Novartis Posted September 18, 2026

Executive Clinical Program Leader - Translational Clinical Oncology

Cambridge (USA), United States FULL_TIME
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About this opportunity

Executive Clinical Program Leader - Translational Clinical OncologyLocation: Cambridge, MA, USAWork Arrangement: OnsiteThe Executive Clinical Program Leader (ECPL) provides strategic medical and scientific leadership for the development of multiple experimental agents within the Translational Clinical Oncology (TCO) portfolio. The role spans from early target identification through transition into later-stage development, partnering closely with development teams to accelerate decision-making and portfolio advancement. The ECPL also provides scientific and clinical expertise to evaluate external innovation opportunities and business development initiatives.

Key ResponsibilitiesProvide strategic medical and scientific leadership across early oncology development programs.Represent Translational Clinical Oncology programs at internal governance and leadership boards.Lead clinical strategy development and provide senior clinical input for clinical studies and preclinical research projects.Review and provide feedback on key study documents, including protocols, investigator brochures, and regulatory submissions.Contribute scientific and clinical expertise to business development, licensing evaluations, and portfolio reviews.Lead and oversee external collaborations and strategic partnerships.Mentor colleagues and serve as an expert resource across Biomedical Research and the broader organization.Ensure the safe, ethical, and compliant conduct of clinical trials in accordance with GCP and company procedures.Engage with external experts, investigators, and health authorities in support of early oncology clinical development.Contribute to scientific publications, abstracts, and presentations for internal and external audiences.Essential RequirementsMD required; MD/PhD preferred.Board certification (or equivalent expertise) in Hematology-Oncology.7+ years of experience leading complex global early-phase hematology-oncology clinical programs within the pharmaceutical or biotechnology industry.Strong experience in translational hematology/oncology and clinical research.Recognized scientific and clinical expertise demonstrated through publications and professional contributions.Broad knowledge of oncology drug development and clinical trial execution.Excellent written and verbal communication skills.Proven leadership and people management experience.Strong mentoring and talent development capabilities.High ethical standards and commitment to improving outcomes for patients with cancerRewards At Novartis, we’re committed to reimagining medicine together - and rewarding the people who make it happen.  The rewards of being part of our team go far beyond base pay and incentives. We also offer a variety of competitive benefits in kind to help you thrive personally and professionally, such as insurance plans, retirement plans, wellbeing resources and global recognition programs. In addition, we provide flexible and hybrid working options, where possible, and a minimum of 14 weeks paid parental leave.  Expected Annual Base Salary Range for role: USA: $288,400.00 - 535,600.00 USD Annual The salary offered is determined based on gender-neutral objectives, such as relevant skills, competencies and experience in accordance with the Novartis pay setting policy and upon joining Novartis will be reviewed periodically.   In addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters. Further details will be provided during the application process.   Pay equity is a fundamental principle of our employment policy and reflects our commitment to create a diverse, equitable and inclusive environment that treats all employees with dignity and respect, as outlined in our Code of Ethics.  Read our brochure to learn more about our global total rewards offering: https://www.novartis.com/sites/novartis_com/files/novartis-life-handbook.pdf  Note: Benefits and compensation may vary by country and are subject to local legal requirements, including provisions of collective bargaining agreements where applicable. A full overview of your compensation package, including any relevant collective bargaining agreement details applicable to your role based on your employment location and Novartis employer entity, will be communicated separately to you during the application process.     Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Job details

Seniority
Not listed
Function
Clinical Development
Therapeutic area
Oncology
Location
Cambridge (USA), United States
Employment type
FULL_TIME

How this role compares

Computed from every other active Clinical Development role in our database, not just this employer's listings.

We currently track 1416 comparable Clinical Development roles across 105 biopharma companies.

1416Comparable roles tracked
1301Currently active
105Companies hiring similar roles
52Countries represented

Salary context

418 of 1416 peers report a salary range (USD, annualized)

Peers share this role's job function. This posting doesn't list a seniority level, so peers aren't narrowed by seniority either -- the range below may span more levels than usual.

This roleSubject $288,400/yr – $535,600/yr
Lowest disclosed · Patient Safety, Medical Director · Vertex Pharmaceuticals Inc (US) $0/hr – $0/hr (≈ $0–$0/yr)
Peer group range $0 – $468,000 (median $198,000)

Where these roles are based

Top locations among the 1416 comparable roles

United States738
India124
United Kingdom88
China69
Japan35
Poland33

+ 46 more countries

Seniority mix

967 of 1416 peers have a known seniority level

Manager276
Director236
Senior149
Associate Director118
Senior Director63
Associate40
Principal34
Executive/VP30
Intern/Fellow/Postdoc21

Therapeutic area mix

205 of 1416 peers have a known therapeutic area; the rest are genuinely unlabeled, not hidden

Oncology103
Immunology36
Neuroscience32
Cardiovascular / CVRM11
Respiratory9
Vaccines & Infectious Disease4
Dermatology & Aesthetics4
Ophthalmology3
Rare Disease2
Gastroenterology1

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How we calculate "similar"

No black box, no LLM guesswork: a deterministic score built from four normalized attributes. Here's this role's own peer group at different match levels, so you can see the mechanism, not just the result.

Every comparison starts from the same 100-point budget: 25 for working in the same function, 40 for the same therapeutic area, 20 for the same or adjacent seniority, 15 for the same country. A dimension we can't confirm on both sides contributes nothing, never a guess, never a free pass.

80%
Global Development Medical Director, Hematology Oncology
AstraZeneca · Gaithersburg, Maryland, United States of America · Director
Function Therapeutic area Seniority Country
80%
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GlaxoSmithKline LLC · Upper Providence, United States · Seniority not listed
Function Therapeutic area Seniority Country
80%
Medical Director, Clinical Development, Oncology (Lung, Breast, Colorectal, Gastric Cancers)
Regeneron Pharmaceuticals, Inc (USA) · Tarrytown, United States · Director
Function Therapeutic area Seniority Country
80%
Clinical Director, Oncology Early Development
Merck · Rahway, New Jersey, United States of America · Director
Function Therapeutic area Seniority Country
Unmatched or unknown dimensions score exactly the same: 0 points, never a partial guess. A role we know almost nothing about beyond its function bottoms out at 25%; it never inflates to 100% just because there's little to compare against. Seniority uses a defined ladder (Associate → Manager → Associate Director → Senior → Principal → Director → Senior Director → Executive/VP) so "Director" and "Senior Director" count as adjacent, but "Director" and "Executive/VP" do not.