledge engineers while fostering technical excellence and innovation. Essential Requirements: Education: • Bachelor's or advanced degree in Computer Science, Information Science, Artificial Intelligence, Data Science, Bioinformatics, or a related discipline. 10+ years of experience in semantic technologies, knowledge engineering, enterprise architecture, data management, or AI platforms, including leadership experience. Deep expertise with ontologies, taxonomies, metadata, RDF/OWL, knowledge graphs, graph databases, semantic web technologies, and enterprise information architecture. Experience building enterprise semantic platforms that enable AI, analytics, search, and data interoperability at scale. Exceptional leadership, executive communication, and cross-functional stakeholder management skills. Desirable Requirements: Experience applying semantic technologies to generative AI, agentic AI, RAG, and enterprise AI platforms. Experience in pharmaceutical, healthcare, or other highly regulated industries. Novartis Compensation Summary: The salary for this position is expected to range between $225,400 and $418,600 per year.  The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.  Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.  US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.

Job details

Seniority
Executive/VP
Function
Data & Digital
Therapeutic area
Not listed
Location
East Hanover, United States
Employment type
FULL_TIME

How this role compares

Computed from every other active Data & Digital role in our database, not just this employer's listings.

We currently track 13 comparable Executive/VP Data & Digital roles across 6 biopharma companies.

13Comparable roles tracked
13Currently active
6Companies hiring similar roles
3Countries represented

Salary context

9 of 13 peers report a salary range (USD, annualized)

Peers share this role's job function and a matching or adjacent seniority level -- not necessarily the same therapeutic area or country.

This roleSubject $225,400/yr – $418,600/yr
Lowest disclosed · Executive Director, Head of Agentic Factory - Remote · Novartis $225,400/yr – $418,600/yr
Peer group range $322,000 – $339,950 (median $339,950)

Where these roles are based

Top locations among the 13 comparable roles

United States11
India1
United Kingdom1

Seniority mix

13 of 13 peers have a known seniority level

Executive/VP9
Senior Director4

Therapeutic area mix

3 of 13 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Immunology2
Ophthalmology1

Similar opportunities

The closest matches from our peer group, ranked by how similar they are, not how well you'd qualify for them -- treat this as market context, not a guaranteed shortlist; a weak match is labeled as one below.

60%similar
Regeneron Pharmaceuticals, Inc (USA) Tarrytown, United States Executive/VP
Same function Same seniority Same country
60%similar
Regeneron Healthcare Solutions, Inc (USA) Sleepy Hollow, United States Executive/VP
Same function Same seniority Same country
60%similar
Regeneron Healthcare Solutions, Inc (USA) Sleepy Hollow, United States Executive/VP
Same function Same seniority Same country
60%similar
Novartis Remote Position (USA), United States Executive/VP
Same function Same seniority Same country
60%similar
Novartis Distant Employee - Distant Working Arrangement (DWA) (USA), United States Executive/VP
Same function Same seniority Same country
60%similar
Novartis Remote Position (USA), United States Executive/VP
Same function Same seniority Same country

Notify me about similar jobs

Get an email when we spot other openings like this one – same job function, comparable seniority, roles you'd actually want to see.

How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

60%
Executive Director, Responsible AI & Enterprise Governance
Regeneron Pharmaceuticals, Inc (USA) · Tarrytown, United States · Executive/VP
Function Therapeutic area Seniority Country
60%
Executive Director, Head of Agentic Factory - Remote
Novartis · Remote Position (USA), United States · Executive/VP
Function Therapeutic area Seniority Country
60%
Executive Director - Data Management, Analytics, AI & Architecture
Regeneron Pharmaceuticals, Inc (USA) · Sleepy Hollow, United States · Executive/VP
Function Therapeutic area Seniority Country
50%
Senior Director, Biostatistics - Immunology & Inflammation
Regeneron Pharmaceuticals, Inc (USA) · Warren, United States · Senior Director
Function Therapeutic area Adjacent seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.